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Academic Journals
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From:Reactions Weekly (Issue 1333)[S] Two patients developed encephalopathy following treatment with metronidazole [routes not stated]. Patient 1, a 74-year-old women with diabetes mellitus, developed gait disturbance, worsening dysarthria, and...
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From:Reactions Weekly (Issue 1333)A 50-year-old woman with carbohydrate intolerance and breast cancer had been receiving gabapentin and tamoxifen for 6 months when she presented with facial lesions which had appeared over the past month [dosages and...
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From:Reactions Weekly (Issue 1333)[S] A 64-year-old man developed various toxicities, including fluid retention, leucopenia and Herpes simplex folliculitis during everolimus therapy for malignant insulinoma. The man, who had been diagnosed with...
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From:Reactions Weekly (Issue 1333)[S] A 46-year-old woman with underlying congenital thrombophilia and Behcet's disease developed haemarthrosis during anticoagulant therapy with warfarin. The woman, who had been receiving oral warfarin [dosage not...
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From:Reactions Weekly (Issue 1333)[S] A 6-year-old girl developed lymphoblastic lymphoma following treatment with insulin aspart and insulin suspension isophane for type 1 diabetes mellitus. The girl, who had an 18-month history of type 1 diabetes...
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From:Reactions Weekly (Issue 1333)Four men who were bodybuilders aged 24-37 years were evaluated for jaundice and pruritus, following the use of over-the-counter anabolic steroid supplements [dosages and routes not stated] to boost testosterone for a...
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From:Reactions Weekly (Issue 1333)Unsettled scientific debate about the association between statins and cancer led investigators from the UK and the US to assess whether cancer can be attributed to stain use among a general population of older adults....
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From:Reactions Weekly (Issue 1333)The US FDA is recommending removing the breast cancer indication from the Avastin [bevacizumab] label because the balance of benefits and risks does not support the use of Avastin for this indication. (1) This decision...
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From:Reactions Weekly (Issue 1333)Two women with type 2 diabetes received insulins and developed hypersensitivity reactions, which were successfully managed with desensitisation. A 49-year-old woman received regular recombinant human insulin by...
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From:Reactions Weekly (Issue 1333)[S] A 74-year-old man developed parkinsonism and neuroleptic malignant syndrome during treatment with antipsychotics. The man was referred to a psychogeriatric inpatient unit with a 1 month history of depressed...
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From:Reactions Weekly (Issue 1333)An 82-year-old woman developed hypersensitivity following administration of Tc-99m albumin for sentinel lymph node identification. The woman had recently undergone surgery for tumour excision, which confirmed grade 2...
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From:Reactions Weekly (Issue 1333)[S] An elderly man developed concurrent Epstein-Barr virus-positive Hodgkin lymphoma and plasmablastic lymphoma following fludarabine therapy for chronic lymphocytic lymphoma (CLL). The man, who had been diagnosed...
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From:Reactions Weekly (Issue 1333)Long-term use of anticholinergic agents "has no significant effect on mortality or the occurrence of adverse cardiovascular events" among patients with chronic obstructive pulmonary disease (COPD), concludes a team of...
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From:Reactions Weekly (Issue 1333)However, a review by the EMA's CHMP has determined that the benefits of Avastin still outweigh its risks when it is used in combination with paclitaxel for metastatic breast cancer--but not other treatments. (2)...
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From:Reactions Weekly (Issue 1333)[S] A 4-year-old boy developed an anaphylactic reaction during treatment with cyclopentolate for an examination under cycloplegia. The boy received three drops of cycloplegic eye drops [Sikloplejin] containing...
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From:Reactions Weekly (Issue 1333)[S] An 88-year-old man developed a spinal epidural haematoma during long-term warfarin therapy for atrial fibrillation; he subsequently died. The man had been receiving oral warfarin [Coumadin] 5 mg/day for 5...
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From:Reactions Weekly (Issue 1333)[S] An elderly man with metastatic renal cell carcinoma (RCC) developed thrombocytopenia and severe erythrodysaesthesia following second-line chemotherapy with sorafenib [Nexavar], and fatigue with fever with...
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From:Reactions Weekly (Issue 1333)[S] A 50-year-old woman developed transient paraplegia after a caudal injection of bupivacaine and butorphanol was inadvertently administered intrathecally. The woman, who had L4-L5 grade II lytic...
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From:Reactions Weekly (Issue 1333)Five men and five women, aged 38-88 years, experienced hypersensitivity reactions during treatment with rifampicin (seven patients) or isoniazid (3) for mycobacterial infections, and failed desensitisation protocols;...
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From:Reactions Weekly (Issue 1333)[S] A 39-year-old pregnant woman developed thrombocytopenia and thrombosis during treatment with enoxaparin sodium. The woman started SC enoxaparin sodium 40 mg/day injections after being admitted with threatened...