Prone positioning improves oxygenation and lung recruitment in patients with SARS-CoV-2 acute respiratory distress syndrome; a single centre cohort study of 20 consecutive patients.

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From: BMC Research Notes(Vol. 14, Issue 1)
Publisher: BioMed Central Ltd.
Document Type: Report
Length: 2,832 words
Lexile Measure: 1520L

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Abstract :

Objective We aimed to characterize the effects of prone positioning on respiratory mechanics and oxygenation in invasively ventilated patients with SARS-CoV-2 ARDS. Results This was a prospective cohort study in the Intensive Care Unit (ICU) of a tertiary referral centre. We included 20 consecutive, invasively ventilated patients with laboratory confirmed SARS-CoV-2 related ARDS who underwent prone positioning in ICU as part of their management. The main outcome was the effect of prone positioning on gas exchange and respiratory mechanics. There was a median improvement in the PaO.sub.2/FiO.sub.2 ratio of 132 in the prone position compared to the supine position (IQR 67-228). We observed lower PaO.sub.2/FiO.sub.2 ratios in those with low ( median) static compliance (P Keywords: Respiratory distress syndrome, Adult, Prone position, Severe acute respiratory syndrome coronavirus 2

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Gale Document Number: GALE|A650601639