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    Academic Journals

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• Correction: Identification of OmpR-Family Response Regulators Interacting with Thioredoxin in the Cyanobacterium Synechocystis sp. PCC 6803

  Authors:Taro Kadowaki, Yoshitaka Nishiyama, Toru Hisabori, and Yukako HiharaFrom:PLoS ONE (Vol. 10, Issue 4) Peer-Reviewed

  Apr. 13, 2015138 words Brief article, Corre... 960LAuthor(s): Taro Kadowaki, Yoshitaka Nishiyama, Toru Hisabori, Yukako Hihara There is an error in the fifth sentence of the Abstract: "RpaB (Slr0946)" should be "RpaB (Slr0947)." The correct sentence is: Although...

• NADPH oxidase-induced NALP3 inflammasome activation is driven by thioredoxin-interacting protein which contributes to podocyte injury in hyperglycemia

  Authors:Pan Gao, Fang-Fang He, Hui Tang, Chun-Tao Lei, Shan Chen, Xian-Fang Meng, et al.From:Journal of Diabetes Research (Vol. 2015) Peer-Reviewed

  Annual 20154,523 words Article 1370LDiabetic nephropathy (DN) is one of the major causes of end-stage renal disease, and previously we demonstrated that NALP3 inflammasome was involved in the pathogenesis of DN. Here we investigated the mechanisms of...

• AMP-Activated Protein Kinase (AMPK) Mediates Nutrient Regulation of Thioredoxin-Interacting Protein (TXNIP) in Pancreatic Beta-Cells

  Authors:Maayan Shaked, Mali Ketzinel-Gilad, Erol Cerasi, Nurit Kaiser, and Gil LeibowitzFrom:PLoS ONE (Vol. 6, Issue 12) Peer-Reviewed

  Dec. 14, 20117,737 words Article 1390LThioredoxin-interacting protein (TXNIP) regulates critical biological processes including inflammation, stress and apoptosis. TXNIP is upregulated by glucose and is a critical mediator of hyperglycemia-induced beta-cell...

• Methylselenol Formed by Spontaneous Methylation of Selenide Is a Superior Selenium Substrate to the Thioredoxin and Glutaredoxin Systems

  Authors:Aristi P. Fernandes, Marita Wallenberg, Valentina Gandin, Sougat Misra, Francesco Tisato, Cristina Marzano, et al.From:PLoS ONE (Vol. 7, Issue 11) Peer-Reviewed

  Nov. 30, 20127,871 words Article 1470LNaturally occurring selenium compounds like selenite and selenodiglutathione are metabolized to selenide in plants and animals. This highly reactive form of selenium can undergo methylation and form monomethylated and...

• Snapshots of DsbA in action: detection of proteins in the process of oxidative folding

  Authors:Hiroshi Kadokura, Hongping Tian, Thomas Zander, James C.A. Bardwell, and Jon BeckwithFrom:Science (Vol. 303, Issue 5657) Peer-Reviewed

  Jan. 23, 20042,592 words Article 1430LDsbA, a thioredoxin superfamily member, introduces disulfide bonds into newly translocated proteins. This process is thought to occur via formation of mixed disulfide complexes between DsbA and its substrates. However,...

• Mode of action and membrane specificity of the antimicrobial peptide snakin-2

  Authors:Vera Herbel and Michael WinkFrom:PeerJ (Vol. 4) Peer-Reviewed

  May 10, 20165,167 words Article 1430LAntimicrobial peptides (AMPs) are a diverse group of short, cationic peptides which are naturally occurring molecules in the first-line defense of most living organisms. They represent promising candidates for the...

• Novel Potential Interacting Partners of Fibronectin in Spontaneous Animal Model of Interstitial Cystitis

  Authors:Gudrun Treutlein, Roswitha Dorsch, Kerstin N. Euler, Stefanie M. Hauck, Barbara Amann, Katrin Hartmann, et al.From:PLoS ONE (Vol. 7, Issue 12) Peer-Reviewed

  Dec. 7, 20128,486 words Article 1560LAuthor(s): Gudrun Treutlein 1 , Roswitha Dorsch 1 , Kerstin N. Euler 2 , Stefanie M. Hauck 3 , Barbara Amann 2 , Katrin Hartmann 1 , Cornelia A. Deeg 2 , * Introduction Feline idiopathic cystitis (FIC), a common...

