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From:Stem Cells International (Vol. 2020) Peer-ReviewedPeriodontal disease (PD) is one of the main causes of tooth loss and is related to oxidative stress and chronic inflammation. Although different treatments have been proposed in the past, the vast majority do not...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedCerebral palsy (CP) is a kind of movement and posture disorder syndrome in early childhood. In recent years, human mesenchymal stem cell (hMSC) transplantation has become a promising therapeutic strategy for CP. However,...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedRenal disease is a major issue for global public health. Despite some progress in supportive care, the mortality rates among patients with this condition remain alarmingly high. Studies in pursuit of innovative...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedIn the article titled "RSP5 Positively Regulates the Osteogenic Differentiation of Mesenchymal Stem Cells by Activating the K63-Linked Ubiquitination of Akt" [1], the affiliation should be changed from "Department of...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedIntroduction. Microfragmented adipose tissue (MFAT) has been shown to benefit osteoarthritic patients by reducing pain and supporting tissue regeneration through a mesenchymal stem cell (MSC)-related paracrine mechanism....
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From:Stem Cells International (Vol. 2020) Peer-ReviewedEsophageal squamous cell carcinoma (ESCC) is a frequent malignant tumor with low 5-year overall survival. Targeting ESCC tumor-initiating cells (TICs) may provide a new research avenue to achieve better therapeutic...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedIt has been suggested that mechanical strain may elicit cell differentiation in adult somatic cells through activation of epithelial sodium channels (ENaC). However, such phenomenon has not been previously demonstrated...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedMarrow stromal cells (MSCs) are in different stages of clinical trials for stroke patients. MSCs are proposed to promote recovery through the release of secretomes that modulate the function of beneficial immune cells....
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From:Stem Cells International (Vol. 2020) Peer-ReviewedAdipogenesis is the process through which preadipocytes differentiate into adipocytes. During this process, the preadipocytes cease to proliferate, begin to accumulate lipid droplets, and develop morphologic and...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedMesenchymal stem cells (MSCs), discovered and isolated from the bone marrow in the 1960s and with self-renewal capacity and multilineage differentiation potential, have valuable immunomodulatory abilities. Acute kidney...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedBackground. Ischemia reperfusion injury (IRI) is the major cause of intestinal damage in clinic. Although either mesenchymal stromal cells (MSCs) or interleukin 37 (IL-37) shows some beneficial roles to ameliorate IRI,...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedThe precise mechanism about drug resistance of cancer stem cells (CSCs) has not yet been completely understood. Based on the expression of CD44 and CD133, two well-recognized cell surface markers for CSC identification,...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedPurpose. Recent evidence has shown that [CD4.sup.+] T helper (Th) cells are involved in renal inflammation and fibrosis. However, whether renal fibrosis can be alleviated by intervening in the polarization of [CD4.sup.+]...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedIntroduction. A recent attractive option regarding mesenchymal stem cells (MSC) application is the treatment of bone cystic lesions and in particular aneurysmal bone cysts (ABC), in order to stimulate intrinsic healing....
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From:Stem Cells International (Vol. 2020) Peer-ReviewedIn the past few years, intensive research has focused on corneal stem cells as an unlimited source for cell-based therapy in regenerative ophthalmology. Today, it is known that the cornea has at least two types of stem...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedThe mesenchymal stem cells (MSCs) are known as highly plastic stem cells and can differentiate into specialized tissues such as adipose tissue, osseous tissue, muscle tissue, and nervous tissue. The differentiation of...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedBackground. Human bone marrow stromal/stem cells (hMSCs, also known as the skeletal stem cells or mesenchymal stem cells) are being employed to study lineage fate determination to osteoblasts, adipocytes, and...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedObjective. Ascorbic acid (AA) and controlled inflammatory stimuli are postulated to possess the ability to independently exert positive effects on a variety of proliferative, pluripotency, and differentiation attributes...
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From:Stem Cells International (Vol. 2020) Peer-ReviewedIn the article titled "Preconditioning of Rat Bone Marrow-Derived Mesenchymal Stromal Cells with Toll-Like Receptor Agonists" [1], there was an error in the production of Figure 2(b) which resulted in some colouration...