Search Results

• • 250 

    Academic Journals

  • Sort by: sorttype.publication.date.desc Newest sorttype.publication.date.asc Oldest sorttype.relevance Relevance

• In Vivo Imaging with Fluorescent Smart Probes to Assess Treatment Strategies for Acute Pancreatitis

  Authors:Abhiruchi Agarwal, Andreas Boettcher, Rainer Kneuer, Farid Sari-Sarraf, Adriana Donovan, Julian Woelcke, et al.From:PLoS ONE (Vol. 8, Issue 2) Peer-Reviewed

  Feb. 11, 20138,052 words Article 1380LBackground and Aims Endoprotease activation is a key step in acute pancreatitis and early inhibition of these enzymes may protect from organ damage. In vivo models commonly used to evaluate protease inhibitors...

• REDUCED NUMBER OF LUNG INFECTIONS REPORTED BY ANTITRYPSIN DEFICIENT PATIENTS RECEIVING PROLASTIN (ANTIPROTEASE) AUGMENTATION THERAPY

  Authors:Jack Lieberman, C Larsen, and C BarilFrom:Chest (Vol. 116, Issue 4) Peer-Reviewed

  Oct. 1999274 words Brief article Purpose: To determine patient opinion regarding the effect of AAT augmentation on incidence of lung infections. Methods: Patients with severe antitrypsin deficiency (PiZZ) who had been receiving Prolastin for 1-10...

• Trypsin-sensitive, rapid inactivation of a calcium-activated potassium channel

  Authors:Christopher R. Solaro and Christopher J. LingleFrom:Science (Vol. 257, Issue 5077) Peer-Reviewed

  Sept. 18, 19923,278 words Article Most calcium-activated potassium channels couple changes in intracellular calcium to membrane excitability by conducting a current with a probability that depends directly on submembrane calcium concentration. In rat...

• Age-Related Changes in the Retinal Pigment Epithelium (RPE)

  Authors:Xiaorong Gu, Nikolas J. Neric, John S. Crabb, John W. Crabb, Sanjoy K. Bhattacharya, Mary E. Rayborn, et al.From:PLoS ONE (Vol. 7, Issue 6) Peer-Reviewed

  June 11, 20127,053 words Article 1530LAuthor(s): Xiaorong Gu 1 , Nikolas J. Neric 1 , John S. Crabb 1 , John W. Crabb 1 , Sanjoy K. Bhattacharya 2 , Mary E. Rayborn 1 , Joe G. Hollyfield 1 , Vera L. Bonilha 1 , * Introduction The retinal pigment...

• Decidual-Secreted Factors Alter Invasive Trophoblast Membrane and Secreted Proteins Implying a Role for Decidual Cell Regulation of Placentation

  Authors:Ellen Melaleuca Menkhorst, Natalie Lane, Amy Louise Winship, Priscilla Li, Joanne Yap, Katie Meehan, et al.From:PLoS ONE (Vol. 7, Issue 2) Peer-Reviewed

  Feb. 16, 20128,171 words Article 1370LAuthor(s): Ellen Melaleuca Menkhorst, Natalie Lane, Amy Louise Winship, Priscilla Li, Joanne Yap, Katie Meehan, Adam Rainczuk, Andrew Stephens, Evdokia Dimitriadis * Introduction During the establishment of...

• Dysregulation of Protease and Protease Inhibitors in a Mouse Model of Human Pelvic Organ Prolapse

  Authors:Madhusudhan Budatha, Simone Silva, Teodoro Ignacio Montoya, Ayako Suzuki, Sheena Shah-Simpson, Cecilia Karin Wieslander, et al.From:PLoS ONE (Vol. 8, Issue 2) Peer-Reviewed

  Feb. 20, 20138,275 words Article 1440LAuthor(s): Madhusudhan Budatha 1 , Simone Silva 2 , Teodoro Ignacio Montoya 2 , Ayako Suzuki 3 , 4 , Sheena Shah-Simpson 1 , Cecilia Karin Wieslander 2 , Masashi Yanagisawa 3 , 4 , Ruth Ann Word 2 , * , Hiromi...

