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From:Journal of Experimental & Clinical Cancer Research (Vol. 40, Issue 1) Peer-ReviewedMutant isocitrate dehydrogenase 1/2 (mIDH1/2) gain a novel function for the conversion of [alpha]-ketoglutarate ([alpha]-KG) to oncometabolite R-2-hydroxyglutarate (R-2-HG). Two molecular entities namely enasidenib...
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