Abstract :
Keywords Bayley scales; Early childhood development; Stability; Predictive ability; Intellectual abilities Highlights * Longitudinal studies examining psychometric properties of the Bayley scales in low-to-middle income countries are lacking. * In a large cohort of Nepalese children, stability of the Bayley scales was poor in infancy but improved with age. * The relationship between the Bayley scales and to future intellectual abilities improved with age in early childhood. * The low stability of the Bayley scales must be considered in research projects measuring early child development. * For prediction of future intellectual abilities, measurements taken after the children are 2-3 years are preferrable. Abstract Background The Bayley Scales of Infant and Toddler Development is widely used worldwide. The objective of the current study was to measure the stability of the Bayley Scales during early childhood and its relationship with intellectual abilities at four years in young Nepalese children. Methods In a prospective cohort we used the Bayley 3rd edition to measure early child development in 529 Nepalese children at 6--11, 18--23 and 30--35 months. At four years, we used the Wechsler Preschool and Primary Scale of Intelligence (WPPSI) to measure intellectual abilities. We expressed the stability of the Bayley scores by intraclass correlation coefficients (ICCs) and concordance correlation coefficients (CCCs). The relationship between the Bayley scores and the WPPSI full-scale IQ (FSIQ) at four years was examined in regression models. Results The ICCs between the Bayley scores across timepoints were 0.01 (95 % CI -0.06, 0.04), 0.19 (95 % CI 0.15, 0.26) and 0.22 (95 % CI 0.17, 0.28) for the Cognitive, Language and Motor composite scores. The CCC for the composite scores ranged from 0.05 to 0.20 between 6 and 11 and 30--35 months and from 0.20 to 0.36 between 18 and 23 and 30--35 months. The Bayley scores at 6--11, 18--23 and 30--35 months explained 3 %, 20 % and 36 % of the variation of the FSIQ. Conclusion The stability of the Bayley scales is poor in early childhood, and its relationship with future intellectual abilities is poor in infancy but improves slightly with age in early childhood. Findings from this large community-based cohort of healthy at-risk children are relevant when measuring early child development worldwide. Author Affiliation: (a) Regional Centre for Child and Youth Mental Health and Child Welfare, NORCE Norwegian Research Centre, Bergen, Norway (b) Department of Research, Innlandet Hospital Trust, Lillehammer, Norway (c) Department of Psychosocial Science, Faculty of Psychology, University of Bergen, Bergen, Norway (d) Department of Child Health, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal (e) Centre for Intervention Science in Maternal and Child Health, Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (f) Department of Community Medicine, Kathmandu Medical College, Kathmandu, Nepal * Corresponding author at: Regional Centre for Child and Youth Mental Health and Child Welfare, NORCE Norwegian Research Centre, Nygårdsgaten 112, 5008 Bergen, Norway. Article History: Received 19 August 2021; Revised 11 December 2021; Accepted 11 June 2022 Byline: Ingrid Kvestad [inkv@norceresearch.no] (a,b,*), Mari Hysing (c), Suman Ranjitkar (d), Merina Shrestha (d), Manjeswori Ulak (d,e), Ram K. Chandyo (f), Tor A. Strand (b)