• Activity and Stability of Trypsin Immobilized onto Chitosan Magnetic Nanoparticles

  Authors:Jun Sun, Bin Xu, Yu Shi, Lin Yang, and Hai-le MaFrom:Advances in Materials Science and Engineering (Vol. 2017) Peer-Reviewed

  Annual 20175,463 words Article 1450LThe aim of this study was to develop a thermally and operationally stable trypsin through covalent immobilization onto chitosan magnetic nanoparticles ([Fe.sub.3][O.sub.4] @CTS). The successful preparation of the...

• Breakdown of Mucin as Barrier to Digestive Enzymes in the Ischemic Rat Small Intestine

  Authors:Marisol Chang, Tom Alsaigh, Erik B. Kistler, and Geert W. Schmid-SchonbeinFrom:PLoS ONE (Vol. 7, Issue 6) Peer-Reviewed

  June 29, 20127,430 words Article 1560LLoss of integrity of the epithelial/mucosal barrier in the small intestine has been associated with different pathologies that originate and/or develop in the gastrointestinal tract. We showed recently that mucin, the...

• Proteomic Analysis of the Extracellular Matrix Produced by Mesenchymal Stromal Cells: Implications for Cell Therapy Mechanism

  Authors:Adam Harvey, Ten-Yang Yen, Irina Aizman, Ciara Tate, and Casey CaseFrom:PLoS ONE (Vol. 8, Issue 11) Peer-Reviewed

  Nov. 14, 20137,499 words Article 1440LMesenchymal stromal cells (MSCs) transiently transfected with notch1 intracellular domain (NICD) are beneficial for neurological disorders as observed in several preclinical studies. Extracellular matrix (ECM) derived...

• Activation of Bt Protoxin Cry1Ac in Resistant and Susceptible Cotton Bollworm

  Authors:Jizhen Wei, Gemei Liang, Bingjie Wang, Feng Zhong, Lin Chen, Myint Myint Khaing, et al.From:PLoS ONE (Vol. 11, Issue 6) Peer-Reviewed

  June 3, 20166,399 words Report 1540LCrystalline (Cry) proteins from Bacillus thuringiensis (Bt) are used extensively for insect control in sprays and transgenic plants, but their efficacy is reduced by evolution of resistance in pests. Here we evaluated...

• An Aedes aegypti-associated fungus increases susceptibility to dengue virus by modulating gut trypsin activity

  Authors:Yesseinia I Anglero-Rodriguez, Octavio AC Talyuli, Benjamin J Blumberg, Seokyoung Kang, Celia Demby, Alicia Shields, et al.From:eLife (Vol. 6) Peer-Reviewed

  Dec. 5, 201711,760 words Article 1350LTransmission of dengue virus (DENV) requires successful completion of the infection cycle in the Aedes aegypti vector, which is initiated in the midgut tissue after ingestion of an infectious blood meal. While certain...

• Tyrosine Sulfation of Human Trypsin Steers S2' Subsite Selectivity towards Basic Amino Acids

  Authors:Andras Szabo, Moh'd A. Salameh, Maren Ludwig, Evette S. Radisky, and Miklos Sahin-TothFrom:PLoS ONE (Vol. 9, Issue 7) Peer-Reviewed

  July 10, 20145,523 words Article 1490LHuman cationic and anionic trypsins are sulfated on Tyr154, a residue which helps to shape the prime side substrate-binding subsites. Here, we used phage display technology to assess the significance of tyrosine...

• Association of the Brazil nut protein gene and kunitz trypsin inhibitor alleles with soybean protease inhibitor activity and agronomic traits

  Authors:Leon G. Streit, Larry R. Beach, James C. Register, III, Rudolph Jung, and Walter R. FehrFrom:Crop Science (Vol. 41, Issue 6) Peer-Reviewed

  November-December 20013,022 words Article The use of soybean [Glycine max (L.) Merr.] in animal feed without heat treatment may be possible by reducing protease inhibitors. The objectives of this study were to determine to what extent soybean protease...

• Trypsin-Like Serine Proteases in Lutzomyia longipalpis - Expression, Activity and Possible Modulation by Leishmania infantum chagasi

  Authors:Erich Loza Telleria, Adriana Pereira Oliveira de Araujo, Nagila Francinete Secundino, Claudia Masini d'Avila-Levy, and Yara Maria Traub-CsekoFrom:PLoS ONE (Vol. 5, Issue 5) Peer-Reviewed

  May 18, 20105,424 words Article 1460LBackground Midgut enzymatic activity is one of the obstacles that Leishmania must surpass to succeed in establishing infection. Trypsins are abundant digestive enzymes in most insects. We have previously described...

