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Academic Journals
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedAuthor(s): Sushree S. Sahoo 1 2, Victor B. Pastor 2, Charnise Goodings 1, Rebecca K. Voss 2, Emilia J. Kozyra 2 3, Amina Szvetnik 2, Peter Noellke 2, Michael Dworzak 4, Jan Starý 5, Franco Locatelli 6, Riccardo Masetti...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedIn a recent phase 3 randomized trial of 700 patients with advanced urothelial cancer (JAVELIN Bladder 100; NCT02603432), avelumab/best supportive care (BSC) significantly prolonged overall survival relative to BSC alone...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedWe take stock of who made headlines this year for enlightening or disappointing us in 2021. Author(s): Karen O'Leary 1 Author Affiliations: (1) Nature Medicine, The Nobel Prize awarders Most likely not to award...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedAuthor(s): Karen O'Leary 1 Author Affiliations: (1) Nature Medicine, N. Engl. J. Med. 384, 989-1002 (2021) Lancet 397, 971-984 (2021) Pharmacological interventions are recommended for certain people with...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedThe effectiveness of the coronavirus disease 2019 (COVID-19) BNT162b2 vaccine in preventing disease and reducing viral loads of breakthrough infections (BTIs) has been decreasing, concomitantly with the rise of the Delta...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedAnti-programmed death (PD)-1 (aPD1) therapy is an effective treatment for metastatic melanoma (MM); however, over 50% of patients progress due to resistance. We tested a first-in-class immune-modulatory vaccine...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedAuthor(s): Karen O'Leary 1 Author Affiliations: (1) Nature Medicine, U.S. Preventive Services Task...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedNew research can help policymakers make evidence-based decisions about the risks and benefits of in-person schooling; strategic use of the available data will be key to getting this right. Author(s): Elizabeth A....
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedAuthor(s): Martina Patone 1, Lahiru Handunnetthi 2 3, Defne Saatci 1, Jiafeng Pan 4, Srinivasa Vittal Katikireddi 5, Saif Razvi 6, David Hunt 7, Xue W. Mei 1, Sharon Dixon 1, Francesco Zaccardi 8, Kamlesh Khunti 8, Peter...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedmRNA technology may be uniquely positioned to tackle a major hurdle for HIV vaccines: the elicitation of broadly cross-reactive neutralizing antibodies. A preclinical study takes the first step toward this goal....
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedThe COVID-19 pandemic continued to rage in 2021, but this was increasingly an unequal pandemic, with rich countries receiving millions of doses of vaccine and ending lockdowns and travel bans. It was also a year when...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedAuthor(s): Karen O'Leary 1 Author Affiliations: (1) Nature Medicine, National Human Genome Research...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedDetection of neural signatures related to pathological behavioral states could enable adaptive deep brain stimulation (DBS), a potential strategy for improving efficacy of DBS for neurological and psychiatric disorders....
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedWe asked experts around the world what surprised them about SARS-CoV-2 and COVID-19, and what questions remain unanswered. Author(s): Mike May 1 Author Affiliations: (1) Freelance writer and editor, Seattle, USA...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedAuthor(s): Donnele Daley 1 , Vishnu R. Mani 1 , Navyatha Mohan 1 , Neha Akkad 1 , Atsuo Ochi 1 , Daniel W. Heindel 2 , Ki Buom Lee 1 , Constantinos P. Zambirinis 1 , Gautam S. D. Balasubramania Pandian 1 , Shivraj...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedIntracranial aneurysm (IA) rupture leads to subarachnoid hemorrhage, a sudden-onset disease that often causes death or severe disability. Although genome-wide association studies have identified common genetic variants...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedArtificial intelligence (AI) systems have increasingly achieved expert-level performance in medical imaging applications. However, there is growing concern that such AI systems may reflect and amplify human bias, and...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedAuthor(s): Vicky van der Togt 1 2 , Sammie Mcfarland 3 , Marta Esperti 4 , Elizabeth Semper 5 , Sara Citrenbaum 1 , Jeremy S. Rossman 1 6 Author Affiliations: (1) Research-Aid Networks, Chicago, USA (2) Long Covid...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedB-cell maturation antigen (BCMA) is a prominent tumor-associated target for chimeric antigen receptor (CAR)-T cell therapy in multiple myeloma (MM). Here, we describe the case of a patient with MM who was enrolled in the...
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From:Nature Medicine (Vol. 27, Issue 12) Peer-ReviewedAuthor(s): Karen O'Leary 1 Author Affiliations: (1) Nature Medicine, World Health Organizationhttps://www.who.int/news/item/06-10-2021-who-recommends-groundbreaking-malaria-vaccine-for-children-at-risk (2021)...