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• Vascular endothelial growth factor expression and angiogenesis in various grades and subtypes of meningioma

  Authors:Priya Dharmalingam, V. Roopesh Kumar, and Surendra VermaFrom:Indian Journal of Pathology and Microbiology (Vol. 56, Issue 4) Peer-Reviewed

  October-December 20133,857 words Report 1550LByline: Priya. Dharmalingam, V. Roopesh Kumar, Surendra. Verma Background: Vascular endothelial growth factor (VEGF) expression has been extensively studied in astrocytoma, whereas relatively less literature exists...

• Targeting mTOR pathway: A new concept in cancer therapy

  Author:S. AdvaniFrom:Indian Journal of Medical and Paediatric Oncology (Vol. 31, Issue 4) Peer-Reviewed

  October-December 20103,461 words Report 2210LByline: S. Advani This article highlights the current knowledge of mTOR biology and provides new insights into the role of mTOR in different cancers. An active mTOR coordinates a response in cell growth directly...

• Vascular endothelial growth factor: a new frontier in macular degeneration; A look at the most promising treatments for patients with AMD

  Author:Jeffry GersonFrom:Review of Optometry (Vol. 143, Issue 11) Peer-Reviewed

  Nov. 15, 20062,881 words Article 1700LAge-related macular degeneration (AMD) is the leading cause of severe vision loss in the Western world. (1) In the United States alone, advanced AMD affects more than 1 million people, and approximately 8 million more...

• Evidence for systemic endothelial dysfunction in patients and first-order relatives with pulmonary arterial hypertension

  Authors:R. Hughes, J. Tong, C. Oates, J. Lordan, and P.A. CorrisFrom:Chest (Vol. 128, Issue 6) Peer-Reviewed

  Dec. 2005335 words Brief article Abbreviations: GTN = glyceryl trinitrate; NO = nitric oxide; PAH = pulmonary arterial hypertension Dysfunction of pulmonary endothelial cells plays an important role in the pathogenesis of pulmonary arterial...

• Anti-VEGF patterns of use may vary for DME cases in clinical practice: injections are less frequent and treatment is less effective than in registration trials

  Author:Laird HarrisonFrom:Ophthalmology Times (Vol. 40, Issue 15) Peer-Reviewed

  Sept. 15, 2015620 words Article 1280LST. LOUIS, MO :: ANTI-VASCULAR ENDOTHELIAL growth factor (VEGF) treatments for diabetic macular edema (DME) have not worked as well in clinical practice as in clinical trials, according to one clinician....

• Improving treatment of liver metastases by targeting nonangiogenic mechanisms

  Authors:Kyrre E Emblem and Rakesh K JainFrom:Nature Medicine (Vol. 22, Issue 11) Peer-Reviewed

  Nov. 20161,499 words Report 1570LAuthor(s): Kyrre E Emblem (corresponding author) [1]; Rakesh K Jain [2] Since 2004, a dozen drugs that target either VEGFA or its receptors have been approved for the treatment of ten different malignancies. In...

• Insufficient Radiofrequency Ablation Promotes Angiogenesis of Residual Hepatocellular Carcinoma via HIF-1[alpha]/VEGFA

  Authors:Jian Kong, Jinge Kong, Bing Pan, Shan Ke, Shuying Dong, Xiuli Li, et al.From:PLoS ONE (Vol. 7, Issue 5) Peer-Reviewed

  May 15, 20126,668 words Article 1400LAuthor(s): Jian Kong 1 , Jinge Kong 2 , Bing Pan 2 , Shan Ke 1 , Shuying Dong 1 , Xiuli Li 3 , Aimin Zhou 4 , Lemin Zheng 2 , * , Wen-bing Sun 1 , * Introduction Hepatocellular carcinoma (HCC) is the fifth most...

• Epidermal Expression of Neuropilin 1 Protects Murine keratinocytes from UVB-induced apoptosis

  Authors:Anna Riese, Yvonne Eilert, Yvonne Meyer, Meral Arin, Jens M. Baron, Sabine Eming, et al.From:PLoS ONE (Vol. 7, Issue 12) Peer-Reviewed

  Dec. 10, 20126,246 words Article 1420LAuthor(s): Anna Riese 1 , Yvonne Eilert 1 , Yvonne Meyer 1 , Meral Arin 1 , Jens M. Baron 2 , Sabine Eming 1 , Thomas Krieg 1 , Peter Kurschat 1 , * Introduction Like no other organ the human skin as the outer...