• The Genome-Wide Early Temporal Response of Saccharomyces cerevisiae to Oxidative Stress Induced by Cumene Hydroperoxide

  From:PLoS ONE (Vol. 8, Issue 9) Peer-Reviewed

  Sept. 20, 201310,411 words Article 1450LIntroduction Several processes expose cells to reactive oxygen species (ROS) that cause severe damage to proteins, DNA and lipids, impairing cell function. Mitochondrial respiration is a major contributor to...

• CP-154,526 Modifies CREB Phosphorylation and Thioredoxin-1 Expression in the Dentate Gyrus following Morphine-Induced Conditioned Place Preference

  Authors:Juan-Antonio Garcia-Carmona, Daymi M. Camejo, Pilar Almela, Ana Jimenez, Maria-Victoria Milanes, Francisca Sevilla, et al.From:PLoS ONE (Vol. 10, Issue 8) Peer-Reviewed

  Aug. 27, 20158,084 words Report 1390LCorticotropin-releasing factor (CRF) acts as neuro-regulator of the behavioral and emotional integration of environmental and endogenous stimuli associated with drug dependence. Thioredoxin-1 (Trx-1) is a functional...

• Enhancement of Auranofin-Induced Apoptosis in MCF-7 Human Breast Cells by Selenocystine, a Synergistic Inhibitor of Thioredoxin Reductase

  Authors:Chaoran Liu, Zhong Liu, Meng Li, Xiaoling Li, Yum-Shing Wong, Sai-Ming Ngai, et al.From:PLoS ONE (Vol. 8, Issue 1) Peer-Reviewed

  Jan. 14, 20139,247 words Article 1470LThioredoxin system plays an important role in regulation of intracellular redox balance and various signaling pathways. Thioredoxin reductase (TrxR) is overexpressed in many cancer cells and has been identified as a...

• Possible Involvement of Nitric Oxide and Reactive Oxygen Species in Glucose Deprivation-Induced Activation of Transcription Factor Rst2

  From:PLoS ONE (Vol. 8, Issue 10) Peer-Reviewed

  Oct. 14, 20134,492 words Article 1310LGlucose is one of the most important sources of cellular nutrition and glucose deprivation induces various cellular responses. In Schizosaccharomyces pombe, zinc finger protein Rst2 is activated upon glucose...

• The N-Terminus of GalE Induces tmRNA Activity in Escherichia coli

  Authors:Zachary C. Ruhe and Christopher S. HayesFrom:PLoS ONE (Vol. 5, Issue 12) Peer-Reviewed

  Dec. 7, 20108,807 words Article 1510LBackground The tmRNA quality control system recognizes stalled translation complexes and facilitates ribosome recycling in a process termed 'ribosome rescue'. During ribosome rescue, nascent chains are tagged with...

• JS-K, a Nitric Oxide Prodrug, Has Enhanced Cytotoxicity in Colon Cancer Cells with Knockdown of Thioredoxin Reductase 1

  Authors:Kornelia Edes, Pamela Cassidy, Paul J. Shami, and Philip J. MoosFrom:PLoS ONE (Vol. 5, Issue 1) Peer-Reviewed

  Jan. 20, 20106,199 words Article 1510LBackground The selenoenzyme thioredoxin reductase 1 has a complex role relating to cell growth. It is induced as a component of the cellular response to potentially mutagenic oxidants, but also appears to provide...

• The Redox Sensor TXNL1 Plays a Regulatory Role in Fluid Phase Endocytosis

  Authors:Michela Felberbaum-Corti, Etienne Morel, Valeria Cavalli, Francis Vilbois, and Jean GruenbergFrom:PLoS ONE (Vol. 2, Issue 11) Peer-Reviewed

  Nov. 7, 20076,430 words Article 1500LBackground Small GTPases of the Rab family can cycle between a GTP- and a GDP-bound state and also between membrane and cytosol. The latter cycle is mediated by the Guanine Nucleotide Dissociation Inhibitor GDI,...

