Exosomes as Crucial Players in Pathogenesis of Systemic Lupus Erythematosus.

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Date: July 20, 2022
Publisher: Hindawi Limited
Document Type: Article
Length: 9,056 words
Lexile Measure: 1370L

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Abstract :

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that affects multiple systems. Its clinical manifestation varies across patients, from skin mucosa to multiorgan damage to severe central nervous system involvement. The exosome has been shown to play an important role in the pathogenesis of autoimmune diseases, including SLE. We review the recent knowledge of exosomes, including their biology, functions, mechanism, and standardized extraction and purification methods in SLE, to highlight potential therapeutic targets for SLE.

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Source Citation   

Gale Document Number: GALE|A712138547