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    Academic Journals

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• Cell-specific gene promoters are marked by broader spans of H3K4me3 and are associated with robust gene expression patterns

  Authors:Duygu Ucar and Dashzeveg BayarsaihanFrom:Epigenomics (Vol. 7, Issue 2) Peer-Reviewed

  Apr. 20151,794 words Report 1860LAuthor(s): Duygu Ucar aff1 , Dashzeveg Bayarsaihan aff2 Keywords: enhancers; epigenetic regulation; H3K4me3; histone methylation Genome-wide histone modification profiles contain precious information hidden in...

• Spatial reconstruction of single-cell gene expression data

  Authors:Rahul Satija, Jeffrey A. Farrell, David Gennert, Alexander F. Schier, and Aviv RegevFrom:Nature Biotechnology (Vol. 33, Issue 5) Peer-Reviewed

  May 201513,951 words Report 1550LSpatial localization is a key determinant of cellular fate and behavior, but methods for spatially resolved, transcriptome-wide gene expression profiling across complex tissues are lacking. RNA staining methods assay...

• Correction: A Complete Set of Nascent Transcription Rates for Yeast Genes

  From:PLoS ONE (Vol. 9, Issue 12) Peer-Reviewed

  Dec. 5, 2014199 words Brief article, Corre... 1290LAuthor(s): The PLOS ONE Staff There is an error in Supporting Information Table S3. The headings in columns G and H are interchanged. Please view the corrected table below. Supporting Information Table S3...

• Novel viral evasion tactic found from influenza virus H3N2

  Authors:Dongsheng Li, Vincent Cutillas, and Ting WeiFrom:Future Virology (Vol. 7, Issue 7)

  July 20121,694 words Article 1610LAuthor(s): Dongsheng Li 1 , Vincent Cutillas 1 2 , Ting Wei [*] 3 Keywords * evasion tactic; histone H3 protein; hPAF1C Summary of methods & results Marazzi et al. found that NS1 from influenza virus...

• At the forefront of retrovirology research: Frontiers of Retrovirology

  Authors:Tamara Bar-Magen, Richard D Sloan, and Mark A WainbergFrom:HIV Therapy (Vol. 4, Issue 1)

  Jan. 20101,304 words Article Author(s): Tamara Bar-Magen 1 , Richard D Sloan 1 , Mark A Wainberg [[dagger]] 1 Restriction factors & replication A major theme was cellular factors that are responsible for regulating and restricting viral...

• Expression of transcription factor AP-2 in colorectal adenomas and adenocarcinomas; comparison of immunohistochemistry and in situ hybridisation

  Authors:K M Ropponen, J K Kellokoski, R T Pirinen, K I Moisia, M J Eskelinen, E M Alhava, et al.From:Journal of Clinical Pathology (Vol. 54, Issue 7) Peer-Reviewed

  July 20013,665 words Article Abstract Aims--To investigate whether the three different AP-2 isoforms are expressed differently in colorectal adenomas and carcinomas. Methods--The study comprised 43 randomly selected patients diagnosed and...

• Survival Factors and Apoptosis

  Author:TOM HOLLONFrom:The Scientist (Vol. 15, Issue 7) Peer-Reviewed

  Apr. 2, 2001736 words Brief article Researchers show how signals block death gene transcription factor Cell life depends on stringent repression of apoptosis, or programmed cell death. Repressing transcription of cell death genes is one way of...

• The myoD gene family: nodal point during specification of the muscle cell lineage

  Authors:Harold Weintraub, Robert Davis, Stephen Tapscott, Matthew Thayer, Michael Krause, Robert Benezra, et al.From:Science (Vol. 251, Issue 4995) Peer-Reviewed

  Feb. 15, 19917,088 words Article THE MYOD GENE IS CAPABLE OF ACTIVATING PREVIOUSLY silent muscle-specific genes when introduced into a large variety of differentiated cell types with a viral long terminal repeat (LTR) used to promote constitutive...

• Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1

  Authors:Dirk Bohmann, Timothy J. Bos, Arie Admon, Tetsuji Nishimura, Peter K. Vogt, and Robert TjianFrom:Science (Vol. 238, Issue 4832) Peer-Reviewed

  Dec. 4, 19876,650 words Article Human Proto-Oncogene c-jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1 AGROWING NUMBER OF VIRAL AND CELLULAR GENES HAVE been identified as potential cancer...

• Consequences of replication fork movement through transcription units in vivo

  Author:Sarah FrenchFrom:Science (Vol. 258, Issue 5086) Peer-Reviewed

  Nov. 20, 19922,875 words Article To examine the basis for the evolutionary selection for codirectionality of replication and transcription in Escherichia coli, electron microscopy was used to visualize replication from an inducible ColE1 replication...