• Depletion of Plasmodium berghei Plasmoredoxin Reveals a Non-Essential Role for Life Cycle Progression of the Malaria Parasite

  Authors:Kathrin Buchholz, Stefan Rahlfs, R. Heiner Schirmer, Katja Becker, and Kai MatuschewskiFrom:PLoS ONE (Vol. 3, Issue 6) Peer-Reviewed

  June 25, 20085,323 words Article 1450LProliferation of the pathogenic Plasmodium asexual blood stages in host erythrocytes requires an exquisite capacity to protect the malaria parasite against oxidative stress. This function is achieved by a complex...

• Deep-Sea Water Containing Selenium Provides Intestinal Protection against Duodenal Ulcers through the Upregulation of Bcl-2 and Thioredoxin Reductase 1

  Authors:Chih-Ching Yang, Chien-An Yao, Yi-Ruu Lin, Jyh-Chin Yang, and Chiang-Ting ChienFrom:PLoS ONE (Vol. 9, Issue 7) Peer-Reviewed

  July 1, 20148,506 words Article 1540LDeep-sea water (DSW), which is rich in micronutrients and minerals and with antioxidant and anti-inflammatory qualities, may be developed as marine drugs to provide intestinal protection against duodenal ulcers. We...

• Stromal Response to Prostate Cancer: Nanotechnology-Based Detection of Thioredoxin-Interacting Protein Partners Distinguishes Prostate Cancer Associated Stroma from That of Benign Prostatic Hyperplasia

  Authors:Elizabeth Singer, Jennifer Linehan, Gail Babilonia, S. Ashraf Imam, David Smith, Sofia Loera, et al.From:PLoS ONE (Vol. 8, Issue 6) Peer-Reviewed

  June 6, 20134,618 words Article 1640LHistological staining of reactive stroma has been shown to be a predictor of biochemical recurrence in prostate cancer, however, molecular markers of the stromal response to prostate cancer have not yet been fully...

• Thioredoxin-Mimetic-Peptides Protect Cognitive Function after Mild Traumatic Brain Injury (mTBI)

  Authors:Renana Baratz-Goldstein, Hanna Deselms, Leore Raphael Heim, Lena Khomski, Barry J. Hoffer, Daphne Atlas, et al.From:PLoS ONE (Vol. 11, Issue 6) Peer-Reviewed

  June 10, 20167,279 words Report 1380LMild traumatic brain injury (mTBI) is recognized as a common injury among children, sportsmen, and elderly population. mTBI lacks visible objective structural brain damage but patients frequently suffer from...

• The Influence of Reactive Oxygen Species in the Immune System and Pathogenesis of Multiple Sclerosis.

  Authors:Mohammad javad Tavassolifar, Mohammad Vodjgani, Zahra Salehi, and Maryam IzadFrom:Autoimmune Diseases (Vol. 2020) Peer-Reviewed

  July 31, 202010,770 words Article 1410LMultiple roles have been indicated for reactive oxygen species (ROS) in the immune system in recent years. ROS have been extensively studied due to their ability to damage DNA and other subcellular structures....

• Differential Expression Profiles in the Midgut of Triatoma infestans Infected with Trypanosoma cruzi

  Authors:Diego S. Buarque, Gloria R. C. Braz, Rafael M. Martins, Anita M. Tanaka-Azevedo, Cicera M. Gomes, Felipe A. A. Oliveira, et al.From:PLoS ONE (Vol. 8, Issue 5) Peer-Reviewed

  May 2, 20136,341 words Article 1430LAuthor(s): Diego S. Buarque 1, Glória R. C. Braz 2, Rafael M. Martins 3, Anita M. Tanaka-Azevedo 4, Cícera M. Gomes 4, Felipe A. A. Oliveira 1, Sergio Schenkman 5, Aparecida S. Tanaka 1,* Introduction Parasitic...