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    Academic Journals

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• Bone Defect Repair Using a Bone Substitute Supported by Mesenchymal Stem Cells Derived from the Umbilical Cord.

  Authors:Michal Kosinski, Anna Figiel-Dabrowska, Wioletta Lech, Lukasz Wieprzowski, Ryszard Strzalkowski, Damian Strzemecki, et al.From:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20207,654 words Article 1350LObjective. Bone defects or atrophy may arise as a consequence of injury, inflammation of various etiologies, and neoplastic or traumatic processes or as a result of surgical procedures. Sometimes the regeneration process...

• The Achievements and Challenges of Mesenchymal Stem Cell-Based Therapy in Inflammatory Bowel Disease and Its Associated Colorectal Cancer.

  Authors:Dickson Kofi Wiredu Ocansey, Wei Qiu, Jingyan Wang, Yongmin Yan, Hui Qian, Xu Zhang, et al.From:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 202011,861 words Article 1620LApproximately 18.1x[10.sup.6] new cases of cancer were recorded globally in 2018, out of which 9.6 million died. It is known that people who have Inflammatory Bowel Disease (IBD) turn to be prone to increased risks of...

• Mesenchymal Stem Cells from Human Exfoliated Deciduous Teeth and the Orbicularis Oris Muscle: How Do They Behave When Exposed to a Proinflammatory Stimulus?

  Authors:Alessander Junior Leyendecker, Carla Cristina Gomes Pinheiro, Daniela Yukie Sakai Tanikawa, Jose Ricardo Muniz Ferreira, Mariane Tami Amano, and Daniela Franco BuenoFrom:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 202010,349 words Article 1660LMesenchymal stem cells (MSCs) have been studied as a promising type of stem cell for use in cell therapies because of their ability to regulate the immune response. Although they are classically isolated from the bone...

• Interaction between Stem Cells and the Microenvironment for Musculoskeletal Repair.

  Authors:Yong-Can Huang, Zhen Li, Jun Li, and Feng-Juan LyuFrom:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20201,862 words Article 1560LManipulation of the tissue microenvironment has become a promising method to enhance the regenerative abilities of stem cells/progenitors for musculoskeletal repair. The composition of the microenvironment is determined...

• Hypoxia Promotes Vascular Smooth Muscle Cell (VSMC) Differentiation of Adipose-Derived Stem Cell (ADSC) by Regulating Mettl3 and Paracrine Factors.

  Authors:Jiaying Lin, Qianqian Zhu, Jialyu Huang, Renfei Cai, and Yanping KuangFrom:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20205,343 words Article 1370LAdipose-derived stem cell (ADSC) is an alternative and less invasive source of mesenchymal stem cells which can be used to develop biological treatment strategies for tissue regeneration, and their therapeutic...

• Transplantation of Stem Cells from Human Exfoliated Deciduous Teeth Decreases Cognitive Impairment from Chronic Cerebral Ischemia by Reducing Neuronal Apoptosis in Rats.

  Authors:Shu Zhu, Dongyu Min, Jianhong Zeng, Yetao Ju, Yao Liu, and Xu ChenFrom:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20206,992 words Article 1370LStem cells from human exfoliated deciduous teeth (SHED) are a unique postnatal stem cell population with high self- renewal ability that originates from the cranial neural crest. Since SHED are homologous to the central...

• Functional Comparison between Healthy and Multiple Myeloma Adipose Stromal Cells.

  Authors:Nicolas Espagnolle, Benjamin Hebraud, Jean-Gerard Descamps, Melanie Gadelorge, Marie-Veronique Joubert, Laura Do Souto Ferreira, et al.From:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20204,448 words Report 1410LMultiple myeloma (MM) is an incurable B cell neoplasia characterized by the accumulation of tumor plasma cells within the bone marrow (BM). As a consequence, bone osteolytic lesions develop in 80% of patients and remain...

• Hypermethylation in Calca Promoter Inhibited ASC Osteogenic Differentiation in Rats with Type 2 Diabetic Mellitus.

  Authors:Lei Wang, Feng Ding, Shaojie Shi, Xingxing Wang, Sijia Zhang, and Yingliang SongFrom:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20206,046 words Article 1360LThe abnormal environment of type 2 diabetes mellitus (T2DM) leads to a substantial decrease in osteogenic function of stem cells. However, the gene sequence does not vary before and after disease for the patient. This...

• Curcumin-Activated Mesenchymal Stem Cells Derived from Human Umbilical Cord and Their Effects on MPTP-Mouse Model of Parkinson's Disease: A New Biological Therapy for Parkinson's Disease.

  Authors:Yun-Liang Wang, Xin-Shan Liu, Shan-Shan Wang, Peng Xue, Zhi-Lei Zeng, Xiao-Peng Yang, et al.From:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 202010,213 words Article 1310LBackground. The aim of this study was to investigate the effects of human umbilical cord mesenchymal stem cell activated by curcumin (hUC-MSCs-CUR) on Parkinson's disease (PD). hUC-MSCs can differentiate into many types...

• Generation of Otic Lineages from Integration-Free Human-Induced Pluripotent Stem Cells Reprogrammed by mRNAs.

  Authors:Sarah L. Boddy, Ricardo Romero-Guevara, Ae-Ri Ji, Christian Unger, Laura Corns, Walter Marcotti, et al.From:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20205,522 words Article 1510LDamage to the sensory hair cells and the spiral ganglion neurons of the cochlea leads to deafness. Induced pluripotent stem cells (iPSCs) are a promising tool to regenerate the cells in the inner ear that have been...

