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Academic Journals
- 150
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From:Reactions Weekly (Issue 1336)An increase in the risk of intracranial haemorrhage has been found in stroke patients who received vorapaxar while enrolled in the TRA-2A * and TRACER ** clinical trials. (1, 2) As a result, Merck is making changes...
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From:Reactions Weekly (Issue 1336)[S] Four patients with chronic myeloid leukaemia (CML), three female and one male [ages not stated], developed asymptomatic peripheral blood lymphocytosis during treatment with dasatinib; these patients were...
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From:Reactions Weekly (Issue 1336)[S] A 62-year-old man experienced a stroke following treatment with immune globulin for Guillain-Barre syndrome (GBS). The man was first hospitalised after developing leg weakness, which later spread to his arms...
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From:Reactions Weekly (Issue 1336)[S] A 71-year-old man developed systemic granulomatous disease and syndrome of inappropriate antidiuretic hormone (SIADH) during treatment with BCG for bladder cancer. He later died. The man was admitted with...
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From:Reactions Weekly (Issue 1336)[*][S] A 3-year-11-month-old boy developed acute encephalopathy associated with carnitine deficiency following administration of cefteram pivoxil for the prevention of urinary tract infections. The boy, who had...
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From:Reactions Weekly (Issue 1336)[*][X] A male patient [age not stated] with benign prostate hyperplasia, had been receiving finasteride [dosage and route not stated] with successful control of his PSA levels for several years. He started receiving...
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From:Reactions Weekly (Issue 1336)[S] Three patients developed hepatotoxicity during treatment with either amoxicillin/clavulanic acid [dosages and routes not stated] or ceftriaxone. A 72-year-old woman presented with pruritus and jaundice in...
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From:Reactions Weekly (Issue 1336)A man developed hepatitis E during treatment with sirolimus and tacrolimus for post-transplant immunosuppression. The man received two islet transplants for type 1 diabetes at 36 years of age and began...
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From:Reactions Weekly (Issue 1336)[S] Two children, who had congenital heart disease, developed pulmonary hypertensive crisis following ketamine administration during transcatheter occlusion surgery. A 4-year-old 15kg boy received IV ketamine 2...
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From:Reactions Weekly (Issue 1336)A 61-year-old woman with possible recurrence of breast cancer underwent a PET scan with fludeoxyglucose F-18 [FDG; drug details not stated], and a high intensity focus in the apical segment of her lower lobe of her left...
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From:Reactions Weekly (Issue 1336)A 23-year-old woman with Wilson's disease developed elastosis perforans serpiginosa and cutis laxa following long-term treatment with penicillamine. The woman had been diagnosed with Wilson's disease at 4 years of...
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From:Reactions Weekly (Issue 1336)[S] A 43-year-old woman developed a haematoma following a sodium hypochlorite accident [details of drug administration not stated]. The woman was transferred to the emergency department with progressive facial...
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From:Reactions Weekly (Issue 1336)[S] A 65-year-old man experienced manic and psychotic symptoms following treatment with leuprorelin for prostate cancer. The man was taken to hospital by police after his wife reported that he was extremely...
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From:Reactions Weekly (Issue 1336)[O][S] Three patients developed intraocular toxicity including cataracts, retinal detachment and panophthalmitis following inadvertent high-dose amphotericin B. An 11-year-old boy with post-traumatic...
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From:Reactions Weekly (Issue 1336)A 79-year-old man with metastatic cutaneous squamous cell carcinoma initiated a 4-week cycle of cetuximab [route not stated]. His regimen consisted of cetuximab 400 mg/[m.sup.2] infusions on day 1 of therapy followed by...
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From:Reactions Weekly (Issue 1336)Following the report of several cases of liver injury, including two cases of liver failure, in patients receiving dronedarone [Multaq], * the European Commission has requested that the EMA's CHMP conducts a review...
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From:Reactions Weekly (Issue 1336)[S] Five children developed immediate-type hypersensitivity reactions following prednisolone or betamethasone administration [dosages not stated]. A 9-year-old boy received IV prednisolone succinate for a local...
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From:Reactions Weekly (Issue 1336)[S] A 16-year-old multiple organ transplant recipient [sex not stated] developed zygomycosis during immunosuppressive and antifungal treatment [routes not stated; dosage information incomplete; duration of treatments...
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From:Reactions Weekly (Issue 1336)[S] A retrospective study identified 11 patients who developed acute pancreatitis during treatment with azathioprine or mercaptopurine [see table]. Of these, eight women, aged 18-53 years, had been receiving...
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From:Reactions Weekly (Issue 1336)[S] A 63-year-old man developed cytomegalovirus (CMV) pneumonia during treatment with cyclophosphamide, methylprednisolone and prednisolone for Goodpasture's syndrome (GPS). The man, with a history of blood in his...