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• A distinctive gene expression fingerprint in mentally retarded male patients reflects disease-causing defects in the histone demethylase KDM5C

  Authors:Lars R. Jensen, Heinz Bartenschlager, Sinitdhorn Rujirabanjerd, Andreas Tzschach, Astrid Numann, Andreas R. Janecke, et al.From:PathoGenetics (Vol. 3) Peer-Reviewed

  Feb. 2, 20105,533 words Report Background Mental retardation is a genetically heterogeneous disorder, as more than 90 genes for this disorder has been found on the X chromosome alone. In addition the majority of patients are non-syndromic in that...