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    Academic Journals

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• Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.

  Authors:Linluo Zhang, Changqing Li, Ling Fu, Zhichao Yu, Gengrui Xu, Jie Zhou, et al.From:PeerJ (Vol. 10) Peer-Reviewed

  Jan. 5, 20226,220 words Article 1330LCatalpol significantly reduces triptolide-induced hepatotoxicity, which is closely related to autophagy. The aim of this study was to explore the unclear protective mechanism of catalpol against triptolide. The...

• Genome-wide sequence identification and expression analysis of N.sup.6 -methyladenosine demethylase in sugar beet (Beta vulgaris L.) under salt stress.

  Authors:Jie Cui, Junli Liu, Junliang Li, Dayou Cheng, and Cuihong DaiFrom:PeerJ (Vol. 10) Peer-Reviewed

  Jan. 5, 20226,204 words Article 1310LIn eukaryotes, N.sup.6 -methyladenosine (m.sup.6 A) is the most abundant and highly conserved RNA modification. In vivo, m.sup.6 A demethylase dynamically regulates the m.sup.6 A level by removing the m.sup.6 A marker...

• Beyond the prey: male spiders highly invest in silk when producing worthless gifts.

  Authors:Camila Pavón-Peláez, Valentina Franco-Trecu, Irene Pandulli-Alonso, Therésa M. Jones, and Maria J. AlboFrom:PeerJ (Vol. 10) Peer-Reviewed

  Jan. 5, 20227,629 words Article 1420LIn the spider Paratrechalea ornata, males have two gift-giving mating tactics, offering either a nutritive (prey) or a worthless (prey leftovers) silk wrapped gift to females. Both gift types confer similar mating...

• Cancer types with high numbers of driver events are largely preventable.

  Authors:Aleksey V. Belikov and Sergey V. LeonovFrom:PeerJ (Vol. 10) Peer-Reviewed

  Jan. 5, 20224,909 words Article 1530LThere is a long-standing debate on whether cancer is predominantly driven by extrinsic risk factors such as smoking, or by intrinsic processes such as errors in DNA replication. We have previously shown that the number...

• Effectiveness of antifungal treatments during chytridiomycosis epizootics in populations of an endangered frog.

  Authors:Roland A. Knapp, Maxwell B. Joseph, Thomas C. Smith, Ericka E. Hegeman, Vance T. Vredenburg, James E. Erdman Jr, et al.From:PeerJ (Vol. 10) Peer-Reviewed

  Jan. 5, 202213,501 words Article 1490LThe recently-emerged amphibian chytrid fungus Batrachochytrium dendrobatidis (Bd) has had an unprecedented impact on global amphibian populations, and highlights the urgent need to develop effective mitigation...

• Genome-wide identification and expression analyses of C2H2 zinc finger transcription factors in Pleurotus ostreatus.

  Authors:Qiangqiang Ding, Hongyuan Zhao, Peilei Zhu, Xiangting Jiang, Fan Nie, and Guoqing LiFrom:PeerJ (Vol. 10) Peer-Reviewed

  Jan. 5, 20225,973 words Article 1320LThe C2H2-type zinc finger proteins (C2H2-ZFPs) regulate various developmental processes and abiotic stress responses in eukaryotes. Yet, a comprehensive analysis of these transcription factors which could be used to find...

• Increased mutation efficiency of CRISPR/Cas9 genome editing in banana by optimized construct.

  Authors:Sen Zhang, Shaoping Wu, Chunhua Hu, Qiaosong Yang, Tao Dong, Ou Sheng, et al.From:PeerJ (Vol. 10) Peer-Reviewed

  Jan. 5, 20226,920 words Article 1470LThe CRISPR/Cas9-mediated genome editing system has been used extensively to engineer targeted mutations in a wide variety of species. Its application in banana, however, has been hindered because of the species' triploid...

• Highly divergent isolates of chrysanthemum virus B and chrysanthemum virus R infecting chrysanthemum in Russia.

  Authors:Sergei N. Chirkov, Anna Sheveleva, Anastasiya Snezhkina, Anna Kudryavtseva, George Krasnov, Alexander Zakubanskiy, et al.From:PeerJ (Vol. 10) Peer-Reviewed

  Jan. 5, 20227,601 words Article 1370LBackground Chrysanthemum is a popular ornamental and medicinal plant that suffers from many viruses and viroids. Among them, chrysanthemum virus B (CVB, genus Carlavirus, family Betaflexiviridae) is widespread in all...

• Prior exposure to weathered oil influences foraging of an ecologically important saltmarsh resident fish.

  Authors:Ashley M. McDonald, Charles W. Martin, Guillaume Rieucau, and Brian J. RobertsFrom:PeerJ (Vol. 10) Peer-Reviewed

  Jan. 5, 20228,771 words Article 1770LEstuarine ecosystem balance typically relies on strong food web interconnectedness dependent on a relatively low number of resident taxa, presenting a potential ecological vulnerability to extreme ecosystem disturbances....

• Identification of FEZ2 as a potential oncogene in pancreatic ductal adenocarcinoma.

  Authors:Chaozhi Yang, Xuebing Wang, Chenjie Qiu, Ziruo Zheng, Kai Lin, Min Tu, et al.From:PeerJ (Vol. 10) Peer-Reviewed

  Jan. 5, 20227,029 words Article 1370LPancreatic ductal adenocarcinoma (PDAC) is one of the common malignant tumors with high lethal rate and poor prognosis. Dysregulation of many genes have been reported to be involved in the occurrence and development of...

• Salivary miRNAs as non-invasive biomarkers of hepatocellular carcinoma: a pilot study.

  Authors:Arshiya Mariam, Galen Miller-Atkins, Amika Moro, Alejandro I. Rodarte, Shirin Siddiqi, Lou-Anne Acevedo-Moreno, et al.From:PeerJ (Vol. 10) Peer-Reviewed

  Jan. 5, 20228,292 words Clinical report 1450LBackground Improved detection of hepatocellular carcinoma (HCC) is needed, as current detection methods, such as alpha fetoprotein (AFP) and ultrasound, suffer from poor sensitivity. MicroRNAs (miRNAs) are small,...

• Discovery of potential protein biomarkers associated with sugarcane white leaf disease susceptibility using a comparative proteomic approach.

  Authors:Kantinan Leetanasaksakul, Sittiruk Roytrakul, Narumon Phaonakrop, Suthathip Kittisenachai, Siriwan Thaisakun, Nitiya Srithuanok, et al.From:PeerJ (Vol. 10) Peer-Reviewed

  Jan. 5, 20225,006 words Article 1490LSugarcane white leaf disease (SCWLD) is caused by phytoplasma, a serious sugarcane phytoplasma pathogen, which causes significant decreases in crop yield and sugar quality. The identification of proteins involved in the...

• A critical review on modulators of Multidrug Resistance Protein 1 in cancer cells.

  Authors:Vivian Osei Poku and Surtaj Hussain IramFrom:PeerJ (Vol. 10) Peer-Reviewed

  Jan. 5, 202210,329 words Article 1480LMultidrug resistance protein 1 (MRP1/ABCC1) is an ATP-dependent efflux transporter, and responsible for the transport of a broad spectrum of xenobiotics, toxins, and physiological substrates across the plasma membrane....