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    Academic Journals

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• Sophoridine Inhibits Breast Cancer Cell Migration and Angiogenesis by Regulating Vascular Endothelial Growth Factor Receptor 2/Extracellular Signal-Regulated Kinase 2 Pathways.

  Authors:Bai Xue, Hong Guo, and Ying TaoFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20223,351 words Article 1380LBreast cancer is the most common form of cancer in women in need for better treatment. Sophoridine, a plant-derived quinoxidine alkaloid, has been shown to exhibit pharmacological effects on several diseases including...

• Erianin Regulates PI3K/AKT Signaling Pathway and Inhibits Cell Invasion and Migration in Gastric Cancer In Vitro.

  Authors:Junwei Xu, Ning Qin, Wenbo Jiang, and Tao ChenFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20224,095 words Article 1370LGastric carcinoma is one of the most malignant cancers associated with lifestyle and genetics. The currently used pharmacotherapeutics are associated with serious side effects necessitating a need for safer drugs....

• Skullcapflavone II Alleviates Lipopolysaccharide-Induced Apoptosis and Inflammation in WI-38 Cells.

  Authors:Donglian Wang, Guoyong Hu, Lidong Zhao, Pengcheng Xing, Minjie Zhou, and Chao HanFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20222,996 words Article 1510LThe role of skullcapflavone II in pneumonia was investigated using lipopolysaccharide treated human lung fibroblasts WI-38 cells as a model. Lipopolysaccharide treatment led to decreased cell viability, increased cell...

• Bilobalide Improves Steroid-Induced Avascular Necrosis of the Femoral Head through PI3K/AKT Pathway.

  Authors:Bin Zhou, Guangfu Zhou, Wenzhou Zhang, Benshun Tang, Guochuan Wang, and Xiaolu ZhouFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20223,860 words Article 1260LSteroid-induced avascular necrosis of the femoral head is a metabolic disease that results from the use of glucocorticoid drugs, leading to impaired blood supply to the femoral head and death of bone cells and altered...

• Plantamajoside Inhibits the Growth of Acute Myeloid Leukemia Cells by Modulating NF-[kappa]B and PI3K/AKT Signaling Pathways.

  Authors:Xiaolu Zhou, Guochuan Wang, Qiongsheng Wu, and Mei YangFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20224,130 words Article 1470LAcute myeloid leukemia is a highly invasive and heterogeneous malignant tumor. Plantamajoside, a natural compound extracted from Plantago asiatica L., has been shown to exhibit the inhibitory effect on a variety of...

• Hesperidin Exherts Antiglaucoma Effects by Activating Overexpression of BMP4 Signaling and Management of Retinal Ganglionic Cells Degeneration.

  Authors:Lingli Wang, Yuping Li, Tao He, Lixia Cheng, Cong Zhou, and Feng ZhouFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20225,382 words Article 1390LWe investigated the effect of hesperidin on bone morphogenetic protein 4 signaling, which is involved in preventing retinal ganglion cell degeneration in rats with glaucoma. We investigated the therapeutic efficacy of...

• Optimization of the Kudzu Resistant Starch Preparation Based on Debranching and Recrystallization and its Structural Properties.

  Authors:Zhixiang Xue, Quancen Li, Hui Zhao, Bin Liu, Hongbo Song, and Feng ZengFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20224,905 words Article 1320LKudzu-resistant starch was prepared by pullulanase debranching recrystallization. Based on single factor experiments, the response surface optimization method was used to analyze the optimal conditions for the...

• Procyanidin A1 Inhibits Insulin Resistance and Oxidative Stress in Palmitic Acid Treated HepG2 Cells.

  Authors:Dan Yu, Jin Xu, Ya Chen, and Bimin ShiFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20223,218 words Article 1500LThe present study has examined the effect of procyanidin A1 on insulin resistance and oxidative stress in palmitic acid treated HepG2 cells. The HepG2 cells were pretreated with procyanidin A1 and then with palmitic...

• Jatrorrhizine Ameliorates Osteogenic Differentiation in Dexamethasone Induced MC3T3-E1 Cells by Regulating Histone Deacetylase 4.

  Authors:Ping Li, Qiming Yang, Lujue Dong, Dongli Zhang, and Qiuke XiaoFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20223,457 words Article 1310LOsteoporosis is an age-related disorder with enormous public health burden with an urgent need for better diagnosis and treatment. Herein, we have investigated the potential role of jatrorrhizine, a plant bioactive, in...

• The Effects of Bletilla striata Polysaccharides on Antioxidant and Immunomodulatory Activities of Mice In Vivo.

  Authors:X.M. He, C.W. Chen, F.C. Zhu, D.L. Qiao, N.F. Chen, and C. SongFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20225,578 words Article 1360LBletilla striata polysaccharide is a well-known antioxidant and immunomodulatory ingredient used in a variety of traditional Chinese medicine applications. A mouse aging model was constructed by intraperitoneal injection...

• Optimization of Conditions for Preparation of Ginger Essential Oil Microcapsules by Acid-Modified Palygorskite-Stabilized Pickering Emulsion Templating Methodology.

