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    Academic Journals

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• Paeonia lactiflora Enhances the Adhesion of Trophoblast to the Endometrium via Induction of Leukemia Inhibitory Factor Expression

  Authors:Hee-Jung Choi, Tae-Wook Chung, Mi-Ju Park, Kyu Sup Lee, Youngjin Yoon, Hyung Sik Kim, et al.From:PLoS ONE (Vol. 11, Issue 2) Peer-Reviewed

  Feb. 3, 20167,009 words Report 1350LIn the present study, we investigated the role of Paeonia lactiflora Pall. extract on embryo implantation in vitro and in vivo. A polysaccharides depleted-water extract of P. lactiflora (PL-PP) increased LIF expression...

• Impact of vitamin D and vitamin D receptor on the trophoblast survival capacity in preeclampsia

  Authors:Martina Hutabarat, Noroyono Wibowo, Barbara Obermayer-Pietsch, and Berthold HuppertzFrom:PLoS ONE (Vol. 13, Issue 11) Peer-Reviewed

  Nov. 8, 20185,828 words Report 1680LBackground Preeclampsia and intra-uterine growth restriction (IUGR) are major health problems during pregnancy affecting both mother and child. Defective placental development and failure of trophoblast...

• Bone Marrow Mesenchymal Stem Cells Attenuate Mitochondria Damage Induced by Hypoxia in Mouse Trophoblasts

  Authors:Lingjuan Wang, Xiaoyan Xu, Lina Kang, and Wenpei XiangFrom:PLoS ONE (Vol. 11, Issue 4) Peer-Reviewed

  Apr. 21, 20164,949 words Report 1540LObjective We aimed to observe the change of mitochondrial function and structure as well as the cell function induced by hypoxia in mouse trophoblasts, and moreover, to validate the restoration of these changes after...

• Bisphenol S and Epidermal Growth Factor Receptor Signaling in Human Placental Cytotrophoblasts.

  Authors:Elvis Ticiani, Jeremy Gingrich, Yong Pu, Mathew Vettathu, Jacquelyn Davis, Denny Martin, et al.From:Environmental Health Perspectives (Vol. 129, Issue 2) Peer-Reviewed

  Feb. 20218,629 words Report 1350LBackground: Bisphenol S (BPS) is an endocrine-disrupting chemical and the second most abundant bisphenol detected in humans. In vivo BPS exposure leads to reduced binucleate cell number in the ovine placenta. Binucleate...

• Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino acid transport in human primary trophoblast cells

  Authors:Helen N. Jones, Thomas Jansson, and Theresa L. PowellFrom:Diabetes (Vol. 59, Issue 5) Peer-Reviewed

  May 20106,874 words Report 1520LOBJECTIVE--Maternal adiponectin levels are reduced and placental nutrient transporters are upregulated in obesity and gestational diabetes mellitus; however, the effects of adiponectin on placental function are unknown....

• CMV Trophoblasts May Play a Role in Maternofetal Transmission

  From:Herpes Viruses Weekly

  Oct. 5, 1998486 words Article Trophoblast cells can be permissively and productively infected by human cytomegalovirus, study results show. G. Halwachs-Baumann, University of Graz, Germany, and colleagues permissively infected human trophoblast...

• Trophoblast L-selectin--mediated adhesion at the maternal-fetal interface. (Reports)

  Authors:Olga D. Genbacev, Akraporn Prakobphol, Russell A. Foulk, Ana R. Krtolica, Dusko Ilic, Mark S. Singer, et al.From:Science (Vol. 299, Issue 5605) Peer-Reviewed

  Jan. 17, 20032,441 words Article Trophoblast adhesion to the uterine wall is the requisite first step of implantation and, subsequently, placentation. At the maternal-fetal interface, we investigated the expression of selectin adhesion systems that...

• The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification.

  Authors:Mona Abed, Erik Verschueren, Hanna Budayeva, Peter Liu, Donald S. Kirkpatrick, Rohit Reja, et al.From:PLoS ONE (Vol. 14, Issue 4) Peer-Reviewed

  Apr. 5, 20197,829 words Report 1470LPeg10 (paternally expressed gene 10) is an imprinted gene that is essential for placental development. It is thought to derive from a Ty3-gyspy LTR (long terminal repeat) retrotransposon and retains Gag and Pol-like...

• Prenatal diagnostic test uses endocervical mucus

  Author:Kate JohnsonFrom:Family Practice News (Vol. 35, Issue 16)

  Aug. 15, 2005329 words Brief article COPENHAGEN -- An investigational prenatal diagnostic test that uses fetal cells taken from maternal endocervical mucus could offer all the advantages of chorionic villus sampling, according to a study sponsored by...

• Raman Spectroscopy characterization extracellular vesicles from bovine placenta and peripheral blood mononuclear cells

  Authors:Han Zhang, Ana Caroline Silva, Wei Zhang, Heloisa Rutigliano, and Anhong ZhouFrom:PLoS ONE (Vol. 15, Issue 7) Peer-Reviewed

  July 2, 20206,074 words Report 1570LAuthor(s): Han Zhang 1, Ana Caroline Silva 2, Wei Zhang 1, Heloisa Rutigliano 2,*, Anhong Zhou 1,* 1 Introduction Extracellular vesicles (EVs) are phospholipid membrane complexes that contain proteins, lipids, and...

• PM10 Alters Trophoblast Cell Function and Modulates miR-125b-5p Expression.

