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    Academic Journals

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• Select SRSF1 regulates primordial follicle formation and number determination during meiotic prophase I.

  1

  SRSF1 regulates primordial follicle formation and number determination during meiotic prophase I.

  Authors:Longjie Sun, Zheng Lv, Xuexue Chen, Chaofan Wang, Pengbo Lv, Lu Yan, et al.From:BMC Biology (Vol. 21, Issue 1) Peer-Reviewed

  Mar. 8, 20238,646 words Report 1380LBackground Ovarian folliculogenesis is a tightly regulated process leading to the formation of functional oocytes and involving successive quality control mechanisms that monitor chromosomal DNA integrity and meiotic...
• Select Differential requirement for BRCA1-BARD1 E3 ubiquitin ligase activity in DNA damage repair and meiosis in the Caenorhabditis elegans germ line.

  2

  Differential requirement for BRCA1-BARD1 E3 ubiquitin ligase activity in DNA damage repair and meiosis in the Caenorhabditis elegans germ line.

  Authors:Qianyan Li, Arshdeep Kaur, Kyoko Okada, Richard J. McKenney, and JoAnne EngebrechtFrom:PLoS Genetics (Vol. 19, Issue 1) Peer-Reviewed

  Jan. 30, 202314,407 words Report 1490LThe tumor suppressor BRCA1-BARD1 complex regulates many cellular processes; of critical importance to its tumor suppressor function is its role in genome integrity. Although RING E3 ubiquitin ligase activity is the only...
• Select Chromatin landscape, DSB levels, and cKU-70/80 contribute to patterning of meiotic DSB processing along chromosomes in C. elegans.

  3

  Chromatin landscape, DSB levels, and cKU-70/80 contribute to patterning of meiotic DSB processing along chromosomes in C. elegans.

  Authors:Laura I. Lascarez-Lagunas, Marina Martinez-Garcia, Saravanapriah Nadarajan, Brianna N. Diaz-Pacheco, Elizaveta Berson, and Mónica P. ColaiácovoFrom:PLoS Genetics (Vol. 19, Issue 1) Peer-Reviewed

  Jan. 27, 202313,875 words Report 1550LProgrammed DNA double-strand break (DSB) formation is essential for achieving accurate chromosome segregation during meiosis. DSB repair timing and template choice are tightly regulated. However, little is known about...
• Select C. elegans XMAP215/ZYG-9 and TACC/TAC-1 act at multiple times during oocyte meiotic spindle assembly and promote both spindle pole coalescence and stability.

  4

  C. elegans XMAP215/ZYG-9 and TACC/TAC-1 act at multiple times during oocyte meiotic spindle assembly and promote both spindle pole coalescence and stability.

  Authors:Austin M. Harvey, Chien-Hui Chuang, Eisuke Sumiyoshi, and Bruce BowermanFrom:PLoS Genetics (Vol. 19, Issue 1) Peer-Reviewed

  Jan. 6, 202318,027 words Report 1690LThe conserved two-component XMAP215/TACC modulator of microtubule stability is required in multiple animal phyla for acentrosomal spindle assembly during oocyte meiotic cell division. In C. elegans, XMAP215/zyg-9 and...
• Select Lessons from the meiotic recombination landscape of the ZMM deficient budding yeast Lachancea waltii.

  5

  Lessons from the meiotic recombination landscape of the ZMM deficient budding yeast Lachancea waltii.

  Authors:Fabien Dutreux, Abhishek Dutta, Emilien Peltier, Sabrina Bibi-Triki, Anne Friedrich, Bertrand Llorente, et al.From:PLoS Genetics (Vol. 19, Issue 1) Peer-Reviewed

  Jan. 6, 202312,450 words Report 1460LMeiotic recombination is a driving force for genome evolution, deeply characterized in a few model species, notably in the budding yeast Saccharomyces cerevisiae. Interestingly, Zip2, Zip3, Zip4, Spo16, Msh4, and Msh5,...
• Select Occurrence of late-apoptotic symptoms in porcine preimplantation embryos upon exposure of oocytes to perfluoroalkyl substances (PFASs) under in vitro meiotic maturation.

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  Occurrence of late-apoptotic symptoms in porcine preimplantation embryos upon exposure of oocytes to perfluoroalkyl substances (PFASs) under in vitro meiotic maturation.

  Authors:Anna Leclercq, Petter Ranefall, Ylva Cecilia Björnsdotter Sjunnesson, and Ida HallbergFrom:PLoS ONE (Vol. 17, Issue 12) Peer-Reviewed

  Dec. 28, 20227,039 words Report 1390LThe objectives of this study were to evaluate the effect of perfluoroalkyl substances on early embryonic development and apoptosis in blastocysts using a porcine in vitro model. Porcine oocytes (N = 855) collected from...
• Select Rad51-mediated interhomolog recombination during budding yeast meiosis is promoted by the meiotic recombination checkpoint and the conserved Pif1 helicase.

  7

  Rad51-mediated interhomolog recombination during budding yeast meiosis is promoted by the meiotic recombination checkpoint and the conserved Pif1 helicase.