  Authors:Yu Deng, Na Xu, Xiaogeng Liu, Mei Xue, and Hong LeiFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20223,152 words Report 1460LUsing the acid-modified palygorskite-stabilized oil-in-water Pickering emulsion templating methodology, microencapsulation of ginger essential oil was prepared exploiting pectin and chitosan hydrochloride. To improve...

• Extraction, Preliminary Characterization, and Antioxidant Activity of Polysaccharides From Laetiporus Sulphureus Mushroom.

  Authors:Meixia Chen, Xinrong Zhong, Kunhuang Han, Shengrong Liu, Weirui Zhang, Fengfang Zhou, et al.From:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20225,327 words Article 1380LDue to its nutritional and medicinal properties, Laetiporus sulphureus has gained increased interest worldwide. The polysaccharides of L. sulphureus exhibit potentials as therapeutic agents for many chronic diseases. The...

• Antcin C Enhances Cellular Apoptosis of Hepatic Carcinoma Cells by Modulating Phosphoinositide 3-Kinases/Protein Kinase B/The Mammalian Target of Rapamycin Pathway.

  Authors:Zhenyu Ti, Xiaofeng Wang, Quanlin Xu, Xiaojun Wu, Wenhao Chen, and Man YanFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20224,234 words Article 1420LThe present study has evaluated the role of Antcin C in hepatic carcinoma and its possible mechanism of action. The results show that Antcin C causes a significant dose-dependent reduction in cell viability, cell...

• Casticin Alleviates the Proliferation and Extracellular Matrix Deposition in Glomerular Mesangial Cells Induced by High Levels of Glucose.

  Authors:Zheng Ma, Chen Xu, Zhenfan Wang, and Zheng ZhouFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20223,096 words Article 1330LDiabetic nephropathy is a common complication of diabetes associated with defects in the extracellular matrix. However, its precise mechanism remains to be explored. Casticin (3', 5-dihydroxy-3, 4', 6, 7-tetramethoxyl...

• Bergenin Alleviates Oxidative Stress and Apoptosis of Cardiomyocytes Induced by Oxygen-Glucose Deprivation Via Activating SIRT1/FOXO3a/MnSOD Pathway.

  Authors:Wangqiang Zhang and Rui ChaiFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20223,838 words Article 1320LWe have explored the effects of bergenin on oxidative stress and apoptosis of H9c2 cells induced by oxygen-glucose deprivation as an experimental model of acute myocardial infarction. The results of our studies show a...

• Alantolactone Suppresses Inflammation and Oxidative Stress in Doxorubicin Induced H9c2 Cells.

  Authors:Ying Yang and Tianwei GaoFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20223,348 words Article 1420LUse of alantolactone in traditional Chinese medicine has been reported in a wide variety of diseases. To explore the role of alantolactone in chronic heart failure, its effect on doxorubicin treated H9c2 cells as a model...

• Extraction and Antioxidant Activities of Polysaccharides Produced by Submerged Mycelia Culture of Oudemansiella raphanipes.

  Authors:Qi Wei, Fengfang Zhou, Binxin Cai, Shengrong Liu, Weirui Zhang, and Meixia ChenFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20224,483 words Article 1370LOudemansiella raphanipes is a commercially popular edible medicinal mushroom. The polysaccharides from O. raphanipes are the natural therapy for various metabolic diseases. Therefore, we have developed the optimal...

• Alantolactone Alleviates Rise in Markers of Periodontitis by Lipopolysaccharide in Human Periodontal Ligament Cells.

  Authors:Yaoqin Li, Jiaqi Sun, and Huajun ZhuFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20223,877 words Article 1460LAlantolactone, a natural sesquiterpene lactone, exerts its antiallergic, antibacterial, antimicrobial, antifungal, anticancer, and neuroprotective effects by virtue of its anti-inflammatory and antioxidant properties. We...

• Effects of 6-Month Supplementation with Multi-Component Herbal Supplement Phytodynamic[TM] on Mitochondrial Function, Telomere Length, and Chronic Inflammation in Adults Aged 65 Years and Older: A Pilot Trial.

  Authors:Nikola Todorovic, Darinka Korovljev, Valdemar Stajer, Nebojsa Maksimovic, Laszlo Ratgeber, Jozsef Betlehem, et al.From:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20223,193 words Article 1590LHerbal supplements are often used by elderly populations in aim to manage age-related traits; yet, most have shown limited benefits, keeping a quest for safe and effective longevity-promoting mixtures open. The main aim...

• Protective Effects of Onjisaponin B in a Mouse Model of Alzheimer's Disease via Enhancement of Hippocampal Neuroplasticity.

  Authors:Ling Zhang, Xiaoyu Zha, Gaowen Li, Qun Chen, and Qing XiaFrom:Current Topics in Nutraceutical Research (Vol. 20, Issue 3) Peer-Reviewed

  Aug. 20223,707 words Article 1340LAlzheimer's disease mainly affects elderly population leading to impairment in cogitation. A lack of clear understanding of the mechanism of Alzheimer's disease has led to a lack of definite therapeutic option. Herein we...