A case of decreased susceptibility to ceftriaxone in Neisseria gonorrhoeae in the absence of a mosaic penicillin-binding protein 2 (penA) allele

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From: Sexually Transmitted Diseases(Vol. 44, Issue 8)
Publisher: American Venereal Disease Association
Document Type: Author abstract
Length: 52 words

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Abstract :

We report a case of Neisseria gonorrhoeae with a non-mosaic penA allele that exhibited decreased susceptibility to extended-spectrum cephalosporins, including a ceftriaxone minimum inhibitory concentration of 0.5 [micro]g/mL. An analysis of resistance determinants suggested that the observed phenotypc might have resulted from the combined effects of mutations in multiple genes. DOI: 10.1097/OLQ.0000000000000645

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Gale Document Number: GALE|A500499949