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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedIntroduction Analyses of clinical trial registries (CTRs) offer insights into methodological problems of published research studies, e.g., non-publication and outcome-switching. Here, we use CTRs as a tool to evaluate...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedBackground Extracellular vesicles (EVs) are considered as crucial players in a wide variety of biological processes. Although their importance in joint diseases or infections has been shown by numerous studies, much...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedTrans-generational immune priming involves the transfer of immunological experience, acquired by the parents after exposure to pathogens, to protect their progeny against infections by these pathogens. Such natural...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedListeria monocytogenes can cause listeriosis, and people with hypoimmunity such as pregnant women, infants and fetuses are at high risk of invasive infection. Although the incidence of listeriosis is low, the fatality...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedBackground COVID-19 is a global public health problem causing high mortality worldwide. This study aimed to assess time to death and predictors of mortality among patients hospitalized for COVID-19 in the Arsi zone...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedThe vast majority of human traits, including many disease phenotypes, are affected by alleles at numerous genomic loci. With a continually increasing set of variants with published clinical disease or biomarker...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedBackground Deep learning segmentation requires large datasets with ground truth. Image annotation is time consuming and leads to shortages of ground truth data for clinical imaging. This study is to investigate the...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedNon-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disorder worldwide and is increasing at an alarming rate. NAFLD is strongly associated with obesity and insulin resistance. The use of animal...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedAuthor(s): The PLOS ONE Editors After this article [1] was published, questions were raised about the methods, data validation, and raw data availability of the study. In light of these issues, PLOS ONE reassessed this...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedIntroduction In Bangladesh, injury is one of the leading causes of death and morbidity in children. All children under 5 years of age are at high risk for drowning though the risks are highest when children first learn...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedWe describe an algorithm to compute the extremal eigenvalues and corresponding eigenvectors of a symmetric matrix which is based on solving a sequence of Quadratic Binary Optimization problems. This algorithm is robust...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedBackground Anemia is a disorder by which the body's red blood cells are inadequate to fulfill The physiological needs of the body. The World Health Organization (WHO) defines anemia as having a hemoglobin (Hb) level of...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedBackground In 2018, the right to lawful abortion in the Republic of Ireland significantly expanded, and service provision commenced on 1 January, 2019. Community provision of early medical abortion to 9 weeks plus 6...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedLarge natural disturbances such as insect outbreaks and fire are important processes for biodiversity in forest landscapes. However, few methods exist for incorporating natural disturbances into conservation planning....
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedH5N1 virus (H5N1V) is highly contagious among birds and it was first detected in humans in 1997 during a poultry outbreak in Hong Kong. As the mechanism of its pathogenesis inside the host is still lacking, in this...