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Academic Journals
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From:PLoS ONE (Vol. 11, Issue 4) Peer-ReviewedDevelopment of an effective vaccine against drug-resistant Mycobacterium tuberculosis (Mtb) is crucial for saving millions of premature deaths every year due to tuberculosis. This paper describes a web portal developed...
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From:PLoS ONE (Vol. 13, Issue 9) Peer-ReviewedTuberculin skin test (TST) is used most widely for the detection of latent tuberculosis infection (LTBI), even though evidences suggest that it could be underreporting the prevalence of LTBI particularly in high...
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From:BioMed Research InternationalPeer-ReviewedTwo lines of transgenic carrot plants producing Mycobacterium tuberculosis proteins (ESAT6 and CFP10) have been constructed. The target proteins are present in carrot storage roots at a level not less than 0.056% of the...
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From:Expert Review of Vaccines (Vol. 8, Issue 12) Peer-ReviewedAuthor(s): David N McMurray [[dagger]] 1 , Lan H Ly 2 Traditional roadblocks to effective TB control (e.g., lack of attention to the disease, lack of resources, antiquated diagnostic tests, lack of patient compliance...
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From:PLoS ONE (Vol. 10, Issue 10) Peer-ReviewedMycobacterium bovis bacillus Calmette-Guerin (BCG), the only licensed vaccine, shows limited protection efficacy against pulmonary tuberculosis (TB), particularly hypervirulent Mycobacterium tuberculosis (Mtb) strains,...
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From:Expert Review of Vaccines (Vol. 11, Issue 10) Peer-ReviewedAuthor(s): Neha Dalmia 1 , Alistair J Ramsay [*] 1 Keywords : BCG; lung immunity; mucosal delivery; prime-boost; recombinant viral vectors; systems biology; tuberculosis; T cell; vaccine TB is a global...
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From:Expert Review of Molecular Diagnostics (Vol. 2, Issue 2) Peer-ReviewedThe resurgence of tuberculosis worldwide has been accompanied by an increase in the incidence of multidrug-resistant tuberculosis on all continents. While significant advances have been made in the rapid and accurate...
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From:The Western Journal of Medicine (Vol. 163, Issue 5) Peer-ReviewedTo determine the proportion and distribution of drug-resistant Mycobacterium tuberculosis in California, we surveyed all California counties for drug-susceptibility test results for initial isolates from tuberculosis...
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From:PLoS ONE (Vol. 7, Issue 9) Peer-ReviewedAuthor(s): Van Anh Thi Nguyen 1 , * , Marc Choisy 2 , Duy Hung Nguyen 3 , Thanh Hoa Thi Tran 1 , Kim Lien Thi Pham 1 , Phuong Thao Thi Dinh 1 , Jules Philippe 1 , Thai Son Nguyen 4 , Minh Ly Ho 1 , Sang Van Tran 5 ,...
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From:Consultant (Vol. 37, Issue 3) Peer-ReviewedTuberculosis caused by Mycobacterium tuberculosis bacteria have emerged as one of the serious problems in the world. Screening, testing, and treatment of this disease were presented. The technique and importance of...
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From:Emerging Infectious Diseases (Vol. 26, Issue 3) Peer-ReviewedPathogen-based factors associated with tuberculosis (TB) in eastern Sudan are not well defined. We investigated genetic diversity, drug resistance, and possible transmission clusters of Mycobacterium tuberculosis...
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From:The Brazilian Journal of Infectious Diseases (Vol. 13, Issue 1) Peer-ReviewedWe evaluated the performance of the ELISA technique in the detection of IgA antibodies against different Mycobacterium tuberculosis antigenic preparations in serum samples from 49 patients with pulmonary tuberculosis...
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From:BioMed Research InternationalPeer-ReviewedTuberculosis (TB) remains a major health problem in Iraq but the strains responsible for the epidemic have been poorly characterized. Our aim was to characterize the TB strains circulating in Bagdad (Iraq). A total of...
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From:PLoS ONE (Vol. 12, Issue 7) Peer-ReviewedBackground/Aims Animal tuberculosis (TB) is a complex animal health problem that causes disruption to trade and significant economic losses. TB involves a multi-host system where sheep, traditionally considered a...
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From:PLoS ONE (Vol. 14, Issue 5) Peer-ReviewedThe NIAID TB Portals Program (TBPP) established a unique and growing database repository of socioeconomic, geographic, clinical, laboratory, radiological, and genomic data from patient cases of drug-resistant...
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From:Science (Vol. 289, Issue 5482) Peer-ReviewedEasily the most successful human pathogen in the world, the bacterium that causes tuberculosis infects one-third of the world's population. Often acting in deadly combination with AIDS, TB kills 2 million to 3 million...
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From:BMC Research Notes (Vol. 5) Peer-ReviewedBackground Capilia TB is a simple immunochromatographic assay based on the detection of MPB64 antigen specifically secreted by the Mycobacterium tuberculosis complex (MTC). Capilia TB was evaluated for rapid...
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From:Journal of Clinical Investigation (Vol. 130, Issue 1) Peer-ReviewedUnconventional T cells that recognize mycobacterial antigens are of great interest as potential vaccine targets against tuberculosis (TB). This includes donor-unrestricted T cells (DURTs), such as mucosa-associated...
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From:PLoS ONE (Vol. 11, Issue 2) Peer-ReviewedMycobacterium tuberculosis is an extremely successful intracellular pathogen that has evolved a broad spectrum of pathogenic mechanisms that enable its manipulation of host defense elements and its survival in the...
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From:PLoS ONE (Vol. 9, Issue 2) Peer-ReviewedAuthor(s): Kenji Toyonaga 1, Yasunobu Miyake 1,2,*, Sho Yamasaki 1,2,* Introduction Tuberculosis is a life-threatening disease caused by the infection of Mycobacterium tuberculosis (M. tuberculosis ) and related...