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    Academic Journals

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• Homologous recombination repair rathway and RAD54L in early-stage lung adenocarcinoma.

  Authors:Shaopeng Zheng, Lintong Yao, Fasheng Li, Luyu Huang, Yunfang Yu, Zenan Lin, et al.From:PeerJ (Vol. 9) Peer-Reviewed

  Feb. 16, 20214,935 words Article 1460LObjective The current study aims to identify the dysregulated pathway involved in carcinogenesis and the essential survival-related dysregulated genes among this pathway in the early stage of lung adenocarcinoma...

• Tissue inhibitor of metalloproteinase-1 (TIMP-1) as a prognostic biomarker in gastrointestinal cancer: a meta-analysis.

  Authors:Lili Qin, Yueqi Wang, Na Yang, Yangyu Zhang, Tianye Zhao, Yanhua Wu, et al.From:PeerJ (Vol. 9) Peer-Reviewed

  Feb. 16, 20216,419 words Article 1420LBackground Tissue inhibitor of metalloproteinase 1 (TIMP-1) has recently been shown to be dependent on or independent of Matrix metalloproteinases (MMPs) in its roles in tumorigenesis and progression. This appreciation...

• Sugarcane/peanut intercropping system improves physicochemical properties by changing N and P cycling and organic matter turnover in root zone soil.

  Authors:Xiumei Tang, Yixin Zhang, Jing Jiang, Xiuzhen Meng, Zhipeng Huang, Haining Wu, et al.From:PeerJ (Vol. 9) Peer-Reviewed

  Feb. 16, 202110,099 words Article 1450LBackground The sugarcane/peanut intercropping system is a specific and efficient cropping pattern in South China. Intercropping systems change the bacterial diversity of soils and decrease disease rates. It can not...

• Comparative transcriptome analysis of differentially expressed genes related to the physiological changes of yellow-green leaf mutant of maize.

  Authors:Tingchun Li, Huaying Yang, Yan Lu, Qing Dong, Guihu Liu, Feng Chen, et al.From:PeerJ (Vol. 9) Peer-Reviewed

  Feb. 16, 20218,245 words Article 1390LChlorophylls, green pigments in chloroplasts, are essential for photosynthesis. Reduction in chlorophyll content may result in retarded growth, dwarfism, and sterility. In this study, a yellow-green leaf mutant of maize,...

• Historical and current distribution ranges and loss of mega-herbivores and carnivores of Asia.

  Authors:Tariq Mahmood, Tuong Thuy Vu, Ahimsa Campos-Arceiz, Faraz Akrim, Shaista Andleeb, Muhammad Farooq, et al.From:PeerJ (Vol. 9) Peer-Reviewed

  Feb. 16, 20218,931 words Article 1490LEcosystem functioning is dependent a lot on large mammals, which are, however, vulnerable and facing extinction risks due to human impacts mainly. Megafauna of Asia has been declining for a long, not only in numbers but...

• Influence of periodontal treatment on blood microbiotas: a clinical trial.

  Authors:Wenyi Zhang, Yang Meng, Jin Jing, Yingtao Wu, and Shu LiFrom:PeerJ (Vol. 9) Peer-Reviewed

  Feb. 16, 20215,712 words Article 1330LObjective To investigate the effects of periodontal treatment on the abundance and diversity of blood microbiota. Methods and Materials Twenty-seven periodontitis patients were randomly allocated to a control group...

• An integrated analysis of lncRNA and mRNA expression profiles in the kidneys of mice with lupus nephritis.

  Authors:Juan Wang, Xiongfei Wu, Yafang Tu, Jianzhong Dang, Zhitao Cai, Wenjing Liao, et al.From:PeerJ (Vol. 9) Peer-Reviewed

  Feb. 16, 20217,028 words Article 1240LLong noncoding RNAs (lncRNAs) are persistently expressed and have been described as potential biomarkers and therapeutic targets in various diseases. However, there is limited information regarding lncRNA expression in...

• Predicting lung adenocarcinoma disease progression using methylation-correlated blocks and ensemble machine learning classifiers.

  Authors:Xin Yu, Qian Yang, Dong Wang, Zhaoyang Li, Nianhang Chen, and De-Xin KongFrom:PeerJ (Vol. 9) Peer-Reviewed

  Feb. 16, 20219,082 words Article 1340LApplying the knowledge that methyltransferases and demethylases can modify adjacent cytosine-phosphorothioate-guanine (CpG) sites in the same DNA strand, we found that combining multiple CpGs into a single block may...

• Immune function of miR-214 and its application prospects as molecular marker.

  Authors:Qiuyuan Wang, Yang Liu, Yiru Wu, Jie Wen, and Chaolai ManFrom:PeerJ (Vol. 9) Peer-Reviewed

  Feb. 16, 20217,252 words Article 1440LMicroRNAs are a class of evolutionary conserved non-coding small RNAs that play key regulatory roles at the post-transcriptional level. In recent years, studies have shown that miR-214 plays an important role in...

• Lower Locus Coeruleus MRI intensity in patients with late-life major depression.

  Authors:Andrés Guinea-Izquierdo, Mónica Giménez, Ignacio Martínez-Zalacaín, Inés del Cerro, Pol Canal-Noguer, Gerard Blasco, et al.From:PeerJ (Vol. 9) Peer-Reviewed

  Feb. 16, 20219,308 words Article 1520LBackground The locus coeruleus (LC) is the major noradrenergic source in the central nervous system. Structural alterations in the LC contribute to the pathophysiology of different neuropsychiatric disorders, which may...

• Quantile-dependent expressivity of serum C-reactive protein concentrations in family sets.

  Author:Paul T. WilliamsFrom:PeerJ (Vol. 9) Peer-Reviewed

  Feb. 16, 202112,421 words Article 1600LBackground "Quantile-dependent expressivity" occurs when the effect size of a genetic variant depends upon whether the phenotype (e.g., C-reactive protein, CRP) is high or low relative to its distribution. We have...

• Determining novel candidate anti-hepatocellular carcinoma drugs using interaction networks and molecular docking between drug targets and natural compounds of SiNiSan.

  Authors:Qin Zhang, Zhangying Feng, Mengxi Gao, and Liru GuoFrom:PeerJ (Vol. 9) Peer-Reviewed

  Feb. 16, 20217,157 words Article 1530LBackground SiNiSan (SNS) is an ancient traditional Chinese medicine (TCM) used to treat liver and spleen deficiencies. We studied the unique advantages of using SNS to treat hepatocellular carcinoma (HCC) with multiple...

• Thick bark can protect trees from a severe ambrosia beetle attack.

  Authors:John M. Boland and Deborah L. WoodwardFrom:PeerJ (Vol. 9) Peer-Reviewed

  Feb. 16, 20218,391 words Article 1480LThick bark has been shown to protect trees from wildfires, but can it protect trees from an ambrosia beetle attack? We addressed this question by examining the distribution of holes of the invasive Kuroshio Shot Hole...