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    Academic Journals

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• Small Round Cell Tumors of Soft Tissue and Bone.

  Authors:Shi Wei and Gene P. SiegalFrom:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20228,092 words Report 1660L* Context.--Small round cell tumors of soft tissue and bone constitute a divergent group of neoplasms. These lesions often demonstrate overlapping clinical and radiologic characteristics and share histomorphologic and...

• Laboratory and Clinical Implications of Incidental and Secondary Germline Findings During Tumor Testing.

  Authors:Allison Cushman-Vokoun, Josh Lauring, John Pfeifer, Damon R. Olson, Anna Berry, John Thorson, et al.From:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20226,737 words Report 1750L* Context.--Next-generation sequencing is a powerful clinical tool for cancer management but can produce incidental/secondary findings that require special consideration. Objective.--To discuss clinical and laboratory...

• Establishing a Professionalism and Communication Curriculum at the University of Mississippi Medical Center Department of Pathology.

  Authors:Timothy Craig Allen and Patrick O. SmithFrom:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20222,512 words Editorial 1920L"I spoke with the residency director of Pathology. We both agree you'll be a great fit there ... Given your difficulties with communication and social cues I think it will be a much better fit." --The Good Doctor (1)...

• Evaluation of Exome Sequencing Criteria for Hospital Stewardship and Insurance Authorization at a Pediatric Hospital.

  Authors:Claire L. Wittowski, Sarah Clowes Candadai, Marie E. Perrone, Daniel F. Gallego, Jessie H. Conta, and Jane A. DickersonFrom:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20223,989 words Report 1560L* Context.--Genomic molecular testing practices in a pediatric tertiary care institution can vary in utility by patient indication. Objective.--To evaluate exome sequencing (ES) ordering practices and the effects of...

• One-Step Multiplexed Droplet Digital Polymerase Chain Reaction for Quantification of p190 BCR-ABL1 Fusion Transcript in B-Lymphoblastic Leukemia.

  Authors:Ryan J. Martinez, Qing Kang, Davis Nennig, Nathanael G. Bailey, Noah A. Brown, Bryan L. Betz, et al.From:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20225,651 words Report 1600L* Context.--Quantification and detection of the t(9;22) (BCR-ABL1) translocation in chronic myelogenous leukemia and B-lymphoblastic leukemia are important for directing treatment protocols and monitoring disease...

• Pancreatic Frozen Section Guides Operative Management With Few Deferrals and Errors: Five-Year Experience at a Large Academic Institution.

  Authors:Jesus A. Chavez, Wei Chen, C. Eric Freitag, and Wendy L. FrankelFrom:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20225,796 words Report 1520L* Context.--Pancreatic adenocarcinoma is the third leading cause of cancer death in the United States. Surgery remains the mainstay of treatment, and frozen section analysis is used to confirm diagnosis and determine...

• Early Antibody Temporal Responses to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Vaccinated Subjects Determined by the cobas 6000 Spike Assay.

  Authors:Hanna S. Loving, Paulina Stallcup, Peter Burbelo, Jeffrey Cohen, Alan Remaley, David B. Sacks, et al.From:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20221,052 words Letter to the editor 1420LTo the Editor.--Three coronavirus disease 2019 (COVID-19) vaccines targeting the viral spike protein (S) (1) have received US Food and Drug Administration (FDA) Emergency Use Authorization (EUA). (2) We measured levels...

• Rosai-Dorfman Disease of Bone and Soft Tissue.

  Authors:Roberto A. Garcia and Edward F. DiCarloFrom:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20225,102 words Report 1990L* Context.--Rosai-Dorfman disease is a rare histiocytic proliferative disorder of unknown pathogenesis that may be diagnostically difficult in extranodal sites. It is commonly an unsuspected diagnosis when arising in...

• A Deep Learning Convolutional Neural Network Can Differentiate Between Helicobacter Pylori Gastritis and Autoimmune Gastritis With Results Comparable to Gastrointestinal Pathologists.

  Authors:Michael M. Franklin, Fred A. Schultz, Marissa A. Tafoya, Audra A. Kerwin, Cory J. Broehm, Edgar G. Fischer, et al.From:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20223,797 words Report 1590L* Context.--Pathology studies using convolutional neural networks (CNNs) have focused on neoplasms, while studies in inflammatory pathology are rare. We previously demonstrated a CNN that differentiates reactive...

