A Retrospective Study of the Impact of Intraoperative Intact Parathyroid Hormone Monitoring During Total Parathyroidectomy for Secondary Hyperparathyroidism: STARD Study.

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From: Medicine(Vol. 94, Issue 29)
Publisher: Lippincott Williams & Wilkins, WK Health
Document Type: Report; Author abstract; Brief article
Length: 197 words

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Byline: Takahisa Hiramitsu, From the Department of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital (TH, YT, MO, TY); and Department of Transplant Immunology, Nagoya University School of Medicine, Showa-ku, Nagoya, Aichi, Japan (TK).; Yoshihiro Tominaga; Manabu Okada; Takayuki Yamamoto; Takaaki Kobayashi Abstract The study aimed to evaluate the diagnostic accuracy of intraoperative intact parathyroid hormone (IO-iPTH) in patients with secondary hyperparathyroidism (HPT).The cut-off for IO-iPTH monitoring remains unknown.This was a single-center retrospective review of 226 consecutive patients (107 males and 119 females) who underwent parathyroidectomy for secondary HPT between May 2010 and March 2014. The predetermined cut-off for IO-iPTH was a 70% IO-iPTH drop from baseline 10Çèminutes after total parathyroidectomy and thymectomy. We used 60Çèpg/mL iPTH value (POD1) was significantly higher than that in patients with 70% IO-iPTH drop were 97.5%, 52.2%, and 92.9%, respectively, this criterion was demonstrated to be beneficial in 26 patients. In 5 patients, 70% IO-iPTH drop enabled termination of operations and iPTH value (POD1) was

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Gale Document Number: GALE|A671691399