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    Academic Journals

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• Efficacy and safety of a new ranibizumab biosimilar CKD-701 using a pro re nata treatment regimen in neovascular age-related macular degeneration: A phase 3 randomized clinical trial.

  Authors:Chang Ki Yoon, Jaeryung Oh, Kunho Bae, Un Chul Park, Kyung-Sang Yu, and Hyeong Gon YuFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20225,270 words Report 1460LPurpose This study aimed to establish the efficacy, safety, and immunogenicity equivalence of the proposed biosimilar CKD-701 with the reference ranibizumab in patients with treatment-naïve neovascular age-related...

• Risk factors for mechanical ventilation and ECMO in COVID-19 patients admitted to the ICU: A multicenter retrospective observational study.

  Authors:Ryo Takada, Tomonori Takazawa, Yoshihiko Takahashi, Kenji Fujizuka, Kazuki Akieda, and Shigeru SaitoFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20224,551 words Report 1430LBackground The primary purpose of this study was to investigate risk factors associated with the need for mechanical ventilation (MV) and extracorporeal membrane oxygenation (ECMO) in COVID-19 patients admitted to the...

• Extracellular vesicles from focal segmental glomerulosclerosis pediatric patients induce STAT3 activation and mesangial cell proliferation.

  Authors:Naile T. Pekkucuksen, Lauren P. Liu, Rasha Aly, Lawrence R. Shoemaker, and Abdel A. AlliFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20226,612 words Report 1480LIntroduction Primary focal segmental glomerulosclerosis (FSGS), a major cause of end-stage kidney disease (ESKD) in adolescents and young adults, is attributable to recognized genetic mutations in a minority of cases....

• Human behavior determinants of exposure to Anopheles vectors of malaria in Sumba, Indonesia.

  Authors:Ismail E. Rozi, Lepa Syahrani, Dendi H. Permana, Puji B. S. Asih, Anggi P. N. Hidayati, Sully Kosasih, et al.From:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20227,087 words Report 1560LMalaria vector control interventions in Sumba, Indonesia, have not been able to eliminate malaria. Human drivers of exposure to Anopheles bites were investigated as part of a larger clinical trial evaluating the impact...

• Cigarette smoking and associated factors among men in five South Asian countries: A pooled analysis of nationally representative surveys.

  Authors:Md Shariful Islam, Mamunur Rashid, Monaemul Islam Sizear, Raafat Hassan, Mahbubur Rahman, Sarker Masud Parvez, et al.From:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20225,658 words Report 1330LSmoking is one of the leading causes of premature deaths worldwide. The cigarette is the commonest form of tobacco smoking. This study investigated the factors associated with cigarette smoking among men in five South...

• Real-world assessment of the clinical utility of whole body .sup.18F-FDG PET/CT in the diagnosis of infection.

  Authors:Natalia Medvedeva, Christopher Radcliffe, Maricar Malinis, Ming-Kai Chen, and Marwan M. AzarFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20224,518 words Report 1670LFew studies have aimed to capture the full spectrum of .sup.18 fluorodeoxyglucose-positron emission tomography/computed tomography (.sup.18 F-FDG PET/CT) use for evaluation of infections in a real-world context. We...

• Effects of dietary supplementation with histidine and [beta]-alanine on blood plasma metabolome of broiler chickens at different ages.

  Authors:Julia Lackner, Vincent Hess, Achim Marx, Morteza Hosseini-Ghaffari, and Helga SauerweinFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20226,340 words Report 1390LHistidine is an essential amino acid for broiler chickens and a precursor for the dipeptides carnosine and anserine, but little information is available about its metabolism in modern, fast-growing broilers. We used...

• What is important for people with type 2 diabetes? A focus group study to identify relevant aspects for Patient-Reported Outcome Measures in diabetes care.

  Authors:Nura Abdel-Rahman, Orly Manor, Liora Valinsky, Ofri Mosenzon, Ronit Calderon-Margalit, and Sveta RobermanFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20227,763 words Report 1310LBackground Patient-Reported Outcome Measures (PROMs) aim to evaluate the quality of care based on the perspectives of patients rather than clinical indicators. Qualitative research is needed to identify these...

• Postoperative management of total elbow arthroplasty: Results of a European survey among orthopedic surgeons.

  Authors:Willemijn van Dam, Danielle Meijering, Martin Stevens, Alexander L. Boerboom, and Denise EygendaalFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20223,486 words Report 1370LBackground The number of complications after total elbow arthroplasty (TEA) is high and survival rates are low compared to hip and knee arthroplasties. The most common reason for revision is aseptic loosening, which...

• Enhanced recombinant protein production in CHO cell continuous cultures under growth-inhibiting conditions is associated with an arrested cell cycle in G1/G0 phase.

