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From:Stem Cells International (Vol. 2019) Peer-ReviewedThe human endometrial stromal cells (hEndoSCs) could maintain endometrial homeostasis and play a critical role in repairing endometrial injury. Mesenchymal stem cells (MSCs) significantly increase the proliferation of...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedCell therapy for central nervous system (CNS) disorders is beginning to prove its safety and efficiency. Intraparenchymal transplantation can be an option for cell delivery; however, one concern regarding this method is...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedRegenerative medicine literature has proposed mesenchymal stem/progenitor cell- (MSC-) mediated therapeutic approaches for their great potential in managing various diseases and tissue defects. Dental MSCs represent...
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From:Stem Cells International (Vol. 2019) Peer-Reviewed3D bioprinting offers interesting opportunities for 3D tissue printing by providing living cells with appropriate scaffolds with a dedicated structure. Biological advances in bioinks are currently promising for cell...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedTo date, the decellularized scaffold has been widely explored as a source of biological scaffolds for regenerative medicine. However, the acellular matrix derived from natural tissues and organs has a lot of defects,...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedInflammation is part of a complex biological response to injury that mediates a rapid mobilization of cells and triggers the restoration of tissue homeostasis. The systemic diseases of the connective tissues, repetitive...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedTherapeutic treatment of various inflammation-related diseases using mesenchymal stem cells (MSCs) has increased in recent years because of the paracrine action of these cells but shows several limitations. First,...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedLarge prefabricated flaps often suffer from necrosis or poor healing due to a lack of new blood vessels and related factors that promote angiogenesis. The innovative use of adipose-derived stem cell exosomes (ADSC-Exo)...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedBackground. Adipose tissue-derived stromal cells (ADSCs) have great potential for cell-based therapies, including tissue engineering. However, various factors can influence the characteristics of isolated ADSCs. Methods....
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From:Stem Cells International (Vol. 2019) Peer-ReviewedLiver fibrosis is the excessive extracellular matrix accumulation of proteins, such as collagen, which follows the chronic liver diseases. Advanced liver fibrosis leads to cirrhosis and liver failure. Nilotinib is a...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedCd14 and Alpk1 both encode pathogen recognition receptors and are known candidate genes for affecting severity in inflammatory bowel diseases. CD14 acts as a coreceptor for bacterial lipopolysaccharide (LPS), while ALPK1...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedDental tissue has been acknowledged as an advantaged source for high-quality dental pulp stem cell (DPSC) preparation. However, despite the accomplishment of the separation of DPSCs from permanent teeth and supernumerary...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedMillions of plastic surgeries are performed worldwide every year with the objective of correcting lipodystrophies stemming from lesions, tumor resections, birth defects, and AIDS-associated antiretroviral therapy....
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From:Stem Cells International (Vol. 2019) Peer-ReviewedEx vivo grown human corneal endothelial cells (HCEnC) are a new emerging treatment option to treat visually impaired patients aimed at alleviating the current global donor shortage. Expanding HCEnC is still challenging,...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedIn the article titled "Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients" [1], there were errors in...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedObjective. Parathyroid hormone (PTH) is considered to be essential during the tooth development. Stem cells from the apical papilla (SCAPs) are responsible for dentine formation. However, the interaction between PTH and...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedMicrophthalmia-associated transcription factor (MITF), a basic helix-loop-helix leucine zipper transcription factor, can govern gene expression by binding to E box elements in the promoter region of its target gene....
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From:Stem Cells International (Vol. 2019) Peer-ReviewedObjective. This research is aimed at investigating how high glucose affects the proliferation and apoptosis in periodontal ligament stem cells (PDLSCs) in the presence of TNF-[alpha]. Methods. PDLSCs obtained from...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedTwo of the main problems of stem cell and regenerative medicine are the exit of pluripotency and differentiation to functional cells or tissues. The answer to these two problems holds great value in the clinical...
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From:Stem Cells International (Vol. 2019) Peer-ReviewedStem cell therapy provides new insights for the treatment of diseases or disorders that cannot yet be successfully managed through conventional care. Current cell-based approaches are mainly focused on the use of...