  Authors:Wittaya Chaiwangyen, Komsak Pintha, Payungsak Tantipaiboonwong, Piyawan Nuntaboon, Orawan Khantamat, and Francisco Lázaro Pereira de SousaFrom:BioMed Research International (Vol. 2022) Peer-Reviewed

  Jan. 7, 20228,491 words Report 1350LAir pollution is one of the largest global environmental health hazards that threaten premature mortality or morbidity. Particulate matter 10 (PM10) has been demonstrated to contribute to several human diseases via...

• Trophoblastic infiltration in tubal pregnancy evaluated by immunohistochemistry and correlation with variation of beta-human chorionic gonadotropin

  Authors:Danyelle Farias Ferreira, Julio Elito, Jr., Edward Araujo, Jr., Joao Norberto Stavale, Luiz Camano, and Antonio Fernandes MoronFrom:Pathology Research InternationalPeer-Reviewed

  Annual 20143,400 words Report 1560LObjective. To evaluate trophoblastic cell proliferation and angiogenesis in tubal pregnancy assessed by immunohistochemical study and their correlation with an average variation of [beta]-hCG in an interval of 48 hours...

• Interdependence of JAK-STAT and MAPK signaling pathways during EGF-mediated HTR-8/SVneo cell invasion

  Authors:Ankita Malik, Rahul Pal, and Satish Kumar GuptaFrom:PLoS ONE (Vol. 12, Issue 5) Peer-Reviewed

  May 25, 20177,883 words Report 1490LInvasion of trophoblast cells is spatio-temporally regulated by various cytokines and growth factors. In pregnancy, complications like preeclampsia, shallow invasion of trophoblast cells and low amounts of epidermal...

• Murine trophoblast-derived and pregnancy-associated exosome-enriched extracellular vesicle microRNAs: Implications for placenta driven effects on maternal physiology

  Authors:Adrianne L. Stefanski, Nadine Martinez, Lisa K. Peterson, Tiffany J. Callahan, Eric Treacy, Marisa Luck, et al.From:PLoS ONE (Vol. 14, Issue 2) Peer-Reviewed

  Feb. 7, 20198,634 words Report 1470LThe role of extracellular vesicles (EVs), specifically exosomes, in intercellular communication likely plays a key role in placental orchestration of pregnancy and maternal immune sensing of the fetus. While murine...

• Trophoblast organoids as a model for maternal-fetal interactions during human placentation

  Authors:Margherita Y. Turco, Lucy Gardner, Richard G. Kay, Russell S. Hamilton, Malwina Prater, Michael S. Hollinshead, et al.From:Nature (Vol. 564, Issue 7735) Peer-Reviewed

  Dec. 20188,185 words Report 1430LThe placenta is the extraembryonic organ that supports the fetus during intrauterine life. Although placental dysfunction results in major disorders of pregnancy with immediate and lifelong consequences for the mother...

• Time-dependent effect of oral morphine consumption on the development of cytotrophoblast and syncytiotrophoblasT cells of the placental layers during the three different periods of pregnancy in Wistar rats

  Authors:Leila Dehghani, Hedayat Sahraei, Rokhsareh Meamar, and Masoomeh KazemiFrom:Journal of Immunology Research (Vol. 2013) Peer-Reviewed

  Annual 20133,419 words Report 1490LPrevious studies have shown that morphine abuse during pregnancy cancause a delay in the development of the placenta and embryo and also bring about birth defects. The present study investigates the effect of the...

• Nik-related kinase regulates trophoblast proliferation and placental development by modulating AKT phosphorylation

  Authors:Yuka Morioka, Jin-Min Nam, and Takashi OhashiFrom:PLoS ONE (Vol. 12, Issue 2) Peer-Reviewed

  Feb. 2, 20179,529 words Report 1460LNik-related kinase (Nrk) is a Ser/Thr kinase and was initially discovered as a molecule that was predominantly detected in skeletal muscles during development. A recent study using Nrk-null mice suggested the importance...

• Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy

  Authors:Yujie Cui, Wei Wang, Ningzheng Dong, Jinglei Lou, Dinesh Kumar Srinivasan, Weiwei Cheng, et al.From:Nature (Vol. 484, Issue 7393) Peer-Reviewed

  Apr. 12, 20124,865 words Report 1340LIn pregnancy, trophoblast invasion and uterine spiral artery remodelling are important for lowering maternal vascular resistance and increasing uteroplacental blood flow. Impaired spiral artery remodelling has been...

• HELLP Babies link a novel lincRNA to the trophoblast cell cycle

  Authors:Marie van Dijk, Hari K. Thulluru, Joyce Mulders, Omar J. Michel, Ankie Poutsma, Sandra Windhorst, et al.From:Journal of Clinical Investigation (Vol. 122, Issue 11) Peer-Reviewed

  Nov. 20125,300 words Report 1350LThe HELLP syndrome is a pregnancy-associated disease inducing hemolysis, elevated liver enzymes, and low platelets in the mother. Although the HELLP symptoms occur in the third trimester in the mother, the origin of the...

• Initiation of a conserved trophectoderm program in human, cow and mouse embryos

  Authors:Claudia Gerri, Afshan McCarthy, Gregorio Alanis-Lobato, Andrej Demtschenko, Alexandre Bruneau, Sophie Loubersac, et al.From:Nature (Vol. 587, Issue 7834) Peer-Reviewed

  Nov. 19, 202013,151 words Report 1610LCurrent understandings of cell specification in early mammalian pre-implantation development are based mainly on mouse studies. The first lineage differentiation event occurs at the morula stage, with outer cells...