• Platelet Activation Determines Angiopoietin-1 and VEGF Levels in Malaria: Implications for Their Use as Biomarkers

  Authors:Judith Brouwers, Rintis Noviyanti, Rob Fijnheer, Philip G. de Groot, Leily Trianty, Siti Mudaliana, et al.From:PLoS ONE (Vol. 8, Issue 6) Peer-Reviewed

  June 3, 20133,562 words Report 1470LAuthor(s): Judith Brouwers 1, Rintis Noviyanti 2, Rob Fijnheer 1, Philip G. de Groot 1, Leily Trianty 2, Siti Mudaliana 2, Mark Roest 1, Din Syafruddin 2, Andre van der Ven 3, Quirijn de Mast 1,3,* Introduction...

• HIF-1[alpha] and HIF-2[alpha]: Siblings in Promoting Angiogenesis of Residual Hepatocellular Carcinoma after High-Intensity Focused Ultrasound Ablation

  Authors:Lun Wu, Zhihao Fu, Shiji Zhou, Jianping Gong, Chang An Liu, Zhengrong Qiao, et al.From:PLoS ONE (Vol. 9, Issue 2) Peer-Reviewed

  Feb. 13, 20145,683 words Article 1400LAuthor(s): Lun Wu 1, Zhihao Fu 1, Shiji Zhou 2, Jianping Gong 1, Chang An Liu 1, Zhengrong Qiao 3, Shengwei Li 1,* Introduction Hepatocellular carcinoma (HCC) is the sixth most common cancer, and the third most...

• Preconditioning of Mesenchymal Stem Cells by Sevoflurane to Improve Their Therapeutic Potential

  Authors:Xuejun Sun, Bo Fang, Xi Zhao, Guangwei Zhang, and Hong MaFrom:PLoS ONE (Vol. 9, Issue 3) Peer-Reviewed

  Mar. 5, 20144,368 words Article 1320LAuthor(s): Xuejun Sun 1, Bo Fang 1, Xi Zhao 1, Guangwei Zhang 2, Hong Ma 1,* Introduction Bone marrow mesenchymal stem cells (MSCs) transplantation is an attractive therapeutic method for tissue injuries, such as...

• Silencing Alpha-Fetoprotein Inhibits VEGF and MMP-2/9 Production in Human Hepatocellular Carcinoma Cell

  Authors:Wenbo Meng, Xun Li, Zhongtian Bai, Yan Li, Jinqiu Yuan, Tao Liu, et al.From:PLoS ONE (Vol. 9, Issue 2) Peer-Reviewed

  Feb. 28, 20144,112 words Article 1490LAuthor(s): Wenbo Meng 1,2, Xun Li 3,*, Zhongtian Bai 3, Yan Li 4, Jinqiu Yuan 5, Tao Liu 1, Jun Yan 3, Wence Zhou 3, Kexiang Zhu 3, Hui Zhang 3, Yumin Li 1,* Introduction Human hepatocellular carcinoma (HCC) is...

• Distinct Phenotypic Differences Associated with Differential Amplification of Receptor Tyrosine Kinase Genes at 4q12 in Glioblastoma

  Authors:Anna Burford, Suzanne E. Little, Alexa Jury, Sergey Popov, Ross Laxton, Lawrence Doey, et al.From:PLoS ONE (Vol. 8, Issue 8) Peer-Reviewed

  Aug. 21, 20135,151 words Article 1530LAuthor(s): Anna Burford 1,2, Suzanne E. Little 1,2, Alexa Jury 1,2, Sergey Popov 1,2, Ross Laxton 3, Lawrence Doey 3, Safa Al-Sarraj 3, Juliane M. Jürgensmeier 4, Chris Jones 1,2,* Introduction Molecular profiling...

• Hypoxia Promotes Osteogenesis but Suppresses Adipogenesis of Human Mesenchymal Stromal Cells in a Hypoxia-Inducible Factor-1 Dependent Manner

  Authors:Markus Wagegg, Timo Gaber, Ferenz L. Lohanatha, Martin Hahne, Cindy Strehl, Monique Fangradt, et al.From:PLoS ONE (Vol. 7, Issue 9) Peer-Reviewed

  Sept. 27, 20125,810 words Report 1570LAuthor(s): Markus Wagegg 1 , 2 , 3 , Timo Gaber 1 , 2 , 3 , * , Ferenz L. Lohanatha 1 , 2 , 3 , Martin Hahne 1 , 2 , 6 , Cindy Strehl 1 , 2 , Monique Fangradt 1 , 2 , Cam Loan Tran 1 , 2 , Kerstin Schönbeck 1 , 2 ,...

