Usefulness of Leucocyte Cell Population Data by Sysmex XN1000 Hematology Analyzer in Rapid Identification of Acute Leukemia.

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Publisher: Springer
Document Type: Report; Brief article
Length: 271 words

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Keywords: Automated hematology analyzers; Acute leukemia; CPD; Sysmex XN 1000 Abstract Leukocyte cell population data (CPD) generated by hematology auto analyzers are reported to be useful in screening of sepsis patients. However, there is a paucity of literature highlighting the utility of CPD in screening of acute leukemias (AL). Leucocyte CPD obtained by Sysmex XN1000 hematology analyzer from 210 cases of ALs [22 acute promyelocytic leukemia (APL), 79 non-APL acute myeloid leukemia (non-APL-AML) and 109 acute lymphoblastic leukemia (ALL)] were compared with 100 healthy and 52 reactive controls. Receiver operator curves were drawn to determine the cut-off values of individual parameters. The regression equations combining the best parameters were then formulated to calculate a cut-off value for discrimination among AL subgroups and controls. Acute leukemias showed significant differences (p Author Affiliation: (1) Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Bhubaneswar, India (2) Department of Medical Oncology/Hematology, All India Institute of Medical Sciences, Bhubaneswar, India (b) Article History: Registration Date: 09/08/2021 Received Date: 04/30/2021 Accepted Date: 09/07/2021 Online Date: 09/28/2021 Byline:

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Gale Document Number: GALE|A707789945