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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedWe appreciate the points raised by Burgoon and Borgert regarding our recent analysis of the U.S. Environmental Protection Agency's (EPA) data from the high-throughput (HT) H295R screening of 656 chemicals in...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedIntroduction Hand grip strength (HGS) is a powerful predictor of disability, morbidity, and mortality in middle-age and elderly subjects. Available evidence on the link between poor HGS and cigarette smoking (1)...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedBackground: Consensus on the etiology of 1991 Gulf War illness (GWI) has been limited by lack of objective individual- level environmental exposure information and assumed recall bias. Objectives: We investigated a...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-Reviewed
Invited Perspective: Causal Implications of Gene by Environment Studies Applied to Gulf War Illness.
The thirtieth anniversary of the 1991 Gulf War has just passed, and much knowledge has been gained about the etiology and pathobiology of Gulf War Illness (GWI) over this time. (1,2) However, questions still remain about... -
From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedWilliam Mack runs a translational science laboratory focused on inflammation and oxidative stress. Years ago, this interest led him on a path toward investigating inflammatory effects of airborne particulate matter,...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedThe article by Cardona and Rudel (2021) analyzed ToxCast results for the H295R steroidogenesis assays and reported that "296 chemicals increased [estradiol] (182) or [progesterone] (185), with 71 chemicals increasing...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedBenzene is a known human carcinogen, (1) so consumers should not expect to find it in personal care products. (2) Nevertheless, between April 2021 and April 2022, companies issued 11 recalls for hand sanitizers,...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedBackground: Paraquat (PQ) is a pesticide, exposure to which has been associated with an increased risk of Parkinson's disease; however, PQ transport mechanisms in the brain are still unclear. Our previous studies...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedMcPartland et al. (1) discussed the initial 10 risk assessments (RAs) conducted by the U.S. Environmental Protection Agency (EPA) under the 2016 revisions to the Toxic Substances Control Act (TSCA). They noted the...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedBackground: By-products are formed when disinfectants react with organic matter in source water. The most common class of disinfection byproducts, trihalomethanes (THMs), have been linked to bladder cancer. Several...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedSummary: Advances in technologies to measure a broad set of exposures have led to a range of exposome research efforts. Yet, these efforts have insufficiently integrated methods that incorporate genetic data to...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedWastewater provides a naturally composited biological sample that includes pathogens shed in feces, urine, blood, sputum, and vomit and that can be used to infer information about disease occurrence in the community....
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedBackground: Per- and polyfluoroalkyl substances (PFAS) are a large class of synthetic (man-made) chemicals widely used in consumer products and industrial processes. Thousands of distinct PFAS exist in commerce. The 2019...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedBackground: Abnormal placental development may result in adverse pregnancy outcomes and metabolic diseases in adulthood; however, it remains unknown whether and how xenobiotics affect human placentation. Objectives:...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedHuman exposure to per- and polyfluoroalkyl substances (PFAS) is ubiquitous. (1) Prenatal and early-life exposures to PFAS have been consistently associated with adverse health effects in children, especially metabolic...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedBackground: Sewage surveillance, by detecting SARS-CoV-2 virus circulation at the community level, has the potential to supplement individual surveillance for COVID-19. However, to date, there have been no reports about...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedEnviron Health Perspect. 130(3):034003 (2022), https://doi.org/10.1289/EHP11026 The image attribution in this article was incorrectly listed as [C] Prof. P.M. Motta, Sapienza University of Rome/Science. The correct...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedBackground: Household air pollution (HAP) from biomass fuel combustion remains a leading environmental risk factor for morbidity worldwide. Objective: Measure the effect of liquefied petroleum gas (LPG) interventions on...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedBackground: Research suggests environmental contaminants can impact metabolic health; however, high costs prohibit in vivo screening of putative metabolic disruptors. High-throughput screening programs, such as ToxCast,...
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From:Environmental Health Perspectives (Vol. 130, Issue 5) Peer-ReviewedThe U.S. Environmental Protection Agency (U.S. EPA) is charged with the Herculean task of critically assessing the safety of tens of thousands of chemicals. New methods that support improved efficiency and effectiveness...