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From:Egyptian Journal of Dermatology and Venerology (Vol. 33, Issue 1) Peer-ReviewedByline: Mohammed. Elzorkany, Naglaa. Ahmed, Mohamed. Kamel, Neama. Hussein, Marwa. Embarak Background Peyronie’s disease (PD) is an acquired disorder of the penile tunica albuginea. PD may manifest in the form...
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From:Biochemistry and Cell Biology (Vol. 93, Issue 2) Peer-ReviewedAbstract: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal scarring lung disease of unknown etiology,characterized by changes in microRNA expression. Activation of transforming growth factor...
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From:PVRI Review (Vol. 1, Issue 1) Peer-ReviewedByline: Nicholas. Morrell The identification of heterozygous germline mutations in the bone morphogenetic protein type II receptor (BMPR-II), a receptor for the transforming growth factor-[sz] (TGF-[sz]) superfamily,...
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From:Regenerative Medicine (Vol. 5, Issue 5)Author(s): Sandra Strassburg 1 , Stephen M Richardson 1 , Anthony J Freemont 1 , Judith A Hoyland [[dagger]] 2 KEYWORDS: co-culture; intervertebral disc regeneration; mesenchymal stem cells; nucleus pulposus...
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From:Biomarkers in Medicine (Vol. 5, Issue 6) Peer-ReviewedAuthor(s): Nataša TodorovicÄ-RakovicÄ [**] 2 , Jelena MilovanovicÄ 1 , Dragica NikolicÄ-VukosavljevicÄ 1 KEYWORDS : [beta]β-glycan; cancer; endoglin; TGF-[beta]β The TGF-[beta]β family are...
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From:Gut (Vol. 53, Issue 4) Peer-ReviewedBackground: The renin angiotensin system (RAS) and transforming growth factor beta-1 (TGF[beta]-1) are responsible for fibroproliferative changes which can potentially be reduced by pharmacological intervention....
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From:Science (Vol. 263, Issue 5143) Peer-ReviewedTransforming growth factor beta (TGF-[beta]) is a multifunctional factor that regulates many aspects of cellular functions. TGF-[beta] signals through a heteromeric complex of the type I and type II TGF-[beta]...
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From:PLoS ONE (Vol. 7, Issue 2) Peer-ReviewedAuthor(s): Joel Gaston 1 , Beatriz Quinchia Rios 2 , Rebecca Bartlett 2 , Craig Berchtold 2 , Susan L. Thibeault 1 , 2 , * Introduction The unique mechano-environment of vocal fold mucosa includes its ability to...
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From:PLoS ONE (Vol. 8, Issue 10) Peer-ReviewedAuthor(s): Nasrine Bendjilali 1, Helen Kim 1,2,3, Shantel Weinsheimer 1, Diana E. Guo 1, Pui-Yan Kwok 2,4, Jonathan G. Zaroff 5, Stephen Sidney 5, Michael T. Lawton 6, Charles E. McCulloch 3, Bobby P. C. Koeleman 7,...
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From:PLoS ONE (Vol. 9, Issue 3) Peer-ReviewedAuthor(s): The PLOS ONE Staff Notice of Republication This article was republished on February 28, 2014, to correct capitalization in the title. The originally published, uncorrected article and the republished,...
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From:PLoS ONE (Vol. 8, Issue 4) Peer-ReviewedAuthor(s): Martin N. Nakatsu 1, Lily Vartanyan 1, Daniel M. Vu 1, Madelena Y. Ng 1, Xinmin Li 2, Sophie X. Deng 1,* Introduction The preservation of corneal transparency and maintenance of the corneal epithelium...
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From:PLoS ONE (Vol. 8, Issue 11) Peer-ReviewedAuthor(s): Tanvi Saxena 1, Bhavna Tandon 1, Shivani Sharma 1, Shibu Chameettachal 2, Pratima Ray 3, Alok R. Ray 4,5, Ritu Kulshreshtha 1,* Introduction Chikungunya virus (CHIKV) is an enveloped, positive sense,...
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From:Nature Medicine (Vol. 22, Issue 6) Peer-ReviewedAuthor(s): Takuro Saito [1, 2]; Hiroyoshi Nishikawa (corresponding author) [1]; Hisashi Wada [2, 3]; Yuji Nagano [4]; Daisuke Sugiyama [1]; Koji Atarashi [4]; Yuka Maeda [1]; Masahide Hamaguchi [1]; Naganari Ohkura [1];...
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From:Journal of Diabetes Research (Vol. 2016) Peer-ReviewedThe increase in the prevalence of diabetes mellitus (DM) and the secondary kidney damage produces diabetic nephropathy (DN). Early nephropathy is defined as the presence of microalbuminuria (30-300 mg/day), including...
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From:Journal of Diabetes Research (Vol. 2016) Peer-ReviewedObjective. To investigate the expression of miR-192 and its significance in diabetic nephropathy (DN) patients. Methods. 464 patients with type 2 diabetes mellitus (T2DM) were divided into normal albuminuria group (NA,...
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From:Indian Journal of Dental Advancements (Vol. 8, Issue 4) Peer-ReviewedHemangiomas are considered to be benign tumors of infancy which show a rapid growth phase marked by endothelial cell proliferation, followed by gradual involution. On the other hand, vascular malformations are...
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From:BioMed Research InternationalPeer-ReviewedTGF-[[beta].sub.1] has been recognized as a key mediator in DN. This study aimed to observe the effects of low-protein diets supplemented with ketoacid on mRNA and protein expression of TGF-[beta] and T[beta]RI and t...
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From:Journal of Clinical Investigation (Vol. 124, Issue 2) Peer-ReviewedDuring bone resorption, abundant factors previously buried in the bone matrix are released into the bone marrow microenvironment, which results in recruitment and differentiation of bone marrow mesenchymal stem cells...
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From:Oxidative Medicine and Cellular Longevity (Vol. 2016) Peer-ReviewedBackground. Cardiovascular morbidity and mortality are very high in patients with chronic kidney disease (CKD). The purpose of this study is to evaluate the impact of continuous erythropoietin receptor activator (CERA)...
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From:Diabetes (Vol. 63, Issue 1) Peer-ReviewedAlthough growth differentiation factor-5 (GDF5) has been implicated in skeletal development and joint morphogenesis in mammals, little is known about its functionality in adipogenesis and energy homeostasis. Here, we...