Early versus delayed oral feeding after gastrectomy for gastric cancer: A systematic review and meta-analysis.

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Publisher: Elsevier B.V.
Document Type: Report
Length: 510 words

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Keywords Delayed oral feeding; Early oral feeding; Gastrectomy; Gastric cancer; Meta-analysis; Systematic review Abstract Background Early oral feeding has been shown to be safe and effective for most surgeries, while surgeons and nurses are still hesitant to implement it in gastric cancer patients who undergo gastrectomy. Objectives This review aimed to investigate the safety and feasibility of early versus delayed oral feeding in gastric cancer patients after gastrectomy. Design A systematic review and meta-analysis of randomized controlled trials. Data sources The literature search was performed in 7 databases from inception to March 7, 2021. Review methods Randomized controlled trials that compared the effects of early oral feeding and delayed oral feeding in gastric cancer patients who undergo gastrectomy were included. The primary outcome was hospital days, and secondary outcomes included hospital costs, postoperative complication rates, feeding intolerance rates, annal exhaust time, albumin levels and prealbumin levels. According to the presence of heterogeneity, fixed or random effect meta-analysis was applied. Results Nine trials involving 1087 gastric cancer patients who undergo gastrectomy were pooled in this systemic review and meta-analysis. The results showed that early oral feeding significantly decreased hospital days (mean difference = -1.50, 95% confidence interval = -1.91 to -1.10, P Conclusions For gastric cancer patients who undergo gastrectomy, early oral feeding was associated with shorter hospital days and lower hospital costs, but early oral feeding did not increase the incidences of postoperative complications or feeding intolerance. Moreover, early oral feeding also decreased the annal exhaust time but increased the levels of albumin and prealbumin. Author Affiliation: (a) Department of Nursing, Daping Hospital, Army Medical University, Chongqing, China (b) Department of Basic Nursing, School of Nursing, Army Medical University, Chongqing, China (c) Department of Digestion, The 958st Hospital, Chongqing, China (d) Department of Gastrointestinal Colorectal and Anal Surgery, Daping Hospital, Army Medical University, Chongqing, China * Corresponding authors. Article History: Received 28 March 2021; Revised 13 October 2021; Accepted 19 October 2021 (footnote)1 These authors contributed equally to this work. Byline: Haiyan He (a,1), Yuanyuan Ma (b,1), Zhiwei Zheng (c), Xiaolian Deng (d), Jingci Zhu [zhujingci2009@163.com] (b,*), Yaling Wang [930706229@qq.com] (a,*)

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Gale Document Number: GALE|A689867772