• Modulation of the dimerization of a transcriptional antiterminator protein by phosphorylation

  Authors:Orna Amster-Choder and Andrew WrightFrom:Science (Vol. 257, Issue 5075) Peer-Reviewed

  Sept. 4, 19922,141 words Article The transcriptional antiterminator protein BglG inhibits transcription termination of the bgl operon in Escherichia coli when it is in the nonphosphorylated state. The BglG protein is now shown to exist in two...

• An origin of DNA replication and a transcription silencer require a common element

  Authors:David H. Rivier and Jasper RineFrom:Science (Vol. 256, Issue 5057) Peer-Reviewed

  May 1, 19923,855 words Article A eukaryotic chromosomal origin of replication was identified in the yeast Saccharomyces cerevisiae. By several criteria, including map position, deletion analysis, and a synthetic form of saturation mutagenesis, the...

• Identification of a naturally occurring transforming variant of the p65 subunit of NF-kappa-B

  Authors:Ramaswamy Narayanan, John F. Klement, Steven M. Ruben, Kimberly A. Higgins, and Craig A. RosenFrom:Science (Vol. 256, Issue 5055) Peer-Reviewed

  Apr. 17, 19922,050 words Article Transcription factor NF-kB comprises two proteins, p50 and p65, that have sequence similarity to the v-rel oncogene. In primary hematopoietic cell populations an alternatively spliced form of NF-kB p65 mRNA was observed...

• Effect of sodium salicylate on the human heat shock response

  Authors:Donald A. Jurivich, Lea Sistonen, Roger A. Kroes, and Richard I. MorimotoFrom:Science (Vol. 255, Issue 5049) Peer-Reviewed

  Mar. 6, 19921,813 words Article Sodium salicylate, an anti-inflammatory agent, was examined for its effects on the heat shock response in cultured human cells. Salicylate activation of DNA binding by the heat shock transcription factor (HSF) was...

• Crystal structure of a CAP-DNA complex: the DNA is bent by 90 degrees

  Authors:Steve C. Schultz, George C. Shields, and Thomas A. SteitzFrom:Science (Vol. 253, Issue 5023) Peer-Reviewed

  Aug. 30, 19915,970 words Article SEVERE PROTEIN-INDUCED BENDING of DUPLEX DNA HAS been demonstrated by a variety of biochemical and biophysical techniques [1-10], including a low-resolution crystal structure of the nucleosome core particle [10]....

• Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation

  Authors:Jagan M.R. Pongubala, Charles Van Beveren, Sujatha Nagulapalli, Michael J. Klemsz, Scott R. McKercher, Richard A. Maki, et al.From:Science (Vol. 259, Issue 5101) Peer-Reviewed

  Mar. 12, 19932,953 words Article PU.1 recruits the binding of a second B cell--restricted nuclear factor, NF-EM5, to a DNA site in the immunoglobulin [Kappa] 3' enhancer. DNA binding by NF-EM5 requires a protein-protein interaction with PU.1 and...

• A role for the transcription factors Mbp1 and Swi4 in progression from G1 to S phase

  Authors:Christian Koch, Thomas Moll, Manfred Neuberg, Horst Ahorn, and Kim NasmythFrom:Science (Vol. 261, Issue 5128) Peer-Reviewed

  Sept. 17, 19934,760 words Article In budding yeast genes that encode G1 cyclins and proteins involved in DNA synthesis are transcriptionally activated in late G1. A transcription factor, called SBF, is composed of Swi4 and Swi6 proteins and activates...

• Function of a bacterial activator protein that binds to transcriptional enhancers

  Authors:David L. Popham, Daniel Szeto, John Keener, and Sydney KustuFrom:Science (Vol. 243, Issue 4891) Peer-Reviewed

  Feb. 3, 19893,429 words Article Function of a Bacterial Activator Protein That Binds to Transcriptional Enhancers TRANSCRIPTIONAL ENHANCER SEQUENCES FOR EUKARYOTIC genes are binding sites for regulatory proteins. Enhancers lie at a distance from...

• Oxidation-reduction and the molecular mechanism of a regulatory RNA-protein interaction

  Authors:Matthias W. Hentze, Tracey A. Rouault, Joe B. Harford, and Richard D. KlausnerFrom:Science (Vol. 244, Issue 4902) Peer-Reviewed

  Apr. 21, 19891,836 words Article Oxidation-Reduction and the Molecular Mechanism of a Regulatory RNA-Protein Interaction THE FORMATION OF SPECIFIC NUcleic acid-protein complexes has been shown to play a key role in DNA transcription, pre-mRNA...

• A potent GAL4 derivative activates transcription at a distance in vitro

  Authors:Michael Carey, Janet Leatherwood, and Mark PtashneFrom:Science (Vol. 247, Issue 4943) Peer-Reviewed

  Feb. 9, 19901,474 words Article A Potent GAL4 Derivative Activates Transcription at a Distance in Vitro GAL4 IS A TRANSCRIPTIONAL ACTIvator found in the yeast Saccharomyces cerevisiae [1]. The 881-amino acid protein binds as dimers to 17-bp dyad...