Predictive value of the test of infant motor performance and the Hammersmith infant neurological examination for cerebral palsy in infants.

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From: Early Human Development(Vol. 174)
Publisher: Elsevier B.V.
Document Type: Report
Length: 425 words

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Keywords Cerebral palsy; Test of infant motor performance; Hammersmith infant neurological examination; Neurodevelopment; Infant Highlights * The HINE and the TIMP are low-resource tools useful in the assessment of infant development * HINE total score is predictive of CP diagnosis for high-risk infants 3-4 months CA * Concurrent administration of the TIMP and the HINE did not add predictive value for CP Abstract Background Current recommendations for early detection tools for cerebral palsy (CP) include assessments that vary in feasibility and resource requirements. The predictive value of less resource-intensive tools has not been fully explored. Aims To determine the predictive value of the Test of Infant Motor Performance (TIMP) at 3--4 months corrected age (CA) for CP, and whether administration of both the TIMP and the Hammersmith Infant Neurological Exam (HINE) improves early CP detection. Study design Five-year retrospective observational study of infants who received the TIMP and the HINE at 3--4 months CA in a high-risk follow-up clinic. TIMP and HINE cut-off scores (alone and in combination) were compared for CP discriminatory ability. Subjects Of patients with HINE scores (n = 1389; 676 [48.7 %] female; median gestational age at birth 31 weeks [interquartile range 29--34 weeks]), 1343 had concurrent TIMP scores available. Outcome measures Clinical diagnosis of CP. Results HINE total score Conclusions HINE total score Author Affiliation: (a) Center for Perinatal Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, 700 Children's Drive, Research Building III, Columbus, OH 43205, USA (b) Biostatistics Core, Abigail Wexner Research Institute at Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA (c) The Ohio State University College of Medicine, 370 W 9th Ave, Columbus, OH 43210, USA (d) Emory University School of Medicine, 1440 Clifton Rd, Atlanta, GA 30322, USA (e) Children's Healthcare of Atlanta, 1405 Clifton Rd NE, Atlanta, GA 30322, USA * Corresponding author at: Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA. Article History: Received 25 March 2022; Revised 2 September 2022; Accepted 4 September 2022 Byline: Lindsay Pietruszewski [] (a,*), Melissa Moore-Clingenpeel (b), Gregory C.J. Moellering (c), Dennis Lewandowski (a), Nancy Batterson (a), Nathalie L. Maitre (d,e)

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Gale Document Number: GALE|A723925859