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From:PeerJ (Vol. 9) Peer-ReviewedIntroduction Thyroid cancer is a very common malignant tumor in the endocrine system, while the incidence of papillary thyroid carcinoma (PTC) throughout the world also shows a trend of increase year by year. In this...
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From:PeerJ (Vol. 9) Peer-ReviewedBackground Cancer is a disease of abnormal cell proliferation caused by abnormal expression of cancer-related genes. However, it is still difficult to distinguish benign and malignant lesions in many cases. KIF4A has...
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From:PeerJ (Vol. 9) Peer-ReviewedThe CRISPR-Cas9 system has recently evolved as a powerful mutagenic tool for targeted genome editing. The impeccable functioning of the system depends on the optimal design of single guide RNAs (sgRNAs) that mainly...
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From:PeerJ (Vol. 9) Peer-ReviewedBackground Damming disrupts rivers and destroys neighboring terrestrial ecosystems through inundation, resulting in profound and long-lasting impacts on biodiversity and ecosystem processes far beyond the river system...