New Multiple Myeloma Study Findings Have Been Reported by Researchers at Millennium Pharmaceuticals

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Date: Jan. 7, 2012
Publisher: NewsRX LLC
Document Type: Article
Length: 419 words
Lexile Measure: 1370L

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"Background In multiple myeloma, expression of cancer testis antigens may provide prognostic markers and potential targets for immunotherapy. Expression at relapse has not yet been evaluated for a large panel of cancer testis antigens which can be classified by varying expression in normal tissue: restricted to testis, expressed in testis and brain and not restricted but selectively expressed in testis," scientists in Cambridge, Massachusetts report (see also Multiple Myeloma).

"Design and Methods Evaluation of cancer testis antigen expression was made in newly diagnosed multiple myeloma cases (HOVON-65/GMMG-HD4 trial; n=320) and in relapse cases (APEX, SUMMIT, CREST trials; n=264). Presence of expression using Affymetrix GeneChips...

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Gale Document Number: GALE|A276471709