  Authors:Andrew Ziesel, Qixuan Weng, Jasvinder S. Ahuja, Abhishek Bhattacharya, Raunak Dutta, Evan Cheng, et al.From:PLoS Genetics (Vol. 18, Issue 12) Peer-Reviewed

  Dec. 12, 202223,615 words Report 1470LDuring meiosis, recombination between homologous chromosomes (homologs) generates crossovers that promote proper segregation at the first meiotic division. Recombination is initiated by Spo11-catalyzed DNA double strand...
• Select Homologous chromosomes are stably conjoined for Drosophila male meiosis I by SUM, a multimerized protein assembly with modules for DNA-binding and for separase-mediated dissociation co-opted from cohesin.

  8

  Homologous chromosomes are stably conjoined for Drosophila male meiosis I by SUM, a multimerized protein assembly with modules for DNA-binding and for separase-mediated dissociation co-opted from cohesin.

  Authors:Zeynep Kabakci, Heidi E. Reichle, Bianca Lemke, Dorota Rousova, Samir Gupta, Joe Weber, et al.From:PLoS Genetics (Vol. 18, Issue 12) Peer-Reviewed

  Dec. 8, 202220,880 words Report 1490LFor meiosis I, homologous chromosomes must be paired into bivalents. Maintenance of homolog conjunction in bivalents until anaphase I depends on crossovers in canonical meiosis. However, instead of crossovers, an...
• Select S. pombe wtf drivers use dual transcriptional regulation and selective protein exclusion from spores to cause meiotic drive.

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  S. pombe wtf drivers use dual transcriptional regulation and selective protein exclusion from spores to cause meiotic drive.

  Authors:Nicole L. Nuckolls, Ananya Nidamangala Srinivasa, Anthony C. Mok, Rachel M. Helston, María Angélica Bravo Núñez, Jeffrey J. Lange, et al.From:PLoS Genetics (Vol. 18, Issue 12) Peer-Reviewed

  Dec. 7, 202218,116 words Report 1410LMeiotic drivers bias gametogenesis to ensure their transmission into more than half the offspring of a heterozygote. In Schizosaccharomyces pombe, wtf meiotic drivers destroy the meiotic products (spores) that do not...
• Select ZYG-9.sup.ch-TOG promotes the stability of acentrosomal poles via regulation of spindle microtubules in C. elegans oocyte meiosis.

  10

  ZYG-9.sup.ch-TOG promotes the stability of acentrosomal poles via regulation of spindle microtubules in C. elegans oocyte meiosis.

  Authors:Gabriel Cavin-Meza, Timothy J. Mullen, Emily R. Czajkowski, Ian D. Wolff, Nikita S. Divekar, Justin D. Finkle, et al.From:PLoS Genetics (Vol. 18, Issue 11) Peer-Reviewed

  Nov. 30, 202215,292 words Report 1440LDuring mitosis, centrosomes serve as microtubule organizing centers that guide the formation of a bipolar spindle. However, oocytes of many species lack centrosomes; how meiotic spindles establish and maintain these...
• Select Studies from University of Connecticut Reveal New Findings on Life Science (Active Meiosis During Dinoflagellate Blooms: a 'sex for Proliferation' Hypothesis).

  11

  Studies from University of Connecticut Reveal New Findings on Life Science (Active Meiosis During Dinoflagellate Blooms: a 'sex for Proliferation' Hypothesis).

  From:Obesity, Fitness & Wellness Week

  Nov. 5, 2022536 words Article 1510L2022 NOV 5 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New research on Life Science is the subject of a report. According to news reporting originating from Groton,...
• Select Teflon promotes chromosomal recruitment of homolog conjunction proteins during Drosophila male meiosis.

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  Teflon promotes chromosomal recruitment of homolog conjunction proteins during Drosophila male meiosis.

  Authors:Zeynep Kabakci, Hiro Yamada, Luisa Vernizzi, Samir Gupta, Joe Weber, Michael Shoujie Sun, et al.From:PLoS Genetics (Vol. 18, Issue 10) Peer-Reviewed

  Oct. 17, 202222,884 words Report 1470LMeiosis in males of higher dipterans is achiasmate. In their spermatocytes, pairing of homologs into bivalent chromosomes does not include synaptonemal complex and crossover formation. While crossovers preserve homolog...
• Select Comparison of meiotic transcriptomes of three maize inbreds with different origins reveals differences in cell cycle and recombination.

  13

  Comparison of meiotic transcriptomes of three maize inbreds with different origins reveals differences in cell cycle and recombination.

  Authors:Nelson Garcia, Lu Yin, Stefanie Dukowic-Schulze, Claire Milsted, Penny M. A. Kianian, Shahryar Kianian, et al.From:BMC Genomics (Vol. 23, Issue 1) Peer-Reviewed

  Oct. 12, 20227,645 words Report 1530LBackground Cellular events during meiosis can differ between inbred lines in maize. Substantial differences in the average numbers of chiasmata and double-strand breaks (DSBs) per meiotic cell have been documented...
• Select Delivery of ceramide phosphoethanolamine lipids to the cleavage furrow through the endocytic pathway is essential for male meiotic cytokinesis.

