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• Award rate inequities in biomedical research.

  Authors:Alessandra Zimmermann, Richard Klavans, Heather M. Offhaus, Teri A. Grieb, and Caleb SmithFrom:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20225,234 words Report 1550LPurpose The analysis of existing institutional research proposal databases can provide novel insights into science funding parity. The purpose of this study was to analyze the relationship between race/ethnicity and...

• Integration of bioassay and non-target metabolite analysis of tomato reveals that [beta]-carotene and lycopene activate the adiponectin signaling pathway, including AMPK phosphorylation.

  Authors:Shinsuke Mohri, Haruya Takahashi, Maiko Sakai, Naoko Waki, Shingo Takahashi, Koichi Aizawa, et al.From:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20229,318 words Report 1370LAdiponectin, an adipokine, regulates glucose metabolism and insulin sensitivity through the adiponectin receptor (AdipoR). In this study, we searched for metabolites that activate the adiponectin signaling pathway from...

• Single-cell specific and interpretable machine learning models for sparse scChIP-seq data imputation.

  Authors:Steffen Albrecht, Tommaso Andreani, Miguel A. Andrade-Navarro, and Jean Fred FontaineFrom:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 202210,810 words Report 1570LMotivation Single-cell Chromatin ImmunoPrecipitation DNA-Sequencing (scChIP-seq) analysis is challenging due to data sparsity. High degree of sparsity in biological high-throughput single-cell data is generally handled...

• A commercial ARHGEF17/TEM4 antibody cross-reacts with Nuclear Mitotic Apparatus protein 1 (NuMA).

  Authors:Diogjena Katerina Prifti, Annie Lauzier, and Sabine EloweFrom:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20229,415 words Report 1480LThe Rho family Guanine nucleotide exchange factor (GEF) ARHGEF17 (also known as TEM4) is a large protein with only 3 annotated regions: an N-terminal actin-binding domain, a Rho-specific dbl homology (DH)- pleckstrin...

• Reciprocal recombination genomic signatures in the symbiotic arbuscular mycorrhizal fungi Rhizophagus irregularis.

  Authors:Ivan D. Mateus, Ben Auxier, Mam M. S. Ndiaye, Joaquim Cruz, Soon-Jae Lee, and Ian R. SandersFrom:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20229,754 words Report 1520LArbuscular mycorrhizal fungi (AMF) are part of the most widespread fungal-plant symbiosis. They colonize at least 80% of plant species, promote plant growth and plant diversity. These fungi are multinucleated and contain...

• The indirect impact of COVID-19 pandemic on the utilization of the emergency medical services during the first pandemic wave: A system-wide study of Tuscany Region, Italy.

  Authors:Vieri Lastrucci, Francesca Collini, Silvia Forni, Sara D'Arienzo, Valeria Di Fabrizio, Primo Buscemi, et al.From:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20226,866 words Report 1540LBackground Utilization of Emergency Medical Services (EMS) declined during COVID-19 pandemic, but most of the studies analyzed components of the EMS system individually. The study aimed to evaluate the indirect impact...

• Sepsis assessment and management in critically Ill adults: A systematic review.

  Authors:Mohammad Rababa, Dania Bani Hamad, and Audai A. HayajnehFrom:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20225,673 words Report 1550LBackground Early assessment and management of patients with sepsis can significantly reduce its high mortality rates and improve patient outcomes and quality of life. Objectives The purposes of this review are to:...

• Efficacy and safety of saroglitazar for the management of dyslipidemia: A systematic review and meta-analysis of interventional studies.

  Authors:Manik Chhabra, Kota Vidyasagar, Sai Krishna Gudi, Jatin Sharma, Rishabh Sharma, and Muhammed RashidFrom:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20225,793 words Report 1430LBackground and objective Saroglitazar is a newer antidiabetic agent approved to manage dyslipidemia. The objective is tevaluate the efficacy and safety profiles of saroglitazar in patients with dyslipidemia. Methods...

• The prevalence and causes of pediatric uncorrected refractive error: Pooled data from population studies for Global Burden of Disease (GBD) sub-regions.

  Authors:He Cao, Xiang Cao, Zhi Cao, Lu Zhang, Yue Han, and Changchun GuoFrom:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20227,177 words Report 1400LBackground There are limited systematic reviews on the prevalence of uncorrected refractive errors in children. We aimed to summarize the prevalence and causes of pediatric uncorrected refractive error (URE) from...

• Comparison of storage and lignin accumulation characteristics between two types of snow pea.

  Authors:Xuerui Li, Jinxiang Wang, Yunhui Qu, Yiping Li, Yasmin Humaira, Sajjad Muhammad, et al.From:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20224,762 words Report 1500LSnow pea is a very important vegetable, and its postharvest storage characteristics vary with species. Few studies on the differences in its storage characteristics are available. In this study, postharvest changes in...

• Microencapsulation of carvacrol as an efficient tool to fight Pseudomonas aeruginosa and Enterococcus faecalis biofilms.

