Mini-aortic valve replacements are not associated with an increased incidence of patient--prosthesis mismatch: a propensity-scored analysis

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Publisher: Springer
Document Type: Report
Length: 376 words

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To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: Byline: J. Trent Magruder (1), Joshua C. Grimm (1), Arman Kilic (1), Todd Crawford (1), John V. Conte (1), Duke E. Cameron (1), Ashish S. Shah (2) Keywords: Aortic valve; Aortic valve replacement; Patient--prosthesis mismatch; Median sternotomy; Hemisternotomy Abstract: Objectives We sought to determine whether an AVR performed though a partial upper hemisternotomy ("mini-AVR") resulted in a greater incidence of patient--prosthesis mismatch (PPM) than those through a full median sternotomy ("AVR"). Methods Patients undergoing isolated aortic valve replacement from 2008 to 2013 were identified. Moderate PPM was defined as an in vivo effective orifice area a[currency]0.85 cm.sup.2/m.sup.2 body surface area severe PPM was defined as a[currency]0.65 cm.sup.2/m.sup.2. A propensity score-matched analysis was utilized to compare the incidence of PPM between these groups. Results Of the 630 patients undergoing aortic valve surgery, 90 (14.3 %) received mini-AVRs and 540 (85.7 %) received regular AVRs. After propensity matching, we established two cohorts of 85 patients receiving each procedure. Both cohorts were similar with regard to all preoperative covariates including mean age (65.5 vs. 65.1, p = 0.85), diabetes (17.7 vs. 22.4 %), mean BMI (28.3 vs. 28.6, p = 0.73), mean EF (56.9 vs. 55.6, p = 0.43), proportion of patients with aortic stenosis (70.6 vs. 71.8 %, p = 1.00), preoperative valve area (0.88 vs. 0.93 cm.sup.2, p = 0.67), and proportion who received a bioprosthesis (85.9 vs. 83.5 %, p = 0.59). Postoperatively, 27.4 % of mini-AVRs and 26.8 % of AVRs had moderate PPM (p = 0.93) 2.4 and 1.2 % had severe PPM (p = 0.66). Kaplan--Meier analysis also failed to reveal a difference in 1-year survival between mini and regular AVRs (93.7 vs. 90.5 %, p = 0.49). Conclusions After propensity matching, mini-AVRs are not associated with a greater incidence of PPM than regular AVRs. Severe PPM was rare across both procedure types in this surgical series. Author Affiliation: (1) Division of Cardiac Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA (2) Department of Cardiac Surgery, Vanderbilt University School of Medicine, 1215 21st Avenue South, Suite 5025, Nashville, TN, 37232, USA Article History: Registration Date: 07/12/2015 Received Date: 02/09/2015 Accepted Date: 04/12/2015 Online Date: 19/12/2015

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Gale Document Number: GALE|A444717187