Q/Does platelet-rich plasma improve patellar tendinopathy symptoms?

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From: Journal of Family Practice(Vol. 71, Issue 4)
Publisher: Jobson Medical Information LLC
Document Type: Report
Length: 786 words
Lexile Measure: 1290L

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EVIDENCE-BASED ANSWER

A / IT'S UNCLEAR. High-quality data have not consistently established the effectiveness of platelet-rich plasma (PRP) injections to improve symptomatic recovery in patellar tendinopathy, compared to placebo (strength of recommendation [SOR]: A, based on 3 small randomized controlled trials [RCTs]). The 3 small RCTs included only 111 patients, total. One found no evidence of significant improvement with PRP compared to controls. The other 2 studies showed mixed results, with different outcome measures favoring different treatment groups and heterogeneous results depending on follow-up duration.

Evidence summary

Symptoms improve with PRP--but not significantly

A 2014 double-blind RCT (n = 23) explored recovery outcomes in patients with patellar tendinopathy who received either 1 injection of leukocyte-rich PRP or ultrasound-guided dry needling. (1) Both groups also completed standardized eccentric exercises. Participants were predominantly men, ages >18 years. Symptomatic improvement was assessed using the Victorian Institute of Sport Assessment-Patella (VISA-P), an 8-item subjective questionnaire of functionality with a range of 0 to 100, with 100 as the maximum score for an asymptomatic individual.

At 12 weeks posttreatment, VISA-P scores improved in both groups. However, the improvement in the dry needling group was not statistically significant (5.2 points; 95% CI,...

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Gale Document Number: GALE|A712558628