• Preparation and Antimicrobial Action of Three Tryptic Digested Functional Molecules of Bovine Lactoferrin

  Authors:Nilisha Rastogi, Nitish Nagpal, Hammad Alam, Sadanand Pandey, Lovely Gautam, Mau Sinha, et al.From:PLoS ONE (Vol. 9, Issue 3) Peer-Reviewed

  Mar. 3, 20146,744 words Article 1500LAuthor(s): Nilisha Rastogi 1, Nitish Nagpal 2, Hammad Alam 3, Sadanand Pandey 1, Lovely Gautam 1, Mau Sinha 1, Kouichirou Shin 4, Nikhat Manzoor 3, Jugsharan S. Virdi 2, Punit Kaur 1, Sujata Sharma 1,*, Tej P. Singh 1,*...

• Biochemical Characterization of Anopheles gambiae SRPN6, a Malaria Parasite Invasion Marker in Mosquitoes

  Authors:Chunju An, Yasuaki Hiromasa, Xin Zhang, Scott Lovell, Michal Zolkiewski, John M. Tomich, et al.From:PLoS ONE (Vol. 7, Issue 11) Peer-Reviewed

  Nov. 9, 20127,318 words Article 1470LAuthor(s): Chunju An 1 , 2 , Yasuaki Hiromasa 3 , Xin Zhang 1 , Scott Lovell 4 , Michal Zolkiewski 3 , John M. Tomich 3 , Kristin Michel 1 , * Introduction The concept that mosquito immunity could be an important...

• Second Blood Meal by Female Lutzomyia longipalpis: Enhancement by Oviposition and Its Effects on Digestion, Longevity, and Leishmania Infection.

  Authors:C.S. Moraes, K. Aguiar-Martins, S.G. Costa, P.A. Bates, R.J. Dillon, and F.A. GentaFrom:BioMed Research International (Vol. 2018) Peer-Reviewed

  Annual 20186,582 words Article 1450LLutzomyia longipalpis is the main vector of visceral leishmaniasis (VL) in America. Physiological and molecular mechanisms of Leishmania infection in sand flies have been studied during the first gonotrophic cycle. There...

• Expression Analysis of the Ligands for the Natural Killer Cell Receptors NKp30 and NKp44

  Authors:Andreina Byrd, Sabrina C. Hoffmann, Mostafa Jarahian, Frank Momburg, and Carsten WatzlFrom:PLoS ONE (Vol. 2, Issue 12) Peer-Reviewed

  Dec. 19, 20075,302 words Article 1400LBackground The natural cytotoxicity receptors (NCR) are important to stimulate the activity of Natural Killer (NK) cells against transformed cells. Identification of NCR ligands and their level of expression on...

• Alpha-COPI Coatomer Protein Is Required for Rough Endoplasmic Reticulum Whorl Formation in Mosquito Midgut Epithelial Cells

  Authors:Guoli Zhou, Jun Isoe, W. Antony Day, and Roger L. MiesfeldFrom:PLoS ONE (Vol. 6, Issue 3) Peer-Reviewed

  Mar. 31, 20117,519 words Article 1720LBackground One of the early events in midgut epithelial cells of Aedes aegypti mosquitoes is the dynamic reorganization of rough endoplasmic reticulum (RER) whorl structures coincident with the onset of blood meal...

• An Aedes aegypti-associated fungus increases susceptibility to dengue virus by modulating gut trypsin activity

  Authors:Yesseinia I Anglero-Rodriguez, Octavio AC Talyuli, Benjamin J Blumberg, Seokyoung Kang, Celia Demby, Alicia Shields, et al.From:eLife (Vol. 6) Peer-Reviewed

  Dec. 5, 201711,793 words Article 1350LTransmission of dengue virus (DENV) requires successful completion of the infection cycle in the Aedes aegypti vector, which is initiated in the midgut tissue after ingestion of an infectious blood meal. While certain...