The Sydney classification criteria for definite antiphospholipid syndrome: clinical, laboratory, and experimental insights have been addressed

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Authors: Neha Garg and Atul Deodhar
Date: Apr. 2012
From: The Journal of Musculoskeletal Medicine(Vol. 29, Issue 3)
Publisher: CMP Medica, LLC
Document Type: Report
Length: 2,611 words
Lexile Measure: 1540L

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Abstract :

Amendments to the Sapporo criteria for antiphospholipid syndrome (APS) addressed clinical, laboratory, and experimental insights gained since they were adopted in 1999. A committee of experts concurred that patients with APS should be stratified according to the presence or absence of other (inherited or acquired) contributing causes of thrombosis. It was agreed that there are inherent problems in applying the pregnancy-related morbidity criterion in practice and research because there is no widely accepted definition for placental insufficiency or characteristic histopathological placental abnormality in APS. Both lupus anticoagulant and anticardiolipin antibodies were maintained as laboratory criteria. The issue of several other APS-related conditions (cardiac, neurological, skin, or renal; thrombocytopenia) also was addressed. The newer criteria have several advantages over the older ones but also have limitations. (JMusculoskel Med. 2012;29:73-77)

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Gale Document Number: GALE|A306357957