Temperature-Dependent Residue Depletion Regularities of Tiamulin in Nile Tilapia (Oreochromis niloticus) Following Multiple Oral Administrations.

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Date: June 11, 2021
Publisher: Frontiers Research Foundation
Document Type: Article
Length: 440 words
Lexile Measure: 1440L

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Author(s): Cuiyv Cao, Yongtao Liu, Guodong Zhang, Jing Dong, Ning Xu, Shun Zhou, Yibin Yang, Qiuhong Yang, Xiaohui Ai

The aim of this study was to investigate the effect of different water temperatures (19, 25, and 30°C) on tissue residue depletion of tiamulin in Nile tilapia (<italic>Oreochromis niloticus</italic>) after five consecutive days of oral administration at the dose of 20 mg/kg body weight and to calculate the corresponding elimination half-life (<italic>T</italic><sub>1/2</sub>) and withdrawal times (WTs). After oral administration at scheduled 11 time points (1, 2, 3, 5, 7, 9, 12, 15, 20, 25, and 30 days), samples of plasma and tissues (muscle plus skin, liver, kidney, and gill) were collected....

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Gale Document Number: GALE|A664884169