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    Academic Journals

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• A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression.

  Authors:Wentao Liu, Dianyun Ren, Wei Xiong, Xin Jin, and Liang ZhuFrom:Journal of Experimental & Clinical Cancer Research (Vol. 41, Issue 1) Peer-Reviewed

  Jan. 26, 20229,064 words Article 1440LBackground Tyrosine kinase inhibitors (TKIs) alone and in combination with immune checkpoint inhibitors (ICIs) have been shown to be beneficial for the survival of metastatic renal cell carcinoma (mRCC) patients, but...

• Human embryonic mesenchymal lung-conditioned medium promotes differentiation to myofibroblast and loss of stemness phenotype in lung adenocarcinoma cell lines.

  Authors:Jordi Canals, Alfons Navarro, Cristina Vila, Josep M. Canals, Tania Díaz, Melissa Acosta-Plasencia, et al.From:Journal of Experimental & Clinical Cancer Research (Vol. 41, Issue 1) Peer-Reviewed

  Jan. 26, 20228,279 words Article 1490LBackground When genes responsible for normal embryonic development are abnormally expressed in adults, it can lead to tumor development. This can suggest that the same mechanism that controls embryonic differentiation...