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From:PeerJ (Vol. 9) Peer-ReviewedTarget of rapamycin (TOR) operates as a hub of the signal transduction that integrates nutrient and energy signaling to promote cell proliferation and growth through mediating the transcriptional and post-...
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From:PeerJ (Vol. 9) Peer-ReviewedAlthough liver cirrhosis and hepatocellular carcinoma are major consequences of hepatitis C (HCV), there has been an increasing number of studies examining extrahepatic manifestations, especially those caused by systemic...
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From:PeerJ (Vol. 9) Peer-ReviewedBackground Coastal ecosystems are blue infrastructures that support coastal resources and also aquaculture. Seagrass meadows, one of coastal ecosystems, provide substrates for epiphytic diatoms, which are food...
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From:PeerJ (Vol. 9) Peer-ReviewedBackground Lung adenocarcinoma (LUAD) is the most common histological type of lung cancers, which is the primary cause of cancer-related mortality worldwide. Growing evidence has suggested that tumor microenvironment...
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From:PeerJ (Vol. 9) Peer-ReviewedBackground Although the WW-domain-containing oxidoreductase (WWOX)/Hypoxia-inducible factor 1 (HIF1) pathway is a well-known regulator of cellular glucose and energy metabolism in pathophysiological processes, its role...