Changes in Retinal Structure and Ultrastructure in the Aged Mice Correlate With Differences in the Expression of Selected Retinal miRNAs.

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Publisher: Frontiers Research Foundation
Document Type: Article
Length: 407 words
Lexile Measure: 1430L

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Author(s): Anca Hermenean, Maria Consiglia Trotta, Sami Gharbia, Andrei Gelu Hermenean, Victor Eduard Peteu, Cornel Balta, Coralia Cotoraci, Carlo Gesualdo, Settimio Rossi, Mihaela Gherghiceanu, Michele D'Amico

Age and gender are two important factors that may influence the function and structure of the retina and its susceptibility to retinal diseases. The aim of this study was to delineate the influence that biological sex and age exert on the retinal structural and ultrastructural changes in mice and to identify the age-related miRNA dysregulation profiles in the retina by gender. Experiments were undertaken on male and female Balb/c aged 24months (approximately 75-85years in humans)...

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Gale Document Number: GALE|A648225261