• Risk Assessment of Hospitalized Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-Infected Patients Using Laboratory Data and Immune Cell Morphologic Assessment.

  Authors:Thane Kubik, Mary Hou, Tammie Traverse, Mireille Lareau, Veronika Jenei, Lisa Oberding, et al.From:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20224,618 words Report 1600L* Context.--The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly infectious agent, with the propensity to cause severe illness. While vaccine uptake has been increasing in recent months, many...

• Hot Seat Diagnosis: Competency-Based Tool Is Superior to Time-Based Tool for the Formative In-Service Assessment of Pathology Trainees.

  Authors:Rachel Han, Julia Keith, Elzbieta Slodkowska, Sharon Nofech-Mozes, Bojana Djordjevic, Carlos Parra-Herran, et al.From:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20225,819 words Report 1630L* Context.--Competency-based medical education relies on frequent formative in-service assessments to ascertain trainee progression. Currently at our institution, trainees receive a summative end-of-rotation In-Training...

• Elevated von Willebrand Factor Antigen Is an Early Predictor of Mortality and Prolonged Length of Stay for Coronavirus Disease 2019 (COVID-19) Inpatients.

  Authors:Alexander H. Cotter, Su-Jau T. Yang, Hedyeh Shafi, Timothy M. Cotter, and Darryl Erik Palmer-ToyFrom:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20222,302 words Report 1370L* Context.--Coagulation factor and endothelial injury marker, von Willebrand factor antigen (vWF:Ag), is elevated in coronavirus disease 2019 (COVID-19). Objective.--To assess the prognostic value of vWF:Ag for...

• Some Reactive Lesions of Bone Are Probably Neoplasms: A Review.

  Authors:Raima A. Memon, Shi Wei, and Gene P. SiegalFrom:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20226,207 words Report 1800L* Context.--A number of fibro-osseous and osteocartilaginous lesions, especially common in the small bones of the hand and feet, pose a diagnostic challenge and have historically been thought to be reactive lesions....

• Rescreening Practices of Negative Papanicolaou Tests With Positive Human Papillomavirus Test Result: Survey Results of Laboratories Participating in the College of American Pathologists Gynecologic Cytology (PAP Education) Program.

  Authors:Abha Goyal, Diane D. Davey, Rhona J. Souers, Sana O. Tabbara, Kelly Goodrich, and Christine N. BoothFrom:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20223,611 words Report 1670L* Context.--The yield of the prospective rescreening process for "negative for intraepithelial lesion or malignancy" (NILM) Papanicolaou (Pap) tests is higher with the inclusion of a greater proportion of high-risk...

• Undiagnosed Malignancy and Therapeutic Complications in Oncology Patients: A 10-Year Review of Autopsy Cases.

  Authors:Noman Javed, Justin Rueckert, and Sharon MountFrom:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20223,591 words Report 1530L* Context.--Despite technologic and medical advancements, autopsies are essential to uncover clinically unsuspected diagnoses, to advance our understanding of disease processes, and to help reduce medical errors....

• Frontiers in Bone, Soft Tissue, and Hematologic Pathology.

  Author:Lanjing ZhangFrom:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20221,030 words Report 1420LThis special section of 6 articles includes the proceedings of the Seventh Princeton Integrated Pathology Symposium (PIPS): Bone, Soft Tissue and Hematologic Pathology, and other related reviews. The symposium was held...

• Analyzing Anatomic Pathology On-Call Summaries to Improve Resident Education.

  Authors:Ying Liu, Danielle Payne-Uprichard, Dorina Gui, Morgan A. Darrow, Hooman H. Rashidi, and Karen MatsukumaFrom:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20222,794 words Report 1670L* Context.--Pathology on-call experiences help prepare trainees for successful transition from residency to independent practice, and as such are an integral component of training. However, few data exist on anatomic...

• Diagnostic Strategies for Endemic Coronavirus Disease 2019 (COVID-19): Rapid Antigen Tests, Repeated Testing, and Prevalence Boundaries.

  Author:Gerald J. KostFrom:Archives of Pathology & Laboratory Medicine (Vol. 146, Issue 1) Peer-Reviewed

  Jan. 20225,155 words Article 1640L* Context.--Coronavirus disease 2019 (COVID-19) rapid antigen tests generate intrinsically fast, inherently spatial, and immediately actionable results. They quickly confirm COVID-19, but weakly rule out infection. Test...