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From:eLife (Vol. 11) Peer-ReviewedActing in the world is accompanied by a sense of agency, or experience of control over our actions and their outcomes. As humans, we can report on this experience through judgments of agency. These judgments often occur...
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From:eLife (Vol. 11) Peer-ReviewedThe spike protein of SARS-CoV-2 triggers macrophages and epithelial cells to produce excess levels of pro-inflammatory molecules, which can do more harm than good. Byline: Tomohiro Sawa, Takaaki Akaike...
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From:eLife (Vol. 11) Peer-ReviewedIntegrin adhesion complexes (IACs) are integrin-based plasma-membrane-associated compartments where cells sense environmental cues. The physical mechanisms and molecular interactions that mediate initial IAC formation...
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From:eLife (Vol. 11) Peer-ReviewedTriggered activity bursts in place cells can increase and decrease the strength of some inputs. Byline: Xingyun Wang, Richard Naud ************************************************************************ Related...
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From:eLife (Vol. 11) Peer-ReviewedT cell activation requires engagement of a cognate antigen by the T cell receptor (TCR) and the co-stimulatory signal of CD28. Both TCR and CD28 aggregate into clusters at the plasma membrane of activated T cells. While...
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From:eLife (Vol. 11) Peer-ReviewedGene regulatory networks coordinate the formation of organs and structures that compose the evolving body plans of different organisms. We are using a simple chordate model, the Ciona embryo, to investigate the essential...