Effects of family-oriented dignity therapy on dignity, depression and spiritual well-being of patients with lung cancer undergoing chemotherapy: A randomised controlled trial.

Citation metadata

Publisher: Elsevier B.V.
Document Type: Report
Length: 469 words

Document controls

Main content

Abstract :

Keywords Dignity; Depression; Spiritual well-being; Family; Cancer; Chemotherapy Abstract Background Enhancing patients' sense of dignity is the core element of high-quality palliative care. In Western countries, dignity therapy has shown promising positive effects on the sense of dignity and end-of-life experience. To apply this therapy in Chinese patients, a theory-driven, culturally relevant family-oriented dignity therapy was developed, guided by the Medical Research Council framework for complex intervention development. Objectives This study examined the effectiveness of family-oriented dignity therapy in improving dignity-related distress, depression, and spiritual well-being in Chinese patients with lung cancer undergoing chemotherapy. Design A randomised controlled trial. Settings and methods Patients who were diagnosed with lung cancer and undergoing chemotherapy were recruited using convenience sampling from a cancer hospital in Changsha, China. A significant family caregiver of each patient was invited to participate. Patients who met the inclusion criteria and agreed to participate (N = 120) were randomly assigned to receive family-oriented dignity therapy (intervention group, n = 60) or attention (control group, n = 60). The Patient Dignity Inventory, Patient Health Questionnaire-9, and Functional Assessment of Chronic Illness Therapy -- Spiritual Well-being Scale were used to assess dignity-related distress, depression, and spiritual well-being, respectively, at baseline and 1- and 4-week follow-up. A generalised estimating equation was used to analyse the intervention effects across the time points. Results Compared with the control group, the patients in the intervention group showed significantly greater reduction in existential distress ([beta]: -1.372, 95% CI: -2.269, -0.472; p = 0.003) and depression ([beta]: -3.430, 95% CI: -5.032, -1.829; p Conclusions Family-oriented dignity therapy has the potential to relieve existential distress and depressive symptoms and improve spiritual well-being. We expect our finding to impact research on family-oriented dignity therapy and enhance its effectiveness. We may also have an impact on nursing practice by providing a means to initiate conversations between nurses and the patients and family caregivers to relieve the psychosocial distress of patients during treatment. This study has been registered in the Chinese Clinical Trial Registry (registration number: ChiCTR1900020806). Author Affiliation: (a) Xiangya School of Nursing, Central South University, No: 172 Tongzipo Road, Yuelu District, Changsha, China (b) The Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Room 732, Esther Lee Building, Shatin, N. T., Hong Kong, China * Corresponding author. Article History: Received 16 July 2021; Revised 22 February 2022; Accepted 24 February 2022 Byline: Jinnan Xiao [jnxiao2021@csu.edu.cn] (a), Ka Ming Chow [kmchow@cuhk.edu.hk] (b), Kai Chow Choi [kchoi@cuhk.edu.hk] (b), S.N. Marques Ng [marquesng@cuhk.edu.hk] (b), Chongmei Huang [huangcm@csu.edu.cn] (a), Jinfeng Ding [jinfeng.ding@csu.edu.cn] (a), W.H. Carmen Chan [whchan@cuhk.edu.hk] (b,*)

Source Citation

Source Citation   

Gale Document Number: GALE|A700885977