Role of AMP-activated protein kinase in ferritin H gene expression by resveratrol in human T cells

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Authors: Kenta Iwasaki, Takaaki Kobayashi, Kensuke Sakamoto, Bo-Wen Huang, Yoshiaki Tsuji and Paul D. Ray
Date: July 30, 2013
From: Biochemistry(Vol. 52, Issue 30)
Publisher: American Chemical Society
Document Type: Report
Length: 53 words

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Abstract :

The antioxidant responsive element (ARE)-dependent transcriptional activation of the ferritin heavy chain (ferritin H) gene by resveratrol in human T cells was investigated. The AMP-activated protein kinase (AMPK) was found to play an important role in the activation of nuclear factor E2-related factor (Nrf2) and subsequent ARE-dependent ferritin H gene transcription by resveratrol.

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Source Citation   

Gale Document Number: GALE|A355203419