Search Results

• • 14 

    Academic Journals

  • Sort by: sorttype.publication.date.desc Newest sorttype.publication.date.asc Oldest sorttype.relevance Relevance

• Select Association of vascular endothelial growth factor -2578C/A gene polymorphism in Chinese patients with colon cancer

  1

  Association of vascular endothelial growth factor -2578C/A gene polymorphism in Chinese patients with colon cancer

  Authors:Lin Zhang, Guohu Zhang, Peihong Wang, Jiaqing Gong, Yongkuan Cao, and Lijun TangFrom:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20112,823 words Report 1350LThe vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen involved in the process of angiogenesis, a crucial phase in tumor growth and metastasis. We carried out a case-control study to...
• Select A novel SnaPshot assay to detect genetic mutations related to iron metabolism

  2

  A novel SnaPshot assay to detect genetic mutations related to iron metabolism

  Authors:Stefania Bertoncini, Ruth Blanco-Rojo, Carlos Baeza, Eduardo Arroyo-Pardo, Maria Pilar Vaquero, and Ana Maria Lopez-ParraFrom:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20113,334 words Report 1400LThe minisequencing method is a cost-effective tool to study single-nucleotide polymorphisms in human disease. For this reason, a novel polymerase chain reaction multiplex SNaPshot reaction has been developed that...
• Select Insulin receptor H1085H C>T and insulin receptor substrate 1 G972R polymorphisms and prostate cancer risk: a pilot study

  3

  Insulin receptor H1085H C>T and insulin receptor substrate 1 G972R polymorphisms and prostate cancer risk: a pilot study

  Authors:Andrea Saracevic, Nora Nikolac, Ante Reljic, and Ana-Maria SimundicFrom:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20113,294 words Report 1390LBackground: In recent years, numerous studies have focused their attention on genes that are part of the insulin/ insulin-like growth factor 1 signaling pathway, such as the insulin receptor (INSR) and the insulin...
• Select "Insufficient evidence" isn't sufficient anymore

  4

  "Insufficient evidence" isn't sufficient anymore

  Authors:Kristin Baxter, Amanda Field, and Sharon F. TerryFrom:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20111,054 words Article 1600LONE OF THE MANY TECHNOLOGICAL ADVANCES made possible by the Human Genome Project is the development of robust genomic tests that evaluate multiple genetic variants or gene expression patterns. The progress from...
• Select Perceptions of population cystic fibrosis prenatal and preconception carrier screening among individuals with cystic fibrosis and their family members

  5

  Perceptions of population cystic fibrosis prenatal and preconception carrier screening among individuals with cystic fibrosis and their family members

  Authors:Susannah J. Maxwell, Gaenor Kyne, Caron Molster, Nigel M. Barker, Jacqueline Ormsby, and Peter O'LearyFrom:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20114,211 words Survey 1580LAim: Our study aimed to quantitatively explore the perceptions of individuals with cystic fibrosis (CF) and their family members toward population prenatal and preconception CF carrier screening, including perceived...
• Select Repeat-primed polymerase chain reaction in myotonic dystrophy type 2 testing

  6

  Repeat-primed polymerase chain reaction in myotonic dystrophy type 2 testing

  Authors:Jan Radvansky, Andrej Ficek, and Ludevit KadasiFrom:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20112,562 words Report 1460LMyotonic dystrophy type 1 (DM1) and type 2 (DM2) are the most common autosomal dominant neuromuscular disorders in adults. DM1 is caused by an unstable expansion of the (CTG)n repeat tract in the DMPK gene, whereas DM2...
• Select HER-2/neu gene codon 655 (Ile/Val) polymorphism in breast carcinoma patients

  7

  HER-2/neu gene codon 655 (Ile/Val) polymorphism in breast carcinoma patients

  Authors:Ezgi Sezgin, Feride Iffet Sahin, Mahmut Can Yagmurdur, and Beyhan DemirhanFrom:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20112,107 words Report 1410LAmplification and/or overexpression of HER-2/neu has been reported to be associated with poor prognosis in breast cancer. One single-nucleotide polymorphism at codon 655 indicates a guanine-to-adenine substitution...
• Select Methylenetetrahydrofolate reductase polymorphisms are related to male infertility in Brazilian men