• Stromal Cell-Derived Factor-1 Enhances the Therapeutic Effects of Human Endometrial Regenerative Cells in a Mouse Sepsis Model.

  Authors:Wang Jin, Yiming Zhao, Yonghao Hu, Dingding Yu, Xiang Li, Yafei Qin, et al.From:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20207,411 words Article 1430LEndometrial regenerative cells (ERCs) are mesenchymal-like stromal cells obtained from human menstrual blood, whose positive therapeutic effects have been validated in several experimental models. Stromal cell-derived...

• Recent Advance in Source, Property, Differentiation, and Applications of Infrapatellar Fat Pad Adipose-Derived Stem Cells.

  Authors:Yu-chen Zhong, Shi-chun Wang, Yin-he Han, and Yu WenFrom:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20208,404 words Article 1430LInfrapatellar fat pad (IPFP) can be easily obtained during knee surgery, which avoids the damage to patients for obtaining IPFP. Infrapatellar fat pad adipose-derived stem cells (IPFP-ASCs) are also called infrapatellar...

• Organoids as a Powerful Model for Respiratory Diseases.

  Authors:Yu Li, Qi Wu, Xin Sun, Jun Shen, and Huaiyong ChenFrom:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20205,915 words Article 1500LInsults to the alveoli usually lead to inefficient gas exchange or even respiratory failure, which is difficult to model in animal studies. Over the past decade, stem cell-derived self-organizing three-dimensional...

• Interaction between Mesenchymal Stem Cells and Intervertebral Disc Microenvironment: From Cell Therapy to Tissue Engineering.

  Authors:Gianluca Vadala, Luca Ambrosio, Fabrizio Russo, Rocco Papalia, and Vincenzo DenaroFrom:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 202012,490 words Article 1640LLow back pain (LBP) in one of the most disabling symptoms affecting nearly 80% of the population worldwide. Its primary cause seems to be intervertebral disc degeneration (IDD): a chronic and progressive process...

• Tissue Engineering Approaches for Enamel, Dentin, and Pulp Regeneration: An Update.

  Authors:Geraldine M. Ahmed, Eman A. Abouauf, Nermeen AbuBakr, Christof E. Dorfer, and Karim Fawzy El- SayedFrom:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20209,332 words Article 1570LStem/progenitor cells are undifferentiated cells characterized by their exclusive ability for self-renewal and multilineage differentiation potential. In recent years, researchers and investigations explored the prospect...

• Flufenamic Acid Inhibits Adipogenic Differentiation of Mesenchymal Stem Cells by Antagonizing the PI3K/AKT Signaling Pathway.

  Authors:Xuenan Liu, Zheng Li, Hao Liu, Yuan Zhu, Dandan Xia, Siyi Wang, et al.From:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20205,701 words Article 1310LObjectives. Flufenamic acid (FFA) is a representative of the fenamic acids, an important group of NSAIDs. In the present study, we study the effects of FFA on adipogenesis of human mesenchymal stem cells (MSCs) and we...

• Effect of Inflammation on Gingival Mesenchymal Stem/Progenitor Cells' Proliferation and Migration through Microperforated Membranes: An In Vitro Study.

  Authors:M. Al Bahrawy, K. Ghaffar, A. Gamal, K. El- Sayed, and V. IaconoFrom:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20204,247 words Article 1450LBackground. In the field of periodontal guided tissue regeneration, microperforated membranes have recently proved to be very promising periodontal regenerative tissue engineering tools. Regenerative periodontal...

• Modeling Parkinson's Disease Using Induced Pluripotent Stem Cells.

  Authors:Xinchao Hu, Chengyuan Mao, Liyuan Fan, Haiyang Luo, Zhengwei Hu, Shuo Zhang, et al.From:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 202011,146 words Article 1390LParkinson's disease (PD) is the second most common neurodegenerative disease. The molecular mechanisms of PD at the cellular level involve oxidative stress, mitochondrial dysfunction, autophagy, axonal transport, and...

• Copper Does Not Induce Tenogenic Differentiation but Promotes Migration and Increases Lysyl Oxidase Activity in Adipose-Derived Mesenchymal Stromal Cells.

  Authors:Marta Milewska, Anna Burdzinska, Katarzyna Zielniok, Katarzyna Siennicka, Slawomir Struzik, Piotr Zielenkiewicz, et al.From:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20207,852 words Article 1440LBackground. Copper belongs to the essential trace metals that play a key role in the course of cellular processes maintaining the whole body's homeostasis. As there is a growing interest in transplanting mesenchymal...

• Antioxidant Properties of Tonsil-Derived Mesenchymal Stem Cells on Human Vocal Fold Fibroblast Exposed to Oxidative Stress.

  Authors:Sung-Chan Shin, Hyung-Sik Kim, Yoojin Seo, Cho Hee Kim, Ji Min Kim, Hyun-Keun Kwon, et al.From:Stem Cells InternationalPeer-Reviewed

  Mar. 31, 20205,948 words Article 1460LThe therapeutic potential of tonsil-derived mesenchymal stem cells (TMSCs) has been proved in several in vitro and in vivo models based on their antioxidative capacity. Oxidative stress is involved in the formation of...