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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedAuthor(s): The PLOS ONE Editors Following the publication of this article [1], concerns were raised regarding the results presented in multiple figures. Specifically, The following data appear similar despite...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedDNA Topoisomerase II[alpha] (TOP2[alpha]/170) is an enzyme essential for proliferating cells. For rapidly multiplying malignancies, this has made TOP2[alpha]/170 an important target for etoposide and other clinically...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedBackground Recent experimental studies have suggested a potential link between cathepsin S (CTTS) and gastric adenocarcinoma progression. Herein, we aimed to evaluate the expression of CTTS in gastric adenocarcinoma in...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedBackground Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), caused by mutations in NOTCH3, is the most common cause of hereditary cerebral small vessel disease....
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedNon-structural protein 1 (NS1) is a glycoprotein component of dengue virus (DENV) that is essential for viral replication, infection and immune evasion. Immunization with NS1 has been shown to elicit antibody-mediated...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedBackground Low-back pain is one of the most common health conditions worldwide. It is defined as pain below the costal margin and above the inferior gluteal folds. Current guidelines recommend management of chronic...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedSince the first reported case of coronavirus disease 2019 (COVID-19) in China, SARS-CoV-2 has been spreading worldwide. Genomic surveillance of SARS-CoV-2 has had a critical role in tracking the emergence, introduction,...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedBackground Cutaneous leishmaniasis is a neglected tropical disease caused by Leishmania spp. and transmitted by female sandflies. Terrorism and counter-insurgency military operations in Federally Administered Tribal...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedAuthor(s): Sophie Groot Wassink, Jessica van Wingerden, Rob F. Poell Sophie Groot Wassink should be included as first author in the author byline. Their affiliation is 1: the Department of Human Resource Studies,...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedConsidering the widespread use of rabbits in research that potentially causes pain and discomfort and the limited number of pain assessment validated tools in this species, we aimed to develop and validate a scale of...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedObjective Parents' tracking of developmental milestones can assist healthcare providers with early detection of developmental delays and appropriate referrals to early intervention. Crowdsourcing is one way to update...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedLymph node culture-positive tuberculosis (LNTB+) is associated with increased mycobacterial antigen-induced pro-inflammatory cytokine production compared to LN culture-negative tuberculosis (LNTB-). However, the...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedMultimorbidity is a global research priority, yet relatively little is known about it in low and middle income countries. South Africa has the largest burden of HIV worldwide but also has a growing burden of...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedThe kallikrein-kinin system has been implicated in body weight and glucose homeostasis. Their major effectors act by binding to the kinin B2 and B1 receptors. It was assessed the role of the kinin B1 receptor in weight...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedA well-established agenda on the research output, impact, and structure of global scientific elites such as Nobel Prize laureates has generated interest in the scientific elites from developing countries. However, this...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedAuthor(s): The PLOS ONE Editors Following the publication of this article [1], concerns were raised that the mass spectrometry spectra presented in Fig 8 appear similar to the mass spectrometry spectra presented in Fig...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedViruses play critical roles in the dynamics of microbial communities. Lytic viruses, for example, kill significant fractions of autotrophic and heterotrophic microbes daily. The dynamic interplay between viruses and...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedSince its origin, the emergence of vector-borne infections has taken a toll on incalculable human lives. The use of chemical insecticides is one of the early known methods of vector control and although their use is...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedIntroduction More than 70% of new HIV infections in Asia occurred in eight countries in 2020: Cambodia, China, India, Indonesia, Myanmar, Nepal, Thailand, and Vietnam-with a rising incidence among men who have sex with...
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From:PLoS ONE (Vol. 17, Issue 5) Peer-ReviewedIntroduction Invasive meningococcal disease (IMD) is still an important cause of mortality in children and survivors can have significant long-term disabling sequelae. There are few prospective studies looking at the...