  8

  Methylenetetrahydrofolate reductase polymorphisms are related to male infertility in Brazilian men

  Authors:Marcello Machado Gava, Elisangela de Oliveira Chagas, Bianca Bianco, Denise Maria Christofolini, Antonio Carlos Lima Pompeo, Sidney Glina, et al.From:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20112,751 words Report 1380LObjective: The objective of this study was to analyze the distribution of the methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms in idiopathic infertile Brazilian patients with nonobstructive...
• Select Evaluation of Aurora-A gene polymorphism and esophageal cancer risk in a South Indian population

  9

  Evaluation of Aurora-A gene polymorphism and esophageal cancer risk in a South Indian population

  Authors:Srinivas Chava, Vasavi Mohan, Nagarjuna Pasupuleti, Manolla Madhavi Latha, Imran Ali Khan, Pavani Upendram, et al.From:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20112,680 words Report 1420LAim: Aurora-A is a serine/threonine protein kinase that functions in centrosome maturation and spindle assembly and is involved in regulating chromosome segregation. It is amplified and overexpressed in several human...
• Select mRNA expressions of inducible nitric oxide synthase, endothelial nitric oxide synthase, and neuronal nitric oxide synthase genes in meningitis patients

  10

  mRNA expressions of inducible nitric oxide synthase, endothelial nitric oxide synthase, and neuronal nitric oxide synthase genes in meningitis patients

  Authors:Serdar Oztuzcu, Yusuf Ziya Igci, Ahmet Arslan, Ercan Sivasli, Esma Ozkara, Mehri Igci, et al.From:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20112,576 words Report 1320LMeningitis is an inflammation of the protective membranes covering the brain and spinal cord caused by bacteria, fungi, or viruses with various clinical symptoms. Although meningitis is not so prevalent, it remains the...
• Select Molecular characterization of 25 Chinese pedigrees with 21-hydroxylase deficiency

  11

  Molecular characterization of 25 Chinese pedigrees with 21-hydroxylase deficiency

  Authors:Yongguo Yu, Jian Wang, Xiaodong Huang, Ying Wang, Peirong Yang, Juan Li, et al.From:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20112,840 words Report 1390LCongenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders mainly caused by a defect in the steroid 21-hydroxylase gene (CYP21A2). In this study, we investigated the molecular defects of 25 Chinese...
• Select Molecular pathogenesis of endometriosis; toll-like receptor-4 A896G (D299G) polymorphism: a novel explanation

  12

  Molecular pathogenesis of endometriosis; toll-like receptor-4 A896G (D299G) polymorphism: a novel explanation

  Authors:Madhavi Latha, Sirisha Vaidya, Sireesha Mowa, Srinivas Chava, Sujatha Govindan, Suresh Govatati, et al.From:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20112,542 words Report 1430LBackground: Endometriosis is a distressing gynecological disorder. Toll-like receptor 4 (TLR4) is specific for recognition of the molecular pattern of gram-negative bacteria. TLR4 is present on the surface of...
• Select Characterization of Y-chromosomal short tandem repeat markers in Pakistani populations

  13

  Characterization of Y-chromosomal short tandem repeat markers in Pakistani populations

  Authors:Saima Siddiqi, Atika Mansoor, Sooda Usman, Muhammad Nasir, Khalid M. Khan, and Raheel QamarFrom:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20114,440 words Report 1450LThe Y chromosome microsatellite markers have been extensively used for population genetic studies and in individual identification and paternity testing in forensic medicine. In the present study, we report the data of...
• Select Rapid and cost-effective method for the detection of the c.533G > A mutation in the HEXA gene

  14

  Rapid and cost-effective method for the detection of the c.533G > A mutation in the HEXA gene

  Authors:Diogo Ribeiro, Ana Joana Duarte, and Olga AmaralFrom:Genetic Testing and Molecular Biomarkers (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20112,085 words Report 1350LTay-Sachs disease is a rare autosomal recessive neurodegenerative disorder that results from mutations in the HEXA gene, leading to b-hexosaminidase A (HexA) a subunit deficiency. An unusual variant of Tay-Sachs disease...