• Treating ROP: Anti-VEGF or laser: Anti-VEGF. Benefits substantial, while recurrence a risk

  Author:Cheryl Guttman KraderFrom:Ophthalmology Times (Vol. 42, Issue 9) Peer-Reviewed

  June 1, 2017597 words Report 1550LANTI-VEGF THERAPY for Zone I retinopathy of prematurity (ROP) is associated with better structural and functional outcomes than laser therapy, but also a longer recurrence risk period, said Helen A. Mintz-Hittner, MD....

• Refined Mapping of a Quantitative Trait Locus on Chromosome 1 Responsible for Mouse Embryonic Death

  Authors:Magalie Vatin, Gaetan Burgio, Gilles Renault, Paul Laissue, Virginie Firlej, Francoise Mondon, et al.From:PLoS ONE (Vol. 7, Issue 8) Peer-Reviewed

  Aug. 16, 20126,953 words Article 1490LAuthor(s): Magalie Vatin 1 , Gaetan Burgio 2 , 3 , Gilles Renault 1 , Paul Laissue 4 , Virginie Firlej 1 , Françoise Mondon 1 , Xavier Montagutelli 2 , Daniel Vaiman 1 , Catherine Serres 1 , Ahmed Ziyyat 1 , *...

• Diagnostic Value of Vascular Endothelial Growth Factor, Transforming Growth Factor-[beta], Interleukin-8, and the Ratio of Lactate Dehydrogenase to Adenosine Deaminase in Pleural Effusion

  Authors:Takeshi Saraya, Kosuke Ohkuma, Takayasu Watanabe, Sunao Mikura, Fumi Kobayashi, Junpei Aso, et al.From:Lung (Vol. 196, Issue 2) Peer-Reviewed

  Apr. 20183,012 words Report 1480LAuthor(s): Takeshi Saraya 1 , Kosuke Ohkuma 1 , Takayasu Watanabe 1 , Sunao Mikura 1 , Fumi Kobayashi 1 , Junpei Aso 1 , Hiroki Nunokawa 1 , Kojiro Honda 1 , Yukari Ogawa 1 , Masaki Tamura 1 , Mitsuru Sada 1 , Miku Oda...

• Two-Year Outcome of Aflibercept in Patients with Pigment Epithelial Detachment due to Neovascular Age-Related Macular Degeneration (nAMD) Refractory to Ranibizumab

  Authors:Thi Ha Chau Tran, Stephane Dumas, and Florence CoscasFrom:Journal of Ophthalmology (Vol. 2017) Peer-Reviewed

  Annual 20175,347 words Article 1500LPurpose. To evaluate the response of intravitreal aflibercept injection (IAI) in eyes with detachment of retinal pigment epithelium (DEP) secondary to nAMD refractory to monthly ranibizumab. Patients and Methods. This...

• Loss of HIF-2[alpha] and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

  Authors:Veerle Compernolle, Koen Brusselmans, Till Acker, Peter Hoet, Marc Tjwa, Heike Beck, et al.From:Nature Medicine (Vol. 8, Issue 7) Peer-Reviewed

  July 20026,098 words Article 1470LRespiratory distress syndrome (RDS) due to insufficient production of surfactant is a common and severe complication of preterm delivery. Here, we report that loss of the hypoxia-inducible transcription factor-2[alpha]...

• Dihydropyrimidinase-like 3 facilitates malignant behavior of gastric cancer

  Authors:Mitsuro Kanda, Shuji Nomoto, Hisaharu Oya, Dai Shimizu, Hideki Takami, Soki Hibino, et al.From:Journal of Experimental & Clinical Cancer Research (Vol. 33, Issue 1) Peer-Reviewed

  Aug. 6, 20143,938 words Article 1450LAuthor(s): Mitsuro Kanda1 , Shuji Nomoto1 , Hisaharu Oya1 , Dai Shimizu1 , Hideki Takami1 , Soki Hibino1 , Ryoji Hashimoto1 , Daisuke Kobayashi1 , Chie Tanaka1 , Suguru Yamada1 , Tsutomu Fujii1 , Goro Nakayama1 ,...