  14

  Delivery of ceramide phosphoethanolamine lipids to the cleavage furrow through the endocytic pathway is essential for male meiotic cytokinesis.

  Authors:Govind Kunduri, Si-Hung Le, Valentina Baena, Nagampalli Vijaykrishna, Adam Harned, Kunio Nagashima, et al.From:PLoS Biology (Vol. 20, Issue 9) Peer-Reviewed

  Sept. 28, 202222,500 words Report 1470LCell division, wherein 1 cell divides into 2 daughter cells, is fundamental to all living organisms. Cytokinesis, the final step in cell division, begins with the formation of an actomyosin contractile ring, positioned...
• Select Diversity and determinants of recombination landscapes in flowering plants.

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  Diversity and determinants of recombination landscapes in flowering plants.

  Authors:Thomas Brazier and Sylvain GléminFrom:PLoS Genetics (Vol. 18, Issue 8) Peer-Reviewed

  Aug. 30, 202214,035 words Report 1510LDuring meiosis, crossover rates are not randomly distributed along the chromosome and their location may have a strong impact on the functioning and evolution of the genome. To date, the broad diversity of recombination...
• Select DMC1 attenuates RAD51-mediated recombination in Arabidopsis.

  16

  DMC1 attenuates RAD51-mediated recombination in Arabidopsis.

  Authors:Olivier Da Ines, Jeanne Bazile, Maria E. Gallego, and Charles I. WhiteFrom:PLoS Genetics (Vol. 18, Issue 8) Peer-Reviewed

  Aug. 25, 202214,619 words Report 1450LEnsuring balanced distribution of chromosomes in gametes, meiotic recombination is essential for fertility in most sexually reproducing organisms. The repair of the programmed DNA double strand breaks that initiate...
• Select Differentiated function and localisation of SPO11-1 and PRD3 on the chromosome axis during meiotic DSB formation in Arabidopsis thaliana.

  17

  Differentiated function and localisation of SPO11-1 and PRD3 on the chromosome axis during meiotic DSB formation in Arabidopsis thaliana.

  Authors:Christophe Lambing, Pallas Kuo, Jaeil Kim, Kim Osman, Amy Leanne Whitbread, Jianhua Yang, et al.From:PLoS Genetics (Vol. 18, Issue 7) Peer-Reviewed

  July 20, 202212,555 words Report 1460LDuring meiosis, DNA double-strand breaks (DSBs) occur throughout the genome, a subset of which are repaired to form reciprocal crossovers between chromosomes. Crossovers are essential to ensure balanced chromosome...
• Select Multi-color dSTORM microscopy in Hormad1.sup.-/.sup.- spermatocytes reveals alterations in meiotic recombination intermediates and synaptonemal complex structure.

  18

  Multi-color dSTORM microscopy in Hormad1.sup.-/.sup.- spermatocytes reveals alterations in meiotic recombination intermediates and synaptonemal complex structure.

  Authors:Lieke Koornneef, Johan A. Slotman, Esther Sleddens-Linkels, Wiggert A. van Cappellen, Marco Barchi, Attila Tóth, et al.From:PLoS Genetics (Vol. 18, Issue 7) Peer-Reviewed

  July 20, 202217,277 words Report 1480LRecombinases RAD51 and its meiosis-specific paralog DMC1 accumulate on single-stranded DNA (ssDNA) of programmed DNA double strand breaks (DSBs) in meiosis. Here we used three-color dSTORM microscopy, and a mouse model...
• Select The meiotic cohesin subunit REC8 contributes to multigenic adaptive evolution of autopolyploid meiosis in Arabidopsis arenosa.

  19

  The meiotic cohesin subunit REC8 contributes to multigenic adaptive evolution of autopolyploid meiosis in Arabidopsis arenosa.

  Authors:Chris Morgan, Emilie Knight, and Kirsten BombliesFrom:PLoS Genetics (Vol. 18, Issue 7) Peer-Reviewed

  July 13, 202210,517 words Report 1660LGenome duplication, which leads to polyploidy, poses challenges to the meiotic segregation of the now-multiple homologous chromosome copies. Genome scan data showed previously that adaptation to polyploid meiosis in...
• Select Novel copy number variations within SYCE1 caused meiotic arrest and non-obstructive azoospermia.

  20

  Novel copy number variations within SYCE1 caused meiotic arrest and non-obstructive azoospermia.

  Authors:Yuhua Huang, Ruhui Tian, Junwei Xu, Zhiyong Ji, Yuxiang Zhang, Liangyu Zhao, et al.From:BMC Medical Genomics (Vol. 15, Issue 1) Peer-Reviewed

  June 19, 20224,487 words Report 1310LBackground Non-obstructive azoospermia (NOA) is the most severe disease in male infertility, but the genetic causes for majority of NOA remain unknown. Methods Two Chinese NOA-affected patients were recruited to...