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Academic Journals
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From:International Journal of Retina and Vitreous (Vol. 8, Issue 1) Peer-ReviewedBackground The somatotrophic axis, including hypothalamic growth hormone (GH)-releasing hormone (GHRH), pituitary GH and circulating IGF-I, is critical for body size. However, the local production of GH/IGF-I (and...
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From:Expert Review of Endocrinology & Metabolism (Vol. 6, Issue 2) Peer-ReviewedAuthor(s): Marie-Lise Jaffrain-Rea 1 2 3 , Adrian F Daly 4 , Mariolina Angelini 1 , Patrick Petrossians 4 , Vincent Bours 4 , Albert Beckers [[dagger]â ] 5 Keywords: AIP; aryl hydrocarbon receptor-interacting...
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From:PLoS ONE (Vol. 6, Issue 8) Peer-ReviewedContributions of somatotropic hormonal activity to memory functions in humans, which are suggested by clinical observations, have not been systematically examined. With previous experiments precluding a direct effect of...
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From:PLoS ONE (Vol. 8, Issue 1) Peer-ReviewedPrevious studies have shown that the locus control region (LCR) and the promoter of the growth hormone (GH) gene can control the expression of GH. Therefore, lenti- and retro-viral vectors with these elements might be...
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From:PLoS ONE (Vol. 9, Issue 10) Peer-ReviewedButyrate is a short-chain fatty acid (SCFA) closely related to the ketone body [beta]-hydroxybutyrate (BHB), which is considered to be the major energy substrate during prolonged exercise or starvation. During fasting,...
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From:Science (Vol. 244, Issue 4908) Peer-ReviewedHigh-Resolution Epitope Mapping of hGH-Receptor Interactions by Alanine-Scanning Mutagenesis SYSTEMATIC REPLACEMENT OF SEGMENTS (7 to 30 residues in length) of human growth hormone (hGH) with sequences derived from...
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From:Townsend Letter for Doctors and Patients (Issue 219) Peer-ReviewedDevelopments in science and the marketplace, along with recurrent questions about safety and efficacy have taken a toll on wellness products. This is for a good reason. People get hurt or die when safety and efficacy...
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From:PLoS ONE (Vol. 9, Issue 10) Peer-ReviewedTwo knockout mouse models for the autism candidate gene Neurobeachin (Nbea) have been generated independently. Although both models have similar phenotypes, one striking difference is the dwarf phenotype observed in the...
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From:Science (Vol. 273, Issue 5277) Peer-ReviewedSmall synthetic molecules termed growth hormone secretagogues (GHSs) act on the pituitary gland and the hypothalamus to stimulate and amplify pulsatile growth hormone (GH) release. A heterotrimeric GTP-binding protein (G...
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From:Stem Cells InternationalPeer-ReviewedMesenchymal stromal cells (MSCs) are promising candidates for regenerative medicine because of their multipotency, immuneprivilege, and paracrine properties including the potential to promote angiogenesis. Accumulating...
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From:International Journal of EndocrinologyPeer-ReviewedAcromegaly is caused by hypersecretion of growth hormone (GH) and consequently of insulin-like growth factor-I (IGF-1) due to pituitary tumor. Other causes, such as increased growth-hormone releasing hormone (GHRH)...
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From:Journal of the American Dietetic Association (Vol. 93, Issue 2) Peer-ReviewedAn analysis of recombinant proteins, bovine somatotropin (bST) and porcine somatotropin (pST), was undertaken to determine their safe and effective use among consumers. The benefits of integrating such technology in...
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From:Science (Vol. 273, Issue 5277) Peer-ReviewedResearchers have cloned the receptor that regulates the release of growth hormone, confirming that a route in addition to the growth hormone release peptide (GHRP) exists for the regulation of growth hormone. The next...
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From:Neural Regeneration Research (Vol. 10, Issue 8) Peer-ReviewedByline: Jin-Young. Chung, Jun-Sang. Sunwoo, Min-Wook. Kim, Manho. Kim Human growth hormone (GH) is a single-chain polypeptide of 191 amino acids that is involved in the regulation of various physiological processes,...
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From:PLoS ONE (Vol. 10, Issue 8) Peer-ReviewedThe Nestin-Cre driver mouse line has mild hypopituitarism, reduced body weight, a metabolic phenotype and reduced anxiety. Although several causes have been suggested, a comprehensive explanation is still lacking. In...
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From:PLoS ONE (Vol. 4, Issue 2) Peer-ReviewedMutations in the gene for growth hormone releasing hormone receptor (GHRHR) cause isolated growth hormone deficiency (IGHD) but this gene has not been found to affect normal variation in height. We performed a whole...
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From:International Journal of Endocrinology (Vol. 2022) Peer-ReviewedBackground. Arginine (ARG) can modulate growth hormone (GH) release by suppressing its endogenous inhibitory regulator, somatostatin. ARG also induces the release of the GH-releasing hormone (GHRH). This study aims to...
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From:Multinational Monitor (Vol. 16, Issue 9) Peer-ReviewedCancer researcher Dr. George Tritsch has recently published a paper which links milk from cows treated with bovine growth hormone (BGH) to cancer. Tritsch's conclusions were drawn from a recent study which showed that...
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From:Journal of Healthcare Engineering (Vol. 2017) Peer-ReviewedThe aim of this study was to quantify the contributions of lower extremity joint torques and the mechanical power of lower extremity muscle groups to further elucidate the loadings on hamstring and the mechanics of its...
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From:PLoS ONE (Vol. 10, Issue 3) Peer-ReviewedIn this study the effects of photoperiod and diet, and their interaction, were examined for their effects on growth and body composition in juvenile F344 rats over a 4-week period. On long (16L:8D), relative to short...