Role of the Cysteine 81 Residue of Macrophage Migration Inhibitory Factor as a Molecular Redox Switch

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From: Biochemistry(Vol. 57, Issue 9)
Publisher: American Chemical Society
Document Type: Report
Length: 47 words

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Abstract :

The article discusses roles of cysteine 81 within macrophage migration inhibitory factor (MIF) serves as eswitch cysteineE for conversion of structural isoform redMIF to oxMIF. Topics include significant structural rearrangements of protein resulting in decreased ?-sheet content and increased random coil content by maintaining trimeric quaternary structure.

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Source Citation   

Gale Document Number: GALE|A534791161