Characterization of Sulfated Anti-HIV Antibody using an Expanded Genetic code

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Date: May 22, 2018
From: Biochemistry(Vol. 57, Issue 20)
Publisher: American Chemical Society
Document Type: Report
Length: 50 words

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Abstract :

The Study uses an upgraded expanded genetic code for sulfotyrosine (sY) to express homogeneous E51 sulfoforms containing up to five sulfates and the results reveal that gp120 binding by E51 requires very specific sulfation patterns and should aid in the further design of sulfated E51-based peptides and immunoadhesins against HIV.

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Gale Document Number: GALE|A542238660