  Authors:Samah Mechmechani, Adem Gharsallaoui, Alexandre Fadel, Khaled El Omari, Simon Khelissa, Monzer Hamze, et al.From:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20229,273 words Report 1440LBiofilms are involved in serious problems in medical and food sectors due to their contribution to numerous severe chronic infections and foodborne diseases. The high resistance of biofilms to antimicrobial agents makes...

• Divergent confidence intervals among pre-specified analyses in the HiSTORIC stepped wedge trial: An exploratory post-hoc investigation.

  Authors:Richard A. Parker, Catriona Keerie, Christopher J. Weir, Atul Anand, and Nicholas L. MillsFrom:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20227,586 words Report 1570LBackground The high-sensitivity cardiac troponin on presentation to rule out myocardial infarction (HiSTORIC) study was a stepped-wedge cluster randomised trial with long before-and-after periods, involving seven...

• A mathematical model of blood flow in a stenosed artery with post-stenotic dilatation and a forced field.

  Authors:Mallinath Dhange, Gurunath Sankad, Rabia Safdar, Wasim Jamshed, Mohamed R. Eid, Umesh Bhujakkanavar, et al.From:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20226,670 words Report 1530LArterial stenosis is a common cardiovascular disease that restricts blood flow. A stenotic blood vessel creates tangent stress pressure, which lessens the arterial side and causes an aneurysm. The primary purpose of this...

• Sparse representation of brain signals offers effective computation of cortico-muscular coupling value to predict the task-related and non-task sEMG channels: A joint hdEEG-sEMG study.

  Authors:Ahmadreza Keihani, Amin Mohammad Mohammadi, Hengameh Marzbani, Shahriar Nafissi, Mohsen Reza Haidari, and Amir Homayoun JafariFrom:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20227,733 words Report 1500LCortico-muscular interactions play important role in sensorimotor control during motor task and are commonly studied by cortico-muscular coherence (CMC) method using joint electroencephalogram-surface electromyogram...

• Agreement between maximum and mean handgrip strength measurements in cancer patients.

  Authors:Rayne de Almeida Marques, Vanusa Felício de Souza, Thainá Cezini do Rosario, Maria Rita Pereira da Silva Garcia, Taísa Sabrina Silva Pereira, José Luiz Marques-Rocha, et al.From:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20224,595 words Report 1510LBackground and aim Handgrip strength (HGS) can be used to identify probable sarcopenia, by measuring maximum strength and/or through the average of three measurements. This study analyzed the agreement between maximum...

• Predicting the HIV/AIDS epidemic and measuring the effect of AIDS Conquering Project in Guangxi Zhuang Autonomous Region.

  Authors:Shizhao Ma, Yi Chen, Xiulan Lai, Guanghua Lan, Yuhua Ruan, Zhiyong Shen, et al.From:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20228,151 words Report 1590LTo control the HIV/AIDS epidemics in Guangxi Zhuang Autonomous Region in China, Guangxi government launched the 5-year Guangxi AIDS Conquering Project (GACP, Phase I: 2010-2014, Phase II: 2015-2020). In the project,...

• Clinical and survival differences during separate COVID-19 surges: Investigating the impact of the Sars-CoV-2 alpha variant in critical care patients.

  Authors:Andrew I. Ritchie, Owais Kadwani, Dina Saleh, Behrad Baharlo, Lesley R. Broomhead, Paul Randell, et al.From:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20223,217 words Report 1600LA number of studies have highlighted physiological data from the first surge in critically unwell Covid-19 patients but there is a paucity of data describing emerging variants of SARS-CoV-2, such as B.1.1.7. We compared...

• An examination of autonomic and facial responses to prototypical facial emotion expressions in psychopathy.

  Authors:Philip Deming, Hedwig Eisenbarth, Odile Rodrik, Shelby S. Weaver, Kent A. Kiehl, and Michael KoenigsFrom:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 202211,079 words Report 1420LMeta-analyses have found that people high in psychopathy categorize (or "recognize") others' prototypical facial emotion expressions with reduced accuracy. However, these have been contested with remaining questions...

• Dyslipidemia and associated risk factors among HIV/AIDS patients on HAART in Asmara, Eritrea.

  Authors:Oliver Okoth Achila, Feven Abrhaley, Yafet Kesete, Feven Tesfaldet, Filmon Alazar, Lidya Fisshaye, et al.From:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 20225,992 words Article 1420LBackground Though the initiation of Highly Active Antiretroviral Therapy (HAART) has led to decreased HIV/AIDS related mortality, the regimen has been reported to be associated with lipid toxicities. Baseline data on...

• Explosive and implosive root concepts: An analysis of music moods rooted by two influential rap artists.

  Authors:Susumu Nagayama and Hitoshi MitsuhashiFrom:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 1, 202212,264 words Report 1450LThis study proposes the notion of "root concepts" in cultural production, defined as a novel style and mode that a creator expresses at the initial field development phase, and that has a great influence on subsequent...