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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedBackground Polygenic risk scores (PRS) hold the promise to refine prognostication in hepatocellular cancer (HCC). The few available HCC PRS include germline risk variants identified among individuals of mostly European...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedBackground Pharmacovigilance reports have suggested that certain commonly used medications may trigger autoimmune diseases (ADs) and immune-mediated inflammatory diseases (IMIDs). We systematically reviewed the...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedThe growth of the digital economy has created new forms of inequality of opportunity. This paper studies whether the development of the digital economy expands the income gap between urban and rural areas from...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedObjective To explore experiences, needs and rehabilitation priorities of patients who had their stroke and the experiences of therapists managing stroke patients during the COVID-19 pandemic. Design Exploratory...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedBackground There is growing evidence of the anti-inflammatory effect of the anti-diabetic drug metformin and its use to reduce pain. However, we currently lack studies investigating whether metformin is associated with...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedGiven the growing influence of non-academic organizations in the policy sphere, it is important to investigate the evidence both produced by and relied on by these organizations. Using citation analysis, a methodology...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedIntroduction Neonatal hyperbilirubinemia (NH) is commonly diagnosed and managed by pediatricians in various clinical settings. The 2004 American Academy of Pediatrics (AAP) Clinical Practice Guideline on NH is widely...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedWe investigated the genetic structure of the freshwater fish Aphyocypris normalis, in 33 populations around Hainan Island and southern mainland China. Sequencing of the mitochondrial DNA (mtDNA) cytochrome b from 127...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedBackground Approximately seven to nine percent of couples of reproductive age do not get pregnant despite regular and unprotected sexual intercourse. Various psychosocial interventions for women and men with fertility...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedIntroduction Neonatal mortality is pervasive in developing countries like Ethiopia. Though the risk of neonatal mortality is preventable through consolidating simple, low-cost, and less time-consuming essential care,...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedA substantial body of evidence suggests that young people, including those at the crucial transition points between 16 and 24, now face severe mental health challenges. In this article, we analyse data from 10 waves of a...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedMesenchymal stem cell-derived exosomes regulate cell migration, proliferation, differentiation, and synthesis of the extracellular matrix, giving great potential for the treatment of different diseases. The...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedMolecular genetic techniques are an effective monitoring tool, but high-quality DNA samples are usually required. In this study, we compared three different protocols of DNA extraction: NaCl (saline); phenol-chloroform...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedThe present study aimed to prepare solid lipid-based nanoparticles (SLNs) using Precirol.sup.® ATO 5 as solid lipid and Poloxamer 188 and Tween 80 as surfactant and co-surfactant respectively, and SLNs-derived gel for...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedBackground About 70% of patients with advanced cancer experience pain. Few studies have investigated the use of healthcare in this population and the relationship between pain intensity and costs. Methods Adults...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedIntroduction Digital technology-based interventions have gained popularity over the last two decades, due to the ease with which they are scalable and low in implementation cost. Multicomponent health promotion...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedAlthough prednisolone is a routinely prescribed medication in dogs, there is a lack of information regarding prednisolone prescribing practices by veterinarians. This study aims to describe characteristics of dogs...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedJuxtapleural nodules were excluded from the segmented lung region in the Hounsfield unit threshold-based segmentation method. To re-include those regions in the lung region, a new approach was presented using...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedYucca aloifolia L. fruit (Yucca or Spanish bayonet, family Asparagaceae) is recognized for its purplish red color reflecting its anthocyanin content, which has a powerful antioxidant activity. This study aimed to...
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From:PLoS ONE (Vol. 18, Issue 2) Peer-ReviewedInfrared spectroscopy can quickly and non-destructively extract analytical information from samples. It can be applied to the authenticity identification of various Chinese herbal medicines, the prediction of the mixing...