  Authors:Verónica Avello, Mauro Torres, Mauricio Vergara, Julio Berrios, Norma A. Valdez-Cruz, Cristian Acevedo, et al.From:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20227,442 words Report 1540LLow temperature and sodium butyrate (NaBu) are two of the most used productivity-enhancing strategies in CHO cell cultures during biopharmaceutical manufacturing. While these two approaches alter the balance in the...

• Spelling acquisition in a consistent orthography: The facilitatory effect of syllable frequency in novice spellers.

  Authors:Marika Iaia, Chiara Valeria Marinelli, Francesca Vizzi, and Paola AngelelliFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20226,117 words Report 1500LThis study investigates the effects of two sublexical variables, syllable frequency, and word length, in the spelling acquisition of novice spellers dealing with a transparent orthography, such as Italian. Two groups of...

• Influencing factor of COVID-19 vaccination trust and hesitancy in Wonju city, South Korea.

  Authors:Hocheol Lee, Eun Bi Noh, Ji Eon Kim, Juyeon Oh, and Eun Woo NamFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20224,419 words Report 1480LSocial capital (SC) has been documented to effectively reduce the spread of diseases, including COVID-19; however, research pertaining to SC and COVID-19 vaccination in Korea is lacking. This cross-sectional study...

• Trends and patterns of North Korea's disease burden from 1990 to 2019: Results from Global Burden of Disease study 2019.

  Authors:Eun Hae Lee, Minjae Choi, Joshua Kirabo Sempungu, and Yo Han LeeFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20225,726 words Report 1530LBackground Evidence for the trends and patterns of disease burden in North Korea is limited, and in-depth analysis based on several health outcomes for a better understanding remains challenging. Therefore, we aimed to...

• Down-regulation of hepatic expression of GHR/STAT5/IGF-1 signaling pathway fosters development and aggressiveness of HCV-related hepatocellular carcinoma: Crosstalk with Snail-1 and type 2 transforming growth factor-beta receptor.

  Authors:Mona A. Abu El-Makarem, Mariana F. Kamel, Ahmed A. Mohamed, Hisham A. Ali, Mahmoud R. Mohamed, Alaa El-Deen M. Mohamed, et al.From:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 202211,631 words Report 1420LBackground and aims So far, few clinical trials are available concerning the role of growth hormone receptor (GHR)/signal transducer and activator of transcription 5 (STAT5)/insulin like growth factor-1 (IGF-1) axis in...

• Structure learning enhances concept formation in synthetic Active Inference agents.

  Authors:Victorita Neacsu, M. Berk Mirza, Rick A. Adams, and Karl J. FristonFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 202216,795 words Report 1500LHumans display astonishing skill in learning about the environment in which they operate. They assimilate a rich set of affordances and interrelations among different elements in particular contexts, and form flexible...

• Work-life balance in physicians working in two emergency departments of a university hospital: Results of a qualitative focus group study.

  Authors:Samipa Pudasaini, Liane Schenk, Martin Möckel, and Anna SchneiderFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20228,264 words Report 1450LBy applying an explorative approach, we aimed to identify a wide set of challenges and opportunities for the compatibility of the work and life domains in emergency department (ED) physicians as well as their suggestions...

• Atractylodes lancea for cholangiocarcinoma: Modulatory effects on CYP1A2 and CYP3A1 and pharmacokinetics in rats and biodistribution in mice.

  Authors:Nadda Muhamad, Tullayakorn Plengsuriyakarn, and Kesara Na-BangchangFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20226,871 words Report 1450LAtractylodes lancea (Thunb.) DC. (A. lancea: AL) is a promising candidate for the treatment of cholangiocarcinoma (bile duct cancer). The study investigated (i) the propensity of capsule formulation of the standardized...

• Functional dissociation along the rostrocaudal axis of Japanese quail hippocampus.

  Authors:Chelsey C. Damphousse, Noam Miller, and Diano F. MarroneFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20225,397 words Report 1470LThe mammalian hippocampus (Hp) can be functionally segregated along its septotemporal axis, with involvement of dorsal hippocampus (dHp) in spatial memory and ventral hippocampus (vHp) in stress responses and emotional...

• Predictors of sputum culture conversion time among MDR/RR TB patients on treatment in a low-income setting.

  Author:Meiraf Daniel MesheshaFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20224,403 words Report 1370LObjective This study aimed to assess the time to first culture conversion and its predictors among MDR/RR-TB cases enrolled in Dilchora Hospital. Method A retrospective cohort study was conducted among MDR/RR TB...

• Textural feature based intelligent approach for neurological abnormality detection from brain signal data.

  Authors:Md. Nurul Ahad Tawhid, Siuly Siuly, Kate Wang, and Hua WangFrom:PLoS ONE (Vol. 17, Issue 11) Peer-Reviewed

  Nov. 14, 20227,915 words Report 1510LThe diagnosis of neurological diseases is one of the biggest challenges in modern medicine, which is a major issue at the moment. Electroencephalography (EEG) recordings